真菌病是一种双态真菌病,通常在免疫受损的个体中传播并致命。在案例报告中,我们介绍了一个间歇性发热的病人,盗汗,咳嗽和痰。胸部计算机断层扫描显示双肺有多个软组织结节。常规病理和微生物学测试未确认诊断。因此,我们在支气管肺泡灌洗液中使用宏基因组下一代测序进行了病原体检测,并确定了由东方白纹引起的肺部感染(Es.东方)。在抗真菌治疗期间,患者出现肾功能损害,我们尝试了各种抗真菌药物来治疗。最后,病人的病情得到了控制。因此,宏基因组下一代测序病原体检测至关重要.
我们报告了一例由东方白纹真菌引起的罕见疾病(Es。东方)。病人发烧了,在他的肺部发现咳嗽和小肿块。我们使用一种称为宏基因组下一代测序的方法来诊断这种疾病,该方法从患者样本中的DNA中鉴定出真菌。给病人的药物起作用了,但这确实导致了他肾脏的一些问题.该报告可以帮助告知患者未来的治疗方式。
Emergomycosis is a dimorphic fungal disease that is typically disseminated and fatal among immunocompromised individuals. In the case report, we presented a patient with intermittent fever, night sweats, coughing and phlegm. Chest computed tomography revealed multiple soft-tissue nodules in both lungs. Routine pathological and microbiological tests did not confirm the diagnosis. Therefore, we conducted pathogen detection using metagenomic next-generation sequencing in bronchoalveolar lavage fluid and identified the pulmonary infection caused by Emergomyces orientalis (Es. orientalis). During the antifungal treatment, the patient experienced renal function damage, and we have attempted various antifungal drugs for treatment. Finally, the patient\'s condition was brought under control. Therefore, the metagenomic next-generation sequencing pathogen detection was essential.
We report a case of a rare illness caused by the fungus Emergomyces orientalis (Es. orientalis). The patient had a fever, cough and small lumps were found in his lungs. We diagnosed the illness using a method called metagenomic next-generation sequencing that identified the fungus from the DNA in a patient sample. The drug that was given to the patient worked, but it did cause some issues with his kidneys. This report can help to inform how patients are treated in the future.