■随着年轻人中与电子烟相关或与电子烟相关的肺损伤(EVALI)的迅速增加,使用电子烟(或电子烟)的肺部影响在2019年成为医疗保健问题。这导致了成千上万的青少年和年轻人的重症监护。肺功能成像定位良好,可以提供有关vaping的急性和慢性影响的信息。我们进行了系统评价,以检索相关的影像学研究,这些研究描述了与蒸发相关的肺结构功能异常的急性和慢性影像学发现。
■6月13日进行了系统审查,2023年使用PubMed使用以下标准搜索已发布的手稿:[(\“Vaping\”或\“电子烟\”或\“EVALI\”)和(\“MRI\”或\“CT\”或\“成像\”)]。我们只纳入了涉及人类参与者的研究,电子烟/电子烟的使用,MRI,CT和/或PET。
■搜索确定了445份手稿,其中110名(668名独特参与者)特别提到MRI,PET或CT成像的病例或回顾性病例系列的患者。这包括105篇CT特有的手稿(626名参与者),三份主要使用核磁共振成像的手稿(23名参与者),和两份描述PET研究结果的手稿(20名参与者)。大多数研究在北美进行(n=90),其余研究在欧洲进行(n=15),亚洲(n=4)和南美洲(n=1)。绝大多数出版物描述了案例研究(n=93),少数描述了较大的回顾性或前瞻性研究(n=17)。在电子烟使用者和EVALI患者中,主要的CT发现包括毛玻璃混浊,合并和胸膜下保留,MRI显示通气异常,灌注和通气/灌注匹配,而PET显示肺部炎症的证据。
肺结构和功能成像异常常见于EVALI患者和有或没有呼吸道症状的电子烟使用者,这表明功能性MRI可能有助于研究与使用电子烟相关的肺部健康影响。
UNASSIGNED: The pulmonary effects of e-cigarette use (or vaping) became a healthcare concern in 2019, following the rapid increase of e-cigarette-related or vaping-associated lung injury (
EVALI) in young people, which resulted in the critical care admission of thousands of teenagers and young adults. Pulmonary functional imaging is well-positioned to provide information about the acute and chronic effects of vaping. We generated a systematic review to retrieve relevant imaging studies that describe the acute and chronic imaging findings that underly vaping-related lung structure-function abnormalities.
UNASSIGNED: A systematic review was undertaken on June 13th, 2023 using PubMed to search for published manuscripts using the following criteria: [(\"Vaping\" OR \"e-cigarette\" OR \"
EVALI\") AND (\"MRI\" OR \"CT\" OR \"Imaging\")]. We included only studies involving human participants, vaping/e-cigarette use, and MRI, CT and/or PET.
UNASSIGNED: The search identified 445 manuscripts, of which 110 (668 unique participants) specifically mentioned MRI, PET or CT imaging in cases or retrospective case series of patients who vaped. This included 105 manuscripts specific to CT (626 participants), three manuscripts which mainly used MRI (23 participants), and two manuscripts which described PET findings (20 participants). Most studies were conducted in North America (n = 90), with the remaining studies conducted in Europe (n = 15), Asia (n = 4) and South America (n = 1). The vast majority of publications described case studies (n = 93) and a few described larger retrospective or prospective studies (n = 17). In e-cigarette users and patients with
EVALI, key CT findings included ground-glass opacities, consolidations and subpleural sparing, MRI revealed abnormal ventilation, perfusion and ventilation/perfusion matching, while PET showed evidence of pulmonary inflammation.
UNASSIGNED: Pulmonary structural and functional imaging abnormalities were common in patients with
EVALI and in e-cigarette users with or without respiratory symptoms, which suggests that functional MRI may be helpful in the investigation of the pulmonary health effects associated with e-cigarette use.