Diverticulitis

憩室炎
  • 文章类型: Journal Article
    教学要点:纵向壁内瘘是憩室炎的罕见并发症,可以通过计算机断层扫描(CT)可视化。
    Teaching point: A longitudinal intramural fistula is a rare complication of diverticulitis that can be visualised by computed tomography (CT).
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  • 文章类型: Journal Article
    比较腹腔镜灌洗和切除手术治疗穿孔憩室炎的长期结果,在瑞典实行了3年的Hinchey三级。
    腹腔镜灌洗已在3项随机对照试验中进行了研究。长期结果表明,与切除相比,灌洗后额外的手术和剩余的造口不太常见,但是需要来自常规护理和更大队列的数据才能获得更完整的图片。
    LapLav是一项全国性队列研究,几乎完全覆盖了2016年至2018年在瑞典进行手术的所有患者。根据疾病和相关健康问题分类-10代码加上手术程序代码的定义,从国家患者登记册中检索该队列。除登记数据外,还审查了所有医疗记录,并检索了数据。倾向评分与逆概率加权用于平衡2组,也就是说,腹腔镜灌洗与切除手术。
    在应用倾向评分之前,该队列由499例患者组成.额外的手术在切除组中更为常见[比值比,0.714;95%置信区间(CI)=0.529-0.962;P=0.0271]。两组之间的死亡率没有差异(风险比,1.20;95%CI=0.69-2.07;P=0.516)。在灌洗组,27%的患者继续进行切除手术。
    在瑞典常规护理中,腹腔镜灌洗手术治疗穿孔憩室炎是安全可行的,Hinchey三级.我们的结果表明,腹腔镜灌洗可用作首选治疗方法。
    UNASSIGNED: To compare long-term outcomes after laparoscopic lavage with resection surgery for perforated diverticulitis, Hinchey grade III as practiced in Sweden for 3 years.
    UNASSIGNED: Laparoscopic lavage has been studied in 3 randomized controlled trials. Long-term results indicate that additional surgery and a remaining stoma are less common after lavage compared with resection, but data from routine care and larger cohorts are needed to get a more complete picture.
    UNASSIGNED: LapLav is a national cohort study with nearly complete coverage of all patients operated in Sweden between 2016 and 2018. The cohort was retrieved from the national patient register by a definition based on the Classification of Diseases and Related Health Problems-10 code plus the surgical procedural code. All medical records have been reviewed and data retrieved in addition to registry data. Propensity score with inverse probability weighting was used to balance the 2 groups, that is, laparoscopic lavage vs resection surgery.
    UNASSIGNED: Before the propensity score was applied, the cohort consisted of 499 patients. Additional surgery was more common in the resection group [odds ratio, 0.714; 95% confidence interval (CI) = 0.529-0.962; P = 0.0271]. Mortality did not differ between the groups (hazard ratio, 1.20; 95% CI = 0.69-2.07; P = 0.516). In the lavage group, 27% of patients went on to have resection surgery.
    UNASSIGNED: In Swedish routine care, laparoscopic lavage was feasible and safe for the surgical treatment of perforated diverticulitis, Hinchey grade III. Our results indicate that laparoscopic lavage can be used as a first-choice treatment.
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  • 文章类型: Journal Article
    目的:这项工作的目的是研究左结肠憩室炎患者术后早期吻合口漏或盆腔脓肿(AL/PA)与症状性吻合口狭窄(SAS)之间的关系。
    方法:这是一项由FrançaisedeChirurgie协会进行的全国性憩室炎手术患者队列研究的回顾性研究。使用路径分析进行评估。该数据库包括7053名接受结肠憩室炎手术的患者,选择性或在紧急情况下进行手术,通过开放式或腹腔镜检查。从研究分析中排除存在(i)右侧憩室炎的患者(初始数据库包括所有连续接受结肠憩室炎手术的患者),(ii)在第一次手术期间未进行吻合或(iii)缺少有关狭窄的信息,术后脓肿或吻合口漏。
    结果:在纳入最终分析的4441例患者中,327例(4.6%)发生AL/PA,82例(1.8%)发生SAS。AL/PA是与SAS发生风险相关的独立因素(OR=3.41,95%CI=1.75-6.66)。与分流造口≥100天的情况一样(OR=2.77,95%CI=1.32-5.82),而肠系膜下动脉近端中心血管结扎与风险降低相关(OR=0.41;95%CI=0.19~0.88).造口分流<100天或≥100天也是与AL/PA风险相关的因素(OR=3.08,95%CI=2-4.75,OR=12.95,95%CI=9.11-18.50)。有趣的是,AL/PA和SAS的放射引流或手术治疗之间没有显著关联.
    结论:AL/PA是与SAS风险相关的独立因素。AL/PA的治疗与吻合口狭窄的发生无关。分流造口与AL/PA和SAS的风险增加相关。特别是如果它被放置≥100天。医生必须了解这些信息,以便在择期或紧急手术期间创建造口时决定最佳行动方案。
    OBJECTIVE: The aim of this work was to investigate the association between early postoperative anastomotic leakage or pelvic abscess (AL/PA) and symptomatic anastomotic stenosis (SAS) in patients after surgery for left colonic diverticulitis.
    METHODS: This is a retrospective study based on a national cohort of diverticulitis surgery patients carried out by the Association Française de Chirurgie. The assessment was performed using path analyses. The database included 7053 patients operated on for colonic diverticulitis, with surgery performed electively or in an emergency, by open access or laparoscopically. Patients were excluded from the study analysis where there was (i) right-sided diverticulitis (the initial database included all consecutive patients operated on for colonic diverticulitis), (ii) no anastomosis was performed during the first procedure or (iii) missing information about stenosis, postoperative abscess or anastomotic leakage.
    RESULTS: Of the 4441 patients who were included in the final analysis, AL/PA occurred in 327 (4.6%) and SAS occurred in 82 (1.8%). AL/PA was a significant independent factor associated with a risk for occurrence of SAS (OR = 3.41, 95% CI = 1.75-6.66), as was the case for diverting stoma for ≥100 days (OR = 2.77, 95% CI = 1.32-5.82), while central vessel ligation proximal to the inferior mesenteric artery was associated with a reduced risk (OR = 0.41; 95% CI = 0.19-0.88). Diverting stoma created for <100 days or ≥100 days was also a factor associated with a risk for AL/PA (OR = 3.08, 95% CI = 2-4.75 and OR = 12.95, 95% CI = 9.11-18.50). Interestingly, no significant association between radiological drainage or surgical management of AL/PA and SAS could be highlighted.
    CONCLUSIONS: AL/PA was an independent factor associated with the risk for SAS. The treatment of AL/PA was not associated with the occurrence of anastomotic stenosis. Diverting stoma was associated with an increased risk of both AL/PA and SAS, especially if it was left for ≥100 days. Physicians must be aware of this information in order to decide on the best course of action when creating a stoma during elective or emergency surgery.
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  • 文章类型: Journal Article
    背景术语“憩室”是指在胃肠道中存在憩室,但主要位于乙状结肠,用于描述结肠憩室病。憩室,它们是大肠壁上的囊状突起,在全球变得越来越普遍,在发达国家和发展中国家。这种发生率的增加主要归因于饮食和生活方式的变化。提高公众意识可能有助于降低该疾病及其相关并发症的发病率。目的本研究旨在评估沙特阿拉伯人群中有关憩室炎及其危险因素的知识和意识水平。方法在2024年1月1日至2024年4月1日之间在沙特阿拉伯进行了描述性横断面研究,使用在线问卷调查进行数据收集。目标人群包括18岁至45岁的沙特阿拉伯人,没有憩室炎病史。研究问卷涵盖了参与者的人口统计(西方,中央,南方,东方,北部)地区,知识,憩室炎的认识和实践。结果共有548名符合条件的参与者完成了研究问卷,其中大多数(80.3%;395)来自包括麦加在内的西部地区,麦地那和吉达.参与者年龄从18岁到40岁以上,平均年龄为30.5±11.9岁。与女性相比,男性参与者的比例更高(72.3%),为27.7%。绝大多数研究参与者对憩室炎的知识水平不足(85.9%;471),而只有31(5.7%)对该疾病有足够的知识和认识。报告最多的信息来源包括学习课程(6.4%),媒体(5.3%),和医生(4.7%),而大多数受访者(83.6%)没有来源。结论总之,除了预防策略,目前的研究发现,公众对憩室炎知之甚少,包括其风险因素,临床表现,和诊断过程。公众意识水平的两个重要预测因素是年龄和作为信息来源的医生。
    Background The term \"diverticula\" refers to the existence of diverticula in the gastrointestinal tract but is mainly located in the sigmoid colon and is used to describe colonic diverticulosis. Diverticula, which are sac-like protrusions in the wall of the large bowel, are becoming more prevalent globally, in both developed and developing nations. This increase in occurrence is primarily attributed to changes in dietary and lifestyle patterns. Raising public awareness can potentially contribute to a decrease in the incidence of the disease and its associated complications. Aim This study aims to assess knowledge and awareness levels among the Saudi Arabian population regarding diverticulitis and its risk factors. Methods A descriptive cross-sectional study was conducted in Saudi Arabia between 1st January 2024 to 1st April 2024 using an online questionnaire for data collection. The target population consists of individuals who are between 18 years and 45, in Saudi Arabia without a history of diverticulitis. The study questionnaire covered participants\' demographic (Western, Central, Southern, Eastern, Northern) regions, knowledge, awareness and practice of diverticulitis. Results A total of 548 eligible participants completed the study questionnaire, most of them (80.3%; 395) were from the Western region including Mecca, Medina and Jeddah. Participants\' ages ranged from 18 to more than 40 years with a mean age of 30.5 ± 11.9 years old. A greater percentage (72.3%) of the participants were males compared to the percentage of females, which was 27.7%. The vast majority of the study participants had an inadequate knowledge level about diverticulitis (85.9%; 471) while only 31 (5.7%) had adequate knowledge and awareness about the disease. The most reported sources of information included study courses (6.4%), media (5.3%), and physicians (4.7%) while most respondents (83.6%) had no source. Conclusion In conclusion, aside from preventive strategies, the current study found that the public knew very little about diverticulitis, including its risk factors, clinical presentation, and diagnostic process. The two significant predictors of public awareness level were age and doctors as information sources.
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  • 文章类型: Journal Article
    憩室病患者的治疗仍然具有挑战性。这项全国调查的目的是评估胃肠病学家和全科医生如何使用利福昔明治疗憩室病和憩室病。意大利医院胃肠病学家和内窥镜医师协会(AIGO)和意大利全科医生联合会(FIMMG)的成员被邀请完成一项关于利福昔明在五种临床环境中使用的39项在线调查:(1)憩室病;(2)减轻有症状的并发憩室疾病的症状;(3)减少有症状的非并发憩室病的患者的憩室炎的发生(预防)共有1094名医生完成了调查。总的来说,25.1%,83.5%,68%,74.2%,和63%的医生分别为临床设置1,2,3,4和5开利福昔明.在每种临床环境中,最常用的利福昔明剂量为800毫克/天,最常见的治疗时间是7天,最常用的治疗周期给药(以月表示)为>24个月。这些结果突出表明,需要重新评估利福昔明在憩室和憩室疾病患者中的使用,以减少现有证据与日常临床实践之间的差距。优化医疗资源的使用。
    The management of patients with diverticular disease remains challenging. The aim of this national survey was to assess how gastroenterologists and general practitioners use rifaximin to manage diverticulosis and diverticular disease. Members of the Italian Association of Hospital Gastroenterologists and Endoscopists (AIGO) and the Italian Federation of General Practitioners (FIMMG) were invited to complete a 39-item online survey concerning the use of rifaximin in five clinical settings: (1) diverticulosis; (2) reducing symptoms in symptomatic uncomplicated diverticular disease; (3) reducing the occurrence of diverticulitis in patients with symptomatic uncomplicated diverticular disease (primary prevention); (4) reducing the recurrence of diverticulitis in patients with previous attacks of diverticulitis (secondary prevention); (5) treatment of uncomplicated acute diverticulitis. A total of 1094 physicians completed the survey. Overall, 25.1%, 83.5%, 68%, 74.2%, and 63% of physicians prescribed rifaximin for the clinical settings 1, 2, 3, 4, and 5, respectively. In each clinical setting, the dosage of rifaximin most frequently used was 800 mg/day, the most common duration of therapy was 7 days, and the cyclic administration of treatment (expressed in months) most frequently used was > 24 months. These results highlight that a reappraisal of the use of rifaximin in patients with diverticulosis and diverticular disease is required to reduce the gap between the evidence available and the daily clinical practice, optimizing also the use of healthcare resources.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Journal Article
    背景:机器人手术已在选择性干预中获得广泛接受,然而,它在紧急程序中的作用仍未得到充分探索。虽然2021年WSES立场文件讨论了机器人在急诊普外科中应用的有限研究,它建议严格选择病人,充分的培训,和改进的平台可访问性。这项前瞻性研究旨在定义机器人手术在紧急情况下的作用。评估术中和术后的结果,并评估其可行性和安全性。
    方法:ROEM研究是一项观察性的,prospective,多中心,对临床稳定的成年患者进行机器人手术以紧急治疗包括憩室炎在内的急性病变的国际分析,胆囊炎,和阻塞的疝气。数据收集包括患者人口统计学和干预细节。此外,将收集与手术室团队和使用的手术器械有关的数据,以便进行成本分析。该研究计划从50个参与中心招募至少500名患者,每个中心都有当地的领导和合作者。所有数据将通过运行研究电子数据捕获(REDCap)Web应用程序的安全服务器在线收集和存储。道德考虑和数据治理将是最重要的,需要参与中心的当地道德委员会批准。
    结论:目前的文献和专家共识表明,在适当的支持下,机器人手术在紧急情况下的可行性。然而,挑战包括员工培训,安排与选择性手术的冲突,和增加的成本。ROEM研究旨在提供有关安全性的有价值的数据,可行性,以及紧急情况下机器人手术的成本效益,专注于特定的病理。先前对胆囊炎的研究,腹部疝,和憩室炎提供了对机器人方法的好处和挑战的见解。有必要确定从机器人急诊手术中受益最大的患者群体,以优化结果并证明成本合理。
    Robotic surgery has gained widespread acceptance in elective interventions, yet its role in emergency procedures remains underexplored. While the 2021 WSES position paper discussed limited studies on the application of robotics in emergency general surgery, it recommended strict patient selection, adequate training, and improved platform accessibility. This prospective study aims to define the role of robotic surgery in emergency settings, evaluating intraoperative and postoperative outcomes and assessing its feasibility and safety.
    The ROEM study is an observational, prospective, multicentre, international analysis of clinically stable adult patients undergoing robotic surgery for emergency treatment of acute pathologies including diverticulitis, cholecystitis, and obstructed hernias. Data collection includes patient demographics and intervention details. Furthermore, data relating to the operating theatre team and the surgical instruments used will be collected in order to conduct a cost analysis. The study plans to enrol at least 500 patients from 50 participating centres, with each centre having a local lead and collaborators. All data will be collected and stored online through a secure server running the Research Electronic Data Capture (REDCap) web application. Ethical considerations and data governance will be paramount, requiring local ethical committee approvals from participating centres.
    Current literature and expert consensus suggest the feasibility of robotic surgery in emergencies with proper support. However, challenges include staff training, scheduling conflicts with elective surgeries, and increased costs. The ROEM study seeks to contribute valuable data on the safety, feasibility, and cost-effectiveness of robotic surgery in emergency settings, focusing on specific pathologies. Previous studies on cholecystitis, abdominal hernias, and diverticulitis provide insights into the benefits and challenges of robotic approaches. It is necessary to identify patient populations that benefit most from robotic emergency surgery to optimize outcomes and justify costs.
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  • 文章类型: Journal Article
    这篇综述集中在急性骨盆疼痛的育龄成年人群的初始成像,包括β-人绒毛膜促性腺激素(β-hCG)水平阳性和阴性的患者,怀疑是妇科和非妇科病因。对于所有患者来说,经腹和经阴道盆腔超声与多普勒的组合通常适合作为初始影像学研究。如果怀疑β-hCG阴性患者的非遗传学病因,然后腹部和骨盆的CT有或没有对比通常也是合适的。在β-hCG阳性且怀疑非神经病因学的患者中,腹部和骨盆的CT造影和腹部和骨盆的MRI无造影可能是合适的。在β-hCG阴性和疑似妇科病因的患者中,腹部和骨盆的CT对比,骨盆MRI无造影,或MRI骨盆有和没有对比可能是合适的。美国放射学会适当性标准是针对特定临床状况的循证指南,每年由多学科专家小组审查。指南的制定和修订过程支持对同行评审期刊的医学文献进行系统分析。既定的方法论原则,如建议评估分级,发展,评估或等级适用于评估证据。RAND/UCLA适当性方法用户手册提供了确定特定临床场景的成像和治疗程序适当性的方法。在那些缺乏同行评审文献或模棱两可的情况下,专家可能是制定建议的主要证据来源。
    This review focuses on the initial imaging in the reproductive age adult population with acute pelvic pain, including patients with positive and negative beta-human chorionic gonadotropin (β-hCG) levels with suspected gynecological and nongynecological etiology. For all patients, a combination of transabdominal and transvaginal pelvic ultrasound with Doppler is usually appropriate as an initial imaging study. If nongynecological etiology in patients with negative β-hCG is suspected, then CT of the abdomen and pelvis with or without contrast is also usually appropriate. In patients with positive β-hCG and suspected nongynecological etiology, CT of the abdomen and pelvis with contrast and MRI of the abdomen and pelvis without contrast may be appropriate. In patients with negative β-hCG and suspected gynecological etiology, CT of the abdomen and pelvis with contrast, MRI of pelvis without contrast, or MRI of pelvis with and without contrast may be appropriate. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision process support the systematic analysis of the medical literature from peer reviewed journals. Established methodology principles such as Grading of Recommendations Assessment, Development, and Evaluation or GRADE are adapted to evaluate the evidence. The RAND/UCLA Appropriateness Method User Manual provides the methodology to determine the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where peer reviewed literature is lacking or equivocal, experts may be the primary evidentiary source available to formulate a recommendation.
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  • 文章类型: Journal Article
    空肠憩室病是一种罕见的疾病。大多数时候,它是无症状的;但它可以引起严重的并发症,如肠穿孔,机械闭塞,和出血。
    一位78岁的病人,有生物主动脉瓣假体的历史,心房颤动,2型糖尿病,慢性阻塞性肺病,在急诊科治疗下腹底急性腹痛,恶心,和食欲不振。腹部计算机断层扫描显示下胃部有炎性阻滞,凝集的小肠环,粪便淤滞,和空气夹杂物。怀疑是牵拉性肠系膜和相关的内疝。进行了剖腹探查术,揭示了下胃部的炎症块,其解剖显示内部脓性集合和空肠憩室炎的出现,通过组织病理学检查证实的诊断。空肠分段切除与双层终末肠肠吻合术,灌洗,并进行引流。进化是有利的。
    根据我们的简要回顾,复杂的空肠憩室病的诊断是困难的,有时不能准确地确定,即使是高分辨率成像技术,诊断性剖腹手术对于这些情况是必要的。在出现严重并发症之前,应考虑手术治疗。
    UNASSIGNED: Jejunal diverticulosis is a rare condition. Most of the time, it is asymptomatic; but it can cause severe complications such as intestinal perforation, mechanical occlusion, and hemorrhage.
    UNASSIGNED: A patient aged 78 years, with a history of biological aortic valve prosthesis, atrial fibrillation, type 2 diabetes mellitus, and chronic obstructive pulmonary disease, presented in the emergency department for acute abdominal pain in the lower abdominal floor, nausea, and inappetence. Abdominal computed tomography revealed an inflammatory block in the hypogastrium, agglutinated small intestinal loops, fecal stasis, and air inclusions. Pulled mesentery and associated internal hernia are suspected. Exploratory laparotomy was performed, revealing an inflammatory block in the hypogastrium, whose dissection revealed inner purulent collection and the appearance of jejunal diverticulitis, a diagnosis confirmed by histopathological examination. Segmental resection of the jejunum with double-layer terminal-terminal enteroenteric anastomosis, lavage, and drainage was performed. The evolution was favorable.
    UNASSIGNED: Based on our brief review, the diagnosis of complicated jejunal diverticulosis is difficult and sometimes not accurately established, even by high-resolution imaging techniques, with diagnostic laparotomy being necessary for these situations. Surgical treatment should be considered before severe complications develop.
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  • 文章类型: Journal Article
    随着憩室炎患病率的增加,专业指南鼓励个性化治疗。然而,两位外科医生的治疗偏好频率,和病人,这种偏好对憩室炎管理的影响被低估了。我们回顾了我们机构的3名结直肠外科医生的27例连续患者就诊,以评估推动他们治疗的因素,以及它们对患者随机分为医疗或手术治疗的平衡。使用标准化的访问前和访问后问卷,我们调查了就诊对治疗建议的影响.我们的结果表明,我们的外科医生对复杂疾病有实践偏见,并且偏爱憩室炎的手术治疗,既复杂又不复杂的疾病。这种偏好在门诊就诊后经常没有变化,这对指导真正的共同决策有意义,因为它仍然是建议。
    With the increasing prevalence of diverticulitis, professional guidelines encourage the individualization of treatment. However, the frequency of treatment preferences of both surgeons, and patients, and the resultant impact of that preference on diverticulitis management is underexplored. We reviewed 27 consecutive patient visits of 3 colorectal surgeons at our institution to evaluate factors that drove their treatment, as well as their equipoise for patient randomization into medical or surgical treatments. Using standardized pre- and post-visit questionnaires, we investigated the impact of the clinic visit on treatment recommendations. Our results demonstrate that our surgeons have a practice bias towards complicated disease, and have a preference towards operative management of diverticulitis, in both complicated and uncomplicated disease. This preference was frequently unchanged after clinic visit, which has implications for guiding truly shared decision making, as it continues to be the recommendation.
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