目的:GALIPEMIAS是一项旨在确定加利西亚普通人群中家族性血脂异常患病率的研究。本研究的目的是评估动脉粥样硬化血脂异常(AD)的患病率,其与其他心血管风险(CVR)因素的关系,和脂质控制的程度。
方法:在居住在加利西亚的18岁以上的普通人群中进行了横断面研究,并使用了加利西亚卫生服务机构的健康卡(N=1,000)。通过企业集团随机抽样的方式选择样本。分析根据年龄和性别调整后的AD患病率及相关变量。
结果:经年龄和性别调整后的AD患病率为6.6%(95%CI:5.0-8.3%)。动脉高血压,基础血糖改变,2型糖尿病和心血管疾病在AD患者中的发病率高于其他人群.47.5%的AD受试者具有高或非常高的CVR。38.9%(30.5%他汀类药物)的AD参与者(46.1%的高患者和71.4%的CVR非常高的患者)接受了降脂药。25.4%的AD患者有目标LDL-c水平,所有这些都具有低或中等的CVR。
结论:加利西亚成年人群中AD的患病率不容忽视,它与几个CVR因子和心血管疾病有关。尽管如此,这种脂质改变未被诊断和治疗。
OBJECTIVE: GALIPEMIAS is a study designed to establish the prevalence of familial dyslipidemia in the general population of Galicia. The objective of the present study was to assess the prevalence of atherogenic dyslipidemia (AD), its relationship with other cardiovascular risk (CVR) factors, and the degree of lipid control.
METHODS: Cross-sectional study carried out in the general population over 18 years of age residing in Galicia and with a health card from the Galician Health Service (N=1,000). Selection of the sample by means of random sampling by conglomerates. The AD prevalence adjusted for age and sex and the related variables were analyzed.
RESULTS: The prevalence of AD adjusted for age and sex was 6.6% (95% CI: 5.0-8.3%). Arterial hypertension, altered basal glycemia, type 2 diabetes mellitus and cardiovascular disease were more frequent in subjects with AD than in the rest of the population. 47.5% of the subjects with AD had a high or very high CVR. Lipid-lowering drugs were received by 38.9% (30.5% statins) of the participants with AD (46.1% of those with high and 71.4% of those with very high CVR). 25.4% of the subjects with AD had target LDL-c levels, all of them with low or moderate CVR.
CONCLUSIONS: The prevalence of AD in the general adult population of Galicia is not negligible, and it was related to several CVR factors and cardiovascular disease. Despite this, this lipid alteration was underdiagnosed and undertreated.