■颈动脉-海绵窦瘘(CCF)是颈内动脉和/或颈外动脉与海绵窦之间的异常连通。在菲律宾,关于CCF血管内治疗的眼科结果的信息很少。
■本研究旨在描述CCF在我们机构中的临床经验,以进一步了解我们对该疾病的了解。这项研究描述了人口统计概况,危险因素,CCF患者的临床特征,并根据CCF的类型比较患者的数据。该研究讨论了选择不接受血管内治疗的CCF患者的临床特征随时间的变化。该研究还讨论了接受血管内治疗的CCF患者的临床结果,并将其临床结果与未接受血管内治疗的CCF患者进行了比较。
■使用2011年1月至2019年6月临床诊断为CCF的患者的病历回顾进行了回顾性队列研究设计。
■纳入了诊断为CCF的患者的120份医疗记录。根据血管造影结果,根据CCF类型对患者进行分组,第1组或直接CCF中有86名患者,第2组或间接CCF中的23例患者,第3组或混合型CCF11例。患者也根据治疗情况进行分组,A组109名患者,或未接受血管内治疗的患者,B组11名患者,或接受血管内治疗的患者。CCF中男性占主导地位,大多数发生在26至35岁的年龄范围内。CCF的危险因素为创伤和高血压。临床特征包括视力模糊,突增,结膜血管开瓶术,眼外运动受限,复视,听得见的杂音,眼内压升高,和脉动。计算机断层扫描的发现包括扩张的眼上静脉,突增,和扩大的眼外肌肉。直接CCF(第1组)主要发生在男性,平均年龄39.1岁,以创伤为主要危险因素。间接CCF(第2组)主要发生在女性中,平均年龄52.1岁,高血压是主要的危险因素。无论CCF的类型如何,未接受血管内治疗的患者可表现出自发性改善或临床特征恶化.接受血管内治疗的患者通常具有良好的临床结局,表现为功能的改善或没有恶化。与治疗相关的眼科并发症极少。
■血管内治疗在改善视力方面是安全有效的,结膜血管开瓶术,大量的突起,眼外运动受限,复视,和存在的声音。
UNASSIGNED: A carotid-cavernous sinus fistula (CCF) is an abnormal communication between the internal carotid artery and/or the external carotid artery and the cavernous sinus. There is a paucity of information on the ophthalmic outcomes of endovascular treatment for CCF in the Philippines.
UNASSIGNED: This study aimed to describe the clinical experience of CCF in our institution in order to further our understanding of the disease. This study described the demographic profile, risk factors, and clinical features of patients with CCF, and compared the data of patients according to the type of CCF. The study discussed the changes in clinical features over time in CCF patients who chose not to undergo endovascular treatment. The study also discussed the clinical outcomes of CCF patients who underwent endovascular treatment and compared the clinical outcomes to CCF patients who did not undergo endovascular treatment.
UNASSIGNED: A retrospective cohort study design was performed using a medical record review of patients clinically diagnosed with CCF from January 2011 to June 2019.
UNASSIGNED: One hundred twenty medical records of patients diagnosed with CCF were included. Based on angiographic findings, patients were grouped according to type of CCF, with 86 patients in Group 1 or Direct CCF, 23 patients in Group 2 or Indirect CCF, and 11 patients in Group 3 or Mixed type of CCF. The patients were also grouped according to treatment, with 109 patients in Group A, or patients who did not undergo endovascular treatment, and 11 patients in Group B, or patients who underwent endovascular treatment. There was a male predominance in CCF, most occurring in the age range of 26 to 35 years. Risk factors for CCF were trauma and hypertension. Clinical features included the presence of blurring of vision, proptosis, corkscrewing of conjunctival vessels, extraocular movement limitation, diplopia, audible bruit, elevated intraocular pressure, and pulsation. Findings on Computed Tomography scan included dilated superior ophthalmic vein, proptosis, and enlarged extraocular muscles. Direct CCF (Group 1) occurred mostly in males, with mean age of 39.1 years, and with trauma as the major risk factor. Indirect CCF (Group 2) occurred mostly in females, with mean age of 52.1 years, and with hypertension as the major risk factor. Regardless of the type of CCF, patients who did not undergo endovascular treatment can exhibit spontaneous improvement or worsening of clinical features. Patients who underwent endovascular treatment generally had favorable clinical outcomes, manifesting as either improvement or no worsening of features. There were minimal ophthalmic complications associated with treatment.
UNASSIGNED: Endovascular treatment is safe and effective in the improvement of visual acuity, corkscrewing of conjunctival vessels, amount of proptosis, extraocular movement limitation, diplopia, and presence of audible bruit.