背景:目前对SARS-CoV-2感染的医学和社会兴趣很高。这种感染可以,在严重的情况下,伴随着一系列的并发症,如血栓栓塞性疾病或肺实质出血。
方法:本文介绍了两例罕见的由肺实质出血引起的胸腔内大出血,并通过全面抗凝治疗血栓栓塞性疾病而加剧。
结果:在这两种情况下,出血起源于左下叶,危及生命,需要紧急解剖肺切除术-左下肺叶切除术。
结论:抗凝治疗和与COVID-19相关的血栓栓塞事件的组合可导致,在极少数情况下,大量肺出血.在本文描述的两个病例中,这种罕见的并发症被证明是致命的。当出现出血的最初迹象时,必须立即进行适当的反应。
BACKGROUND: The medical and social interest in the SARS-CoV-2 infection is currently high. This infection can, in severe cases, be accompanied by a series of complications, such as thromboembolic disease or pulmonary parenchymal haemorrhage.
METHODS: The paper presents two rare cases of massive intrathoracic haemorrhage caused by pulmonary parenchymal haemorrhage and exacerbated by full anticoagulant treatment of thromboembolic disease.
RESULTS: In both cases, the haemorrhage originated in the left lower lobe and was life threatening, requiring urgent anatomical lung resection - left lower lobectomy.
CONCLUSIONS: The combinaion of anticoagulant therapy and thromboembolic events related to COVID-19 can cause, in rare cases, massive pulmonary haemorrhage. This rare complication proved lethal in one out of two of the cases described in this paper. An imminent and adequate reaction is necessary when the first signs of haemorrhage appear.