Dermoid Cyst

皮样囊肿
  • 文章类型: Case Reports
    幕下脓肿是一种医疗紧急情况。脓肿的常见来源是耳源性病灶,鼻窦炎,或者牙脓肿,很少有先天性缺陷,如皮样囊肿伴鼻窦和脑脊液轴可导致幕下脓肿。此病例报告描述了一个四岁的女孩,脓液从枕骨区域排出。放射学成像显示小脑脓肿,窦道通过枕骨皮质缺损向外开放,伴有阻塞性脑积水。患者接受了神经外科介入治疗,然后进行抗生素治疗。组织样本的组织病理学提示皮样囊肿。先天性缺陷不容忽视。所有新生儿都应该进行彻底的体检,以确定出生缺陷。由于这些缺陷会导致危及生命的并发症,早期识别和早期手术干预是治疗的选择。
    An infratentorial abscess is a medical emergency. Common sources of abscesses are otogenic foci, sinusitis, or dental abscess, rarely congenital defects like dermoid cysts with sinus along with cerebrospinal axis can lead to infratentorial abscess. This case report describes a four-year-old girl with pus discharging from the occipital area. Radiological imaging revealed a cerebellar abscess with the sinus tract open exteriorly through an occipital cortical defect with obstructive hydrocephalus. The patient underwent neurosurgical intervention followed by antibiotic therapy. Histopathology of the tissue sample was suggestive of a dermoid cyst. Congenital defects should not be ignored. All newborns should have a thorough physical examination to identify birth defects. As these defects can cause life-threatening complications, early recognition with early surgical intervention is the treatment of choice.
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  • 文章类型: Case Reports
    盆腔肿块通常起源于盆腔,通常与子宫有关。卵巢,或肠道疾病。本报告描述了我院诊断为腹膜后皮样囊肿的盆腔肿块患者的情况。我们对这个案例进行了分析和文献综述,减少误诊风险,加强腹膜后肿块的治疗。
    Pelvic masses frequently originate from the pelvic cavity and are often associated with uterine, ovarian, or intestinal disorders. This report describes the case of a patient with a pelvic mass diagnosed as a retroperitoneal dermoid cyst at our hospital. We analyzed this case and conducted a literature review, to mitigate the risk of misdiagnosis and enhance the treatment of retroperitoneal masses.
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  • 文章类型: Journal Article
    新生儿是强制性的鼻呼吸器,因此鼻塞是需要评估的非常重要的症状。虽然大多数时候原因都是微不足道的,他们可能会危及生命。出生后立即出现呼吸窘迫,喂养困难,矛盾的紫癜,未能茁壮成长是最明显的症状,和确定单方面或双边参与指导选择性或紧急干预的理由。本研究旨在评估原因,介绍,新生儿鼻塞的处理。我们收集了2003年6月至2023年5月在过去20年中在我院接受鼻塞评估的所有新生儿的数据,并评估了这些病例的诊断和处理策略。在我们的研究中,新生儿鼻塞最常见的原因是后鼻孔闭锁,最罕见的原因是医源性。还报告了各种其他原因。由于新生儿鼻塞有多种罕见原因,每种都有独特的评估和治疗计划。病史采集和临床检查是评估的最重要部分,包括基于办公室的内窥镜评估。影像学研究增加了对解剖阻塞和相关异常(综合征)病例的评估。早期诊断和快速干预可以挽救生命。在取得最佳长期结果时,应强调需要进行后续访问和第二阶段纠正。
    Neonates are obligatory nasal breathers hence nasal obstruction is a very important symptom to be evaluated. Although causes can be trivial most of the time, they can be life-threatening in some. Respiratory distress immediately after birth, feeding difficulties, paradoxical cyanosis, and failure to thrive are the most evident symptoms, and determination of unilateral or bilateral involvement guides the rationale for elective or emergency intervention. This study aimed to evaluate the causes, presentation, and management of neonates with nasal obstruction. We collected the data of all the neonates evaluated for nasal obstruction at our hospital over the past 20 years from June 2003 to May 2023 and assessed the strategy of approach for diagnosis and management of those cases. In our study, the commonest cause for neonatal nasal obstruction was found to be choanal atresia and the rarest was iatrogenic. A variety of other causes were also reported. As neonatal nasal obstruction has a multitude of rare causes each carries a unique assessment and treatment plan. History taking and clinical examination are the most important parts of evaluation including endoscopic evaluation in an office-based setup. Imaging studies add to the evaluation of cases of anatomical obstructions and associated anomalies (syndromes). Early diagnosis and swift intervention can be life-saving. The need for follow-up visits and second-stage corrections should be emphasized in getting the best long-term results.
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    文章类型: Journal Article
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  • 文章类型: Journal Article
    Dermoid nasal cysts (congenital nasal median heterotopias) are a rare congenital pathology in children.
    OBJECTIVE: Yo consider the clinical picture, methods of radiation diagnosis and to study the surgical results of a dermoid cyst of the nose according to the literature.
    METHODS: A retrospective review of medical histories with the diagnosis of \"Dermoid cyst of the back of the nose and nasal cavity, epidermal cyst of the back of the nose, glioma, encephalocele\" was conducted from 2017 to 2022 in the Pediatric Otorhinolaryngological Department of the National Medical Research Center for Otorhinolaryngology of the Federal Medical-Biological Agency of Russia. The case histories were analyzed by the nature of the lesion, the imaging techniques performed, the course of the operation and the results obtained.
    METHODS: A total of 16 medical histories were analyzed, the average age was 4.5 years (range 10 months - 15 years), over the past 5 years with a diagnosis of \"Dermoid cyst of the nasal dorsum and nasal cavity, glioma, epidermal cyst of the nasal dorsum, encephalocele\". All patients underwent magnetic resonance imaging (MRI) in the preoperative period, 14 patients also underwent computed tomography (CT).
    RESULTS: Of these, 7 had a confirmed dermoid cyst with a fistula, 3 patients without a fistula, 3 patients had glioma, and 1 had encephalocele, 2 patients had an epidermoid cyst. A fistulous opening of the dermoid cyst of the nasal dorsum and nasal cavity was observed in the upper third of the nasal dorsum in 3 children, in the middle third in 2 patients and in the lower third in 2 children. The article presents a scheme for the characteristics of the lesion and the tactics of surgical treatment in comparison with the data of foreign authors. Intraoperatively, intracranial spread occurred in 6 patients. Various surgical approaches for intracranial proliferation and a corresponding literature review are also presented. Catamnestic follow-up ranged from 1 to 5 years (on average, 3.5 years), no relapses or postoperative complications were noted.
    CONCLUSIONS: Nasal median heterotopias are a rare congenital anomaly. Preoperative preparation should include CT and MRI to assess the lesion and exclude intracranial spread. The surgical approach depended directly on the localization of heterotopia and its spread. All patients had a good cosmetic result after the surgical treatment performed by us according to the author\'s method.
    Дермоидные кисты носа (врожденные назальные срединные гетеротопии) являются редкой врожденной патологией у детей.
    UNASSIGNED: Проанализировать клиническую картину, методы лучевой диагностики и изучить результаты хирургического лечения врожденных назальных гетеротопий у детей в течение последних 5 лет.
    UNASSIGNED: Проведен ретроспективный обзор историй болезни с диагнозом «дермоидная киста спинки носа и полости носа, эпидермальная киста спинки носа, глиома, энцефалоцеле» с 2017 по 2022 г. в детском оториноларингологическом отделении ФГБУ «НМИЦО ФМБА России». Истории болезни проанализированы по характеру поражения, выполненным методам визуализации, ходу операции и полученным результатам. Всего проанализированы 16 историй болезни за последние 5 лет с диагнозом «дермоидная киста спинки носа и полости носа, глиома, эпидермальная киста спинки носа, энцефалоцеле», средний возраст пациентов составил 4,5 года (диапазон 10 мес — 15 лет). Всем пациентам выполнена в предоперационном периоде магнитно-резонансная томография, 14 пациентам — также компьютерная томография.
    UNASSIGNED: У 7 пациентов подтверждена дермоидная киста со свищевым ходом, у 3 — без свищевого хода, у 3 — глиома, у 1 — энцефалоцеле, у 2 — эпидермоидная киста. Свищевое отверстие дермоидной кисты спинки носа и полости носа наблюдали в верхней трети спинки носа у 3 детей, в средней трети — у 2, в нижней трети — у 2. Представлена схема характеристики поражения и тактики хирургического лечения в сравнении с данными зарубежных авторов. Интраоперационно интракраниальное распространение имело место у 6 пациентов. Рассмотрены различные хирургические подходы при внутричерепном распространении и представлен соответствующий обзор литературы. Катамнестическое наблюдение составило от 1 до 5 лет (в среднем 3,5 года), рецидивов или послеоперационных осложнений не было.
    UNASSIGNED: Назальные срединные гетеротопии являются редкой врожденной аномалией. Предоперационное обследование должно включать компьютерную томографию и магнитно-резонансную томографию для оценки поражения и исключения внутричерепного распространения. Хирургический подход зависит напрямую от локализации и распространения гетеротопии. У всех пациентов после выполненного нами хирургического лечения по авторской методике наблюдался хороший косметический результат.
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  • 文章类型: Case Reports
    (1)背景:舌下间隙皮样囊肿并不常见,通常表现为无痛,群众逐渐扩大,通常直径不超过3厘米。由于其临床表现,这些囊肿可能类似于各种疾病,在口腔中的发生率相对较低,约占所有皮样囊肿的1.6%。(2)方法:我们介绍了一例17岁的女性,患有累及下颌的巨大皮样囊肿,舌下,和语言区域,几年来未确诊。通过MRI和细针穿刺获得诊断,导致通过子宫颈入路手术切除的决定。(3)结果:愈合过程顺利。手术后的第一天,病人开始了肌功能疗法,成功地恢复了适当的舌头功能。在24个月的随访中,患者保持无症状。(4)结论:宫颈入路可成功治疗累及颌下的巨大口腔皮样囊肿,舌下,和语言空间。手术治疗后,通过肌功能疗法可以成功恢复舌功能。
    (1) Background: Dermoid cysts occurring in the sublingual space are uncommon, typically manifesting as painless, gradually enlarging masses, usually not exceeding 3 cm in diameter. These cysts can resemble various conditions due to their clinical presentation, with a relatively low occurrence rate in the oral cavity, accounting for about 1.6% of all dermoid cysts. (2) Methods: We present the case of a 17-year-old female with a giant dermoid cyst involving the submental, sublingual, and lingual areas, undiagnosed for several years. Diagnosis was achieved through MRI and fine-needle aspiration, leading to the decision for surgical removal through a cervical approach. (3) Results: The healing process was uneventful. From the first day post-surgery, the patient began myofunctional therapy, successfully regaining proper tongue functions. Throughout a 24-month follow-up, the patient remained symptom-free. (4) Conclusions: A cervical approach can successfully treat giant oral dermoid cysts involving submental, sublingual, and lingual spaces. Tongue function can be successfully regained through myofunctional therapy after surgical treatment.
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  • 文章类型: Letter
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  • 文章类型: Case Reports
    卵巢Struma是一种单胚层畸胎瘤,其特征是存在>50%的甲状腺组织。它主要是良性的;因此,术前诊断很重要。它通常表现为多房性囊性肿块,但很少表现为主要的实性肿块。在磁共振成像(MRI)上,在动态钆增强T1加权图像上,实体外观的甲状腺肿显示早期信号强度增强,这在组织病理学上表明甲状腺组织的存在与丰富的血管。卵巢附件报告和数据系统(O-RADS)MRI评分是全球范围内用于表征附件病变的经过验证的分类。基于形态学,信号强度,增强MRI上的任何实体组织,该评分系统可用于将附件病变分为5类,从1分(无附件肿块)到5分(恶性肿瘤高危).在非动态对比增强(非DCE)MRI上注射g(Gd)后30-40秒,其信号强度高于子宫肌层的附件固体肿块的得分为5分(恶性肿瘤的高风险)。在非DCEMRI上注射Gd后30秒,我们提出了一个实性表现为卵巢甲状腺肿的病例,其信号强度高于子宫肌层。术前评分为5分。因此,尽管存在良性卵巢肿块,但仍进行了经腹全子宫切除术和双侧附件卵巢切除术.当在非DCEMRI上Gd注射后30-40秒遇到信号强度高于子宫肌层的附件肿块时,鉴别诊断应包括卵巢甲状腺肿,尽管O-RADSMRI得分为5分,但应该讨论情况的管理。
    Struma ovarii is a monodermal teratoma characterized by the presence of >50% thyroid tissue. It is mostly benign; therefore, preoperative diagnosis is important. It usually manifests as a multilocular cystic mass but rarely as a predominantly solid mass. On magnetic resonance imaging (MRI), solid-appearing struma ovarii showed early signal intensity enhancement on dynamic gadolinium-enhanced T1-weighted images, which histopathologically indicates the presence of thyroid tissue with abundant blood vessels. The Ovarian-Adnexal Reporting and Data System (O-RADS) MRI score is a validated classification worldwide for characterizing adnexal lesions. Based on the morphology, signal intensity, and enhancement of any solid tissue on the MRI, the scoring system can be used to classify adnexal lesions into five categories from score one (no adnexal mass) to score five (high risk of malignancy). An adnexal solid mass with a higher signal intensity than that of the myometrium 30-40 seconds after gadolinium (Gd) injection on non-dynamic contrast-enhanced (non-DCE) MRI was assigned a score of 5 (high risk of malignancy).  We present a case of solid-appearing struma ovarii with a higher signal intensity than that of the myometrium 30 seconds after Gd injection on non-DCE MRI, and it was classified as score five preoperatively. Therefore, a total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed despite the presence of a benign ovarian mass. When an adnexal mass with a higher signal intensity than that of the myometrium 30-40 seconds after Gd injection on non-DCE MRI is encountered, struma ovarii should be included in the differential diagnosis, despite the O-RADS MRI score of five and management of the situation should be discussed.
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  • 文章类型: Journal Article
    背景:胰腺的成熟囊性畸胎瘤或皮样囊肿由于其解剖位置和不断增大的尺寸而使手术方法复杂化。在这里,我们报告了一例巨大的成熟胰腺囊性畸胎瘤,通过完全腹腔镜远端胰腺切除术(LDP)成功切除。
    方法:一名39岁的女性患者被转诊到我们医院进行胰腺肿瘤的评估。三年的随访显示,肿瘤的大小增加到18厘米,在弥散加权磁共振成像中具有高强度固体成分。考虑到恶性肿瘤的可能性,我们决定执行自民党。胶囊看起来足够坚固以承受内窥镜钳的缩回。肿瘤的大小使得难以从尾部到颅侧解剖肿瘤的背侧。胰腺的早期横切和其他端口促进了肿瘤背侧的解剖。我们完成了LDP,术中没有囊肿破裂。在病理检查中,该肿瘤被诊断为起源于胰尾的成熟囊性畸胎瘤。患者于术后第13天出院,无并发症。
    结论:LDP可能是胰腺体或尾部大囊性病变患者的手术选择。术中观察肿瘤和手术细化是完成腹腔镜手术而不发生肿瘤破裂的必要条件。
    BACKGROUND: Mature cystic teratomas or dermoid cysts of the pancreas complicate surgical approaches because of their anatomical position and ever-growing size. Herein, we report a case of a giant mature cystic teratoma of the pancreas that was successfully resected via complete laparoscopic distal pancreatectomy (LDP).
    METHODS: A 39-year-old female patient was referred to our hospital for the evaluation of a pancreatic tumor. Three years of follow-up revealed that the tumor had increased in size to 18 cm, with hyperintense solid components on diffusion-weighted magnetic resonance imaging. Considering the possibility of malignancy, we decided to perform an LDP. The capsule appeared solid enough to withstand the retraction of the endoscopic forceps. Tumor size made it difficult to dissect the dorsal side of the tumor from the caudal to the cranial side. Early transection of the pancreas and additional ports facilitated dissection of the dorsal side of the tumor. We completed the LDP without intraoperative cyst rupture. On pathological examination, the tumor was diagnosed as a mature cystic teratoma originating from the pancreatic tail. The patient was discharged on postoperative day 13 with no complications.
    CONCLUSIONS: LDP may be an option for surgical procedures in patients with large cystic lesions of the pancreatic body or tail. Intraoperative observation of the tumor and surgical refinement are necessary to complete the laparoscopic procedure without tumor rupture.
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  • 文章类型: Case Reports
    背景:与粘液性囊腺癌并存的成熟囊性畸胎瘤是一种罕见的肿瘤,迄今为止很少有病例报道。在这些情况下,良性畸胎瘤恶性转化为腺癌,或者在成熟的囊性畸胎瘤和粘液性肿瘤之间形成碰撞肿瘤,要么主要起源于卵巢的上皮基质表面,或继发于原发性胃肠道肿瘤。对这两种肿瘤进行个体化处理的意义对进一步的治疗管理具有显著的作用。
    方法:在这种情况下,一名33岁伊朗女性的成熟囊性畸胎瘤与粘液性囊腺癌共存于同一卵巢.计算机断层扫描(CT)扫描与左卵巢肿块的额外对比提示畸胎瘤,而切除的卵巢肿块检查报告腺癌伴有囊性畸胎瘤。在手术标本的大体检查中发现了皮样囊肿,并伴有另一个包括粘液样物质的多间隔囊性病变。组织病理学检查显示成熟的囊性畸胎瘤与高分化的粘液性囊腺癌有关。后者显示CK7-/CK20+免疫谱。由于缺乏临床,放射学,以及归因于原发性下胃肠道肿瘤的生化发现,免疫谱提出了良性畸胎瘤的腺癌转化的机会。
    结论:此案例显示了大样本的重要性,精确记录粗略的方面,组织病理学检查,免疫组织化学分析,以及放射学和临床结果的帮助,以正确诊断罕见的肿瘤。
    BACKGROUND: Mature cystic teratoma co-existing with a mucinous cystadenocarcinoma is a rare tumor that few cases have been reported until now. In these cases, either a benign teratoma is malignantly transformed into adenocarcinoma or a collision tumor is formed between a mature cystic teratoma and a mucinous tumor, which is either primarily originated from epithelial-stromal surface of the ovary, or secondary to a primary gastrointestinal tract tumor. The significance of individualizing the two tumors has a remarkable effect on further therapeutic management.
    METHODS: In this case, a mature cystic teratoma is co-existed with a mucinous cystadenocarcinoma in the same ovary in a 33-year-old Iranian female. Computed Tomography (CT) Scan with additional contrast of the left ovarian mass suggested a teratoma, whereas examination of resected ovarian mass reported an adenocarcinoma with a cystic teratoma. A dermoid cyst with another multi-septate cystic lesion including mucoid material was revealed in the gross examination of the surgical specimen. Histopathological examination revealed a mature cystic teratoma in association with a well-differentiated mucinous cystadenocarcinoma. The latter showed a CK7-/CK20 + immune profile. Due to the lack of clinical, radiological, and biochemical discoveries attributed to a primary lower gastrointestinal tract tumor, the immune profile proposed the chance of adenocarcinomatous transformation of a benign teratoma.
    CONCLUSIONS: This case shows the significance of large sampling, precise recording of the gross aspects, histopathological examination, immunohistochemical analysis, and the help of radiological and clinical results to correctly diagnose uncommon tumors.
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