自2020年9月以来,SARS-CoV-2变种在全球范围内获得了主导地位,尤其是在肯尼亚,意大利,法国,英国,土耳其,印度尼西亚,印度,芬兰,爱尔兰,新加坡,丹麦,德国,葡萄牙。在这项研究中,我们开发了一个关于28个国家的三角洲变异频率的模型(R2=0.1497),显示在具有123,526单倍型的δ变体的生成期间的突变的遗传。国别单倍型网络显示单倍型在美国的分布(10,174),丹麦(5,637),印度(4,089),德国(2,350),荷兰(1,899),瑞典(1,791),意大利(1,720),法国(1,293),爱尔兰(1,257),比利时(1,207),新加坡(1,193),葡萄牙(1,184)和西班牙(1,133)。我们的分析表明,欧洲单倍型最高,为84%,澳大利亚最低,为0.00001%。用回归线生成散点图模型,该回归线提供估计的突变率,包括每年24.048次替代。我们的研究得出的结论是,delta变异体的全球高患病率是由于感染性的高频率,支持病毒变体的范式转变。
Since September 2020, the SARS-CoV-2 variants have gained their dominance worldwide, especially in Kenya, Italy, France, the UK, Turkey, Indonesia, India, Finland, Ireland, Singapore, Denmark, Germany, and Portugal. In this study, we developed a model on the frequency of delta variants across 28 countries (R2= 0.1497), displaying the inheritance of mutations during the generation of the delta variants with 123,526 haplotypes. The country-wise haplotype network showed the distribution of haplotypes in USA (10,174), Denmark (5,637), India (4,089), Germany (2,350), Netherlands (1,899), Sweden (1,791), Italy (1,720), France (1,293), Ireland (1,257), Belgium (1,207), Singapore (1,193), Portugal (1,184) and Spain (1,133). Our analysis shows the highest haplotype in Europe with 84% and the lowest in Australia with 0.00001%. A model of scatter plot was generated with a regression line which provided the estimated rate of mutation, including 24.048 substitutions yearly. Our study concluded that the high global prevalence of the delta variants is due to a high frequency of infectivity, supporting the paradigm shift of the viral variants.