未经证实:虽然栓塞性卒中占大多数脑梗塞,确定栓塞源的检查不足。非阻塞性普通血管镜检查(NOGA)的发展可以详细观察主动脉的动脉粥样硬化变化。
UNASSIGNED:这项研究的目的是阐明主动脉生成机制在缺血性中风发展中的重要性。
UNASSIGNED:我们连续检查了114例通过NOGA观察到主动脉的患者,这些患者随后接受了脑磁共振成像以检测缺血性卒中病变。在主动脉的评估中,确定自发性主动脉斑块(SRAP)的存在和位置.从起点到弓(近端主动脉[PAo])和近端降主动脉观察到主动脉。
未经证实:114例患者中有49例通过NOGA观察到SRAP。其中,24在PAo有SRAP,43例降主动脉有SRAP。33例患者有缺血性卒中病变,其中6人患有临床神经缺陷.在这些患者中检测到SRAP的频率显著高于81例无缺血性卒中患者(69%vs33%;P<0.01)。SRAP对缺血性卒中的敏感性和特异性分别为0.70和0.68。PAo中SRAP的存在与缺血性卒中显著相关(比值比:14.3;P<0.001)。
未经批准:在缺血性中风的治疗中,应注意SRAP,尤其是在PAO。(STROKE-NOGA[通过非梗阻性全身血管镜检查观察到的自发性动脉斑块破裂是栓塞性STROKE的潜在原因]研究;UMIN000034588)。
UNASSIGNED: Although embolic stroke accounts for most cerebral infarction, examinations to identify the embolic source have been insufficient. Nonobstructive general angioscopy (NOGA) has developed to allow the detailed observation of atheromatous changes of the aorta.
UNASSIGNED: The purpose of this study was to clarify the importance of the aortogenic mechanism in the development of ischemic stroke.
UNASSIGNED: We examined 114 consecutive patients whose aorta was observed by NOGA and who subsequently underwent brain magnetic resonance imaging to detect ischemic stroke lesions. In the evaluation of the aorta, the presence and location of spontaneously ruptured aortic plaque (SRAP) were determined. The aorta was observed from the origin to the arch (proximal aorta [PAo]) and the proximal descending aorta.
UNASSIGNED: Forty-nine of 114 patients had SRAP observed by NOGA. Among these, 24 had SRAP in the PAo, and 43 had SRAP in the descending aorta. Thirty-three patients had ischemic stroke lesions, including 6 with a clinical neurologic deficit. The frequency at which SRAP was detected in these patients was significantly higher in comparison to 81 patients without ischemic stroke (69% vs 33%; P < 0.01). The sensitivity and specificity of the presence of SRAP for ischemic stroke were 0.70 and 0.68, respectively. The presence of SRAP in PAo was significantly correlated with ischemic stroke (odds ratio: 14.3; P < 0.001).
UNASSIGNED: In the treatment of ischemic stroke, attention should be paid to SRAP, especially that in the PAo. (STROKE-NOGA [SponTaneously Ruptured aOrtic plaques as a potential cause of embolic stroKEs visualized by Non-Obstructive General Angioscopy] Study; UMIN000034588).