药理学专家高度重视治疗植物,因为大多数制药公司都依赖药用植物作为原料。因此,使用气相色谱-质谱分析评估了潜在的生物活性成分,并使用DPPH自由基清除活性评估了刺耳各种粗馏分的抗氧化作用。气相色谱-质谱分析显示存在各种生物活性化合物,包括苯二羧酸(18.60%),8-十八烯酸(4.86%),粗甲醇提取物中的11-十八烯酸和10-十八烯酸,1,2-苯二羧酸,二异辛酯(14.42%),1,2-苯二羧酸,单(2-乙基己基)酯(14.42%),6-十八烯酸,甲酯(7.56%),8-十八烯酸,甲酯(7.56%),10-十八烯酸,甲酯(7.56%)和十六烷酸,正己烷提取物中的甲酯(6.55%),乙醛,2-甲基-2-[4-(1-甲基乙基)苯基]-(3.02%),(+)-3-carene,4-异丙烯基-(3.02%),7H-茚并[5,6-b]呋喃-7-酮,4,4a,5,6,7a,8-六氢-(3.02%)和2-[5-(2,2-二甲基-6-亚甲基-环己基)-3-甲基-戊-2-烯基]-[1,4]苯醌(2.79%)在氯仿提取物和1,2-苯二羧酸,单(2-乙基己基)酯(33.005%),1,2-苯二羧酸,在乙酸乙酯萃取物中的二异辛酯(33.005%)和邻苯二甲酸二(2-乙基己基)酯(33.005%)。所有剂量的氯仿级分(43.37-88.65%)以及所有剂量的粗甲醇提取物(36.02-83.75%)均显示出显着的DPPH自由基清除活性。总之,X.spinosum的不同粗馏分可以被认为是药理活性成分的丰富来源,可以对其进行范围分离,并可以进行深入的药理研究。
Pharmacology experts place a high priority on therapeutic plants because the majority of pharmaceutical firms rely on medicinal plants as raw ingredients. Therefore, the potential bioactive components using gas chromatography-mass spectrometry analysis and antioxidant effects using DPPH free radical scavenging activity of various crude fractions of Xanthium spinosum were assessed. Gas chromatography-mass spectrometry analysis showed the presence of various bioactive compounds including benzenedicarboxylic acid (18.60%), 8-octadecenoic acid (4.86%), 11-octadecenoic acid and 10-octadecenoic acid in the crude methanolic extract, 1,2-benzenedicarboxylic acid, diisooctyl ester (14.42%), 1,2-benzenedicarboxylic acid, mono (2-ethylhexyl) ester (14.42%), 6-octadecenoic acid, methyl ester (7.56%), 8-octadecenoic acid, methyl ester (7.56%), 10-octadecenoic acid, methyl ester (7.56%) and hexadecanoic acid, methyl ester (6.55%) in the n-hexane extract, ethanal, 2-methyl-2-[4-(1-methylethyl)phenyl]-(3.02%), (+)-3-carene, 4-isopropenyl-(3.02%), 7H-indeno[5,6-b] furan-7-one, 4,4a,5,6,7a,8-hexahydro- (3.02%) and 2-[5-(2,2-dimethyl-6-methylene-cyclohexyl)-3-methyl-pent-2-enyl]-[1,4] benzoquinone (2.79%) in the chloroform extract and 1,2-benzenedicarboxylic acid, mono (2-ethylhexyl) ester (33.005%), 1,2-benzenedicarboxylic acid, diisooctyl ester (33.005%) and bis(2-ethylhexyl) phthalate (33.005%) in the ethyl acetate extract. Significant DPPH radical scavenging activity was exhibited by the chloroform fraction (43.37-88.65%) at all doses followed by the crude methanolic extract (36.02-83.75%) at all doses. In conclusion, different crude fractions of X. spinosum can be considered a rich source of pharmacologically active components that can be scoped for isolation and may be subjected to in-depth pharmacological study.