目的:寨卡病毒感染与新生儿先天性寨卡综合征(CZS)有关,并以小头畸形为特征,中央/轴向运动和感觉功能障碍,吞咽困难以及之前描述的其他严重健康并发症。CZS通常通过明显/明显的神经发育问题来诊断。尽管有一些CZS颅面/牙列发育的报道,一些临床口腔方面仍然未知。这项研究描述了受CZS影响的儿童的面部和颅骨生长以及乳牙的一些结构和功能特征。
方法:一些头颅,在14名3-5岁的CZS儿童中确定了面部和牙齿特征,并将其与12名按年龄和性别配对的明显健康儿童进行了比较。
结果:14例CZS表现为小头畸形,上颌前颌,改变了面部三分之二,不对称瞳孔线,磨牙症(p=0.006),深前开放咬合与远端蜕膜磨牙关系(p=0.031)。CZS儿童不能自己进食,大多数人不能走路,也没有根据他们的实际年龄发展协调和可理解的语言。相比之下,对照组表现出正常的头骨特征,有自主运动技能,说可理解的语言,自己喂养,表现出和谐的颌间关系,并具有对称的面部三分率。
结论:小头症,吞咽困难,磨牙症,下颌后,面部比例改变和错牙合是CZS的主要颅面和口腔特征。
结论:CZS的并发症,包括与面部和口腔相关的并发症仍在确认中。这项研究揭示了一些颅骨,受CSZ影响的儿童的面部和口腔特征。跨学科康复方案必须解决这些可以改善儿童和父母生活条件的综合征特征。
OBJECTIVE: Zika virus infection has been associated to congenital zika syndrome (CZS) in newborns and is characterized by microcephaly, central/axial motor and sensory dysfunction, dysphagia among other previously described severe health complications. CZS is usually diagnosed postpartum by evident/apparent neural development problems. Although there are some reports of craniofacial/dentition development in CZS, several clinical oral aspects are still unknown. This study describes some structural and functional characteristics of facial and cranial growth and deciduous dentition in CZS-affected children.
METHODS: Some cranial, facial and dental characteristics were determined in 14 children with CZS aged 3-5 years and compared them against 12 apparently healthy children paired by age and gender.
RESULTS: Fourteen CZS cases presented microcephaly, maxillary prognathism, altered facial thirds, asymmetric pupillary line, bruxism (p = 0.006), deep and anterior open bite and distal step decidual molar relationship (p = 0.031). CZS children cannot feed by themselves and most cannot walk and have not develop coordinated and intelligible language according to their chronological age. In contrast, controls presented normal skull features, have autonomous locomotion skills, speak intelligible language, feed by themselves, presented a harmonic intermaxillary relationship and have symmetrical facial thirds.
CONCLUSIONS: Microcephaly, dysphagia, bruxism, mandibular retrognathia, altered facial proportions and malocclusion are the main craniofacial and oral features at CZS.
CONCLUSIONS: The complications of CZS including those related with the face and the oral cavity are still being identified. This study revealed some cranial, facial and oral features in children affected by CSZ. Interdisciplinary rehabilitation protocols must address these syndromic features that could improve children and parents living conditions.