Nurses play key roles in dealing with pandemics yet are often conceived solely as \"technical\" experts without political agency. This study conducts the first global comparative analysis of COVID-19-related protests of nurses and other frontline health workers, with a focus on the first 18 months of the pandemic. We draw on quantitative and qualitative data on nurses\' protests and protest drivers. Results show that such protests were widespread: We identify 3515 events in 90 countries, with several regional hotspots existing. The most common reasons for protests were poor working conditions and insufficient workplace safety, followed by wider social issues like poverty and racism. For most of the time period under consideration, protests demanding access to vaccinations (a rarely explored phenomenon) were more widespread than anti-vaccination events. Protest frequency was highest in countries with high COVID-19-related mortality rates, high levels of human development, and strong social movements at the onset of the pandemic. Recognising the key role of nurses as political actors would help to improve health policies and to maintain a capable healthcare workforce, particularly during acute crises like pandemics.

Nanoparticles have aroused widespread interest because of their unique surface structure and nano effect, which presents novel characteristics like as sound, light, electricity, magnetism, and thermal properties. However, two critical defects have hindered their applications: (1) poor processability resulting from the high melting temperature (e.g., >1000 °C) for some inorganic nanoparticles; (2) the restriction of the nano effect caused by the easy aggregation of the nanoparticles. To solve those issues, solvent-free nanofluids (SNFs) with hard cores and flexible organic chains were successfully designed and fabricated at the beginning of the twenty-first century. The promising technology of SNFs not only solved the dispersion problem of nanomaterials but also imparted novel functionalization to nanoparticles. Up to now, many researchers have been devoted to developing diverse cores and flexible organic polymer chains to endow SNFs with particular functions, such as conductivity, fluorescence, lubricity, and so on. However, there are few review reports on the research progress in the fabrication and applications of functional SNFs. To gain a better understanding of SNFs, this paper presents an overall investigation into the development, fabrication, as well as the applications of functional SNFs.

BACKGROUND: Stroke is the second leading cause of death worldwide. Recent studies have shown that the COVID-19 pandemic has been associated with a higher frequency of stroke. This study aimed to investigate the epidemiologic aspects of stroke two years before and during the COVID-19 pandemic in Kerman.
METHODS: This cross-sectional study was conducted in Kerman. The participants included all patients with a confirmed diagnosis of stroke. COVID-19 confirmation was based on a positive PCR test. The data was analyzed with SPSS.V24 software.
RESULTS: In this study, 4152 patients with stroke were evaluated. The frequency of stroke before and during the COVID-19 pandemic was the same. The total number of stroke patients with COVID-19 was 298 (8.16%). The frequency of ischemic stroke patients before the COVID-19 pandemic was 1751 and during the pandemic was 1770. Before and after the pandemic, the mean age of ischemic stroke patients was 67.42±14.14 and 64.49±14.46 respectively, which showed a statistically significant difference (P>0.001). Our findings showed a significant difference between the NIHSS of ischemic stroke before and after the pandemic (P<0.001). The mortality rate of stroke patients was 111 before COVID-19 and 115 patients in the first two years of COVID-19. Except for the mortality rate (P<0.001), there was no significant difference in other demographic variables between ischemic stroke patients with and without COVID-19.
CONCLUSIONS: The patients with ischemic stroke during the COVID-19 pandemic were younger and had more neurological deficits than the ischemic stroke patients before the pandemic. COVID-19 was associated with higher mortality in patients with ischemic stroke.

Low discovery rates for new antibiotics, commercial disincentives to invest, and inappropriate use of existing drugs have created a perfect storm of antimicrobial resistance (AMR). This \"silent pandemic\" of AMR looms as an immense, global threat to human health. In tandem, many potential novel drug candidates are not progressed due to elevated hydrophobicity, which may result in poor intracellular internalization and undesirable serum protein binding. With a reducing arsenal of effective antibiotics, enabling technology platforms that improve the outcome of treatments, such as repurposing existing bioactive agents, is a prospective option. Nanocarrier (NC) mediated drug delivery is one avenue for amplifying the therapeutic outcome. Here, the performance of several antibiotic classes encapsulated within the lipid-based cubosomes is examined. The findings demonstrate that encapsulation affords significant improvements in drug concentration:inhibition outcomes and assists in other therapeutic challenges associated with internalization, enzyme degradation, and protein binding. We emphasize that a currently sidelined compound, novobiocin, became active and revealed a significant increase in inhibition against the pathogenic Gram-negative strain, Pseudomonas aeruginosa. Encapsulation affords co-delivery of multiple bioactives as a strategy for mitigating failure of monotherapies and tackling resistance. The rationale in optimized drug selection and nanocarrier choice is examined by transport modeling which agrees with experimental inhibition results. The results demonstrate that lipid nanocarrier encapsulation may alleviate a range of challenges faced by antibiotic therapies and increase the range of antibiotics available to treat bacterial infections.

While the second wave of the Covid-19 pandemic is keeping the world on tenterhooks, the last few months have also led to a new wave of cybercrime. The following article analyzes the background and manifestations of pandemic-related cybercrimes and shows how our criminal law systems are able to deal with current challenges in the age of the coronavirus.

UNASSIGNED: The COVID-19 pandemic and the measures taken to combat it led to severe constraints for various areas of life, including mobility. To study the effects of this disruptive situation on the mobility behaviour of entire subgroups, and how they shape their mobility in reaction to the special circumstances, can help to better understand, how people react to external changes.
UNASSIGNED: Aim of the study presented in this article was to investigate to what extent, how and in what areas mobility behaviour has changed during the outbreak of SARS-CoV-2 in Germany. In addition, a focus was put on the comparison of federal states with and without lockdown in order to investigate a possible contribution of this measure to changes in mobility. We asked respondents via an online survey about their trip purposes and trip frequency, their choice of transport mode and the reasons for choosing it in the context of the COVID-19 crisis. For the analyses presented in this paper, we used the data of 4157survey participants (2512 without lockdown, 1645 with lockdown).
UNASSIGNED: The data confirmed a profound impact on the mobility behaviour with a shift away from public transport and increases in car usage, walking and cycling. Comparisons of federal states with and without lockdown revealed only isolated differences. It seems that, even if the lockdown had some minor effects, its role in the observed behavioural changes was minimal.

UNASSIGNED: Novel Corona Virus is a pandemic infectious disease which affects all age groups with higher incidence in geriatric population and chronic diseases. Contact, droplet and airborne had a role for transmission of the disease during airway manoeuvres in infected patients. This study aimed to prepare the operation room and provide protection of both the patient and health care personnel.
UNASSIGNED: This systematic review was conducted according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) protocol. Search engines like Pub Med through HINARI, Cochrane database, Google Scholar to get access for current and updated evidences on operating room team safety and perioperative anesthetic management for patients with suspected or confirmed novel corona virus.
UNASSIGNED: High risk procedures for aerosolization including endotracheal intubation, open lung surgery and airway suctioning should be managed with vented masks.
UNASSIGNED: All health care personnel should wear personal protective equipment based on the class of patients during surgery. Elective procedures should be postponed to save and mobilize resources for the protection and management of the pandemic disease. Emergency procedures including burn, Cesarean section, malignant neoplasia, perforated viscus and traumatic injury should be operated with wearing of personal protective equipment.

As the COVID-19 pandemic lockdowns forced populations across the world to become completely dependent on digital devices for working, studying, and socializing, there has been no shortage of published studies about the possible negative effects of the increased use of digital devices during this exceptional period. In seeking to empirically address how the concern with digital dependency has been experienced during the pandemic, we present findings from a study of daily self-reported logbooks by 59 university students in Copenhagen, Denmark, over 4 weeks in April and May 2020, investigating their everyday use of digital devices. We highlight two main findings. First, students report high levels of online fatigue, expressed as frustration with their constant reliance on digital devices. On the other hand, students found creative ways of using digital devices for maintaining social relations, helping them to cope with isolation. Such online interactions were nevertheless seen as a poor substitute for physical interactions in the long run. Our findings show how the dependence on digital devices was marked by ambivalence, where digital communication was seen as both the cure against, and cause of, feeling isolated and estranged from a sense of normality.

Based on a collaborative endeavor, we present an autoethnographic textual collage of three fictionalized narrative accounts produced as a result of an amalgam of personal experiences encountered during the corona pandemic. The narrative accounts serve as illustrating examples of and critical reflections on how the pandemic and the increased use of digital technologies during the pandemic have affected the experience of reality and (trans)formed thinking and social relations alike. The crisis invites us to reflect on how the current confinement saturated with the ubiquitous presence and influence of digital technologies can be used as an occasion for large-scale reflections.

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