■快速序贯[败血症相关]器官衰竭评估(qSOFA)提示考虑可能的败血症。单个qSOFA元素对严重程度评估和死亡率预测的贡献仍然未知。
■共3974名社区获得性肺炎患者被纳入一项观察性前瞻性队列研究。接收器工作特征曲线下面积(AUROC),赔率比,采用相对风险和Youden指数评估歧视。
■呼吸频率≥22/min显示出最优越的诊断价值,以最大的赔率比表示,相对风险和AUROC,和最大尤登死亡率指数。然而,血压改变和收缩压(SBP)≤100mmHg的指数依次显着下降。呼吸频率≥22/min的预测有效性,改变和SBP≤100mmHg是良好的,足够和贫穷的死亡率,用AUROC表示(分别为0.837、0.734和0.671)。呼吸频率≥22/min显示与SOFA评分的相关性最强,肺炎严重程度指数,住院时间和费用。然而,SBP≤100mmHg与指标的相关性最弱。
■呼吸频率≥22/min对简约qSOFA评估严重程度和预测死亡率的贡献最大。然而,改变的状态和SBP≤100mmHg的贡献依次显着下降。这是第一个已知的前瞻性证据,表明单个qSOFA元素对评估严重程度和预测死亡率的贡献。这可能对更准确的临床分诊决策有影响。
呼吸频率≥22/min显示出最优越的诊断价值。呼吸频率≥22/min显示与严重程度的相关性最强。呼吸频率≥22/min,改变的心理状态和SBP≤100mmHg的死亡率预测良好,足够和糟糕,分别。
UNASSIGNED: The quick sequential [sepsis-related] organ failure assessment (qSOFA) acts as a prompt to consider possible sepsis. The contributions of individual qSOFA elements to assessment of severity and for prediction of mortality remain unknown.
UNASSIGNED: A total of 3974 patients with community-acquired pneumonia were recruited to an observational prospective cohort study. The area under the receiver operating characteristic curve (AUROC), odds ratio, relative risk and Youden\'s index were employed to assess discrimination.
UNASSIGNED: Respiratory rate ≥22/min demonstrated the most superior diagnostic value, indicated by largest odds ratio, relative risk and AUROC, and maximum Youden\'s index for mortality. However, the indices for altered mentation and systolic blood pressure (SBP) ≤100 mm Hg decreased notably in turn. The predictive validities of respiratory rate ≥22/min, altered mentation and SBP ≤100 mm Hg were good, adequate and poor for mortality, indicated by AUROC (0.837, 0.734 and 0.671, respectively). Respiratory rate ≥22/min showed the strongest associations with SOFA scores, pneumonia severity index, hospital length of stay and costs. However, SBP ≤100 mm Hg was most weakly correlated with the indices.
UNASSIGNED: Respiratory rate ≥22/min made the greatest
contribution to parsimonious qSOFA to assess severity and predict mortality. However, the contributions of altered mentation and SBP ≤100 mm Hg decreased strikingly in turn. It is the first known prospective evidence of the contributions of individual qSOFA elements to assessment of severity and for prediction of mortality, which might have implications for more accurate clinical triage decisions.
Respiratory rate ≥22/min demonstrated the most superior diagnostic value.Respiratory rate ≥22/min showed the strongest association with severity.Respiratory rate ≥22/min, altered mentation and SBP ≤100 mm Hg predicted mortality well, adequately and poorly, respectively.