视力障碍和失明带来了重大的全球挑战,常见原因包括年龄相关性黄斑变性,糖尿病,视网膜色素变性,和青光眼。先进的成像工具,比如光学相干层析成像,眼底摄影,光声显微镜,和荧光成像,在改善治疗干预和诊断方法方面发挥着至关重要的作用。造影剂通常与这些工具一起使用以增强图像清晰度和信号检测。本文旨在探讨眼科疾病成像中常用的造影剂。
■评论的第一部分深入研究了先进的眼科成像技术,概述它们在解决愿景相关问题方面的重要性。重点是治疗干预措施和诊断方法的功效,为后续对比剂的探索奠定基础。
■这篇综述的重点是造影剂的作用,特别强调金纳米粒子,特别是金纳米棒。讨论强调了这些造影剂如何优化眼部疾病诊断和监测中的成像,强调其独特的性能,提高信号检测和成像精度。
■最后一节,我们探讨了有机和无机造影剂及其在脉络膜新生血管等特定条件下的应用,视网膜新生血管,和干细胞追踪。该综述通过解决当前造影剂使用的局限性并讨论潜在的未来临床应用来总结。这种全面的探索有助于提高我们对眼部疾病成像中造影剂的理解,并为该领域的进一步研究和开发奠定了基础。
UNASSIGNED: Vision impairment and blindness present significant global challenges, with common causes including age-related macular degeneration, diabetes, retinitis pigmentosa, and glaucoma. Advanced imaging tools, such as optical coherence tomography, fundus photography, photoacoustic microscopy, and fluorescence imaging, play a crucial role in improving therapeutic interventions and diagnostic methods. Contrast agents are often employed with these tools to enhance image clarity and signal detection. This review aims to explore the commonly used contrast agents in ocular disease imaging.
UNASSIGNED: The first section of the review delves into advanced ophthalmic imaging techniques, outlining their importance in addressing vision-related issues. The emphasis is on the efficacy of therapeutic interventions and diagnostic methods, establishing a foundation for the subsequent exploration of contrast agents.
UNASSIGNED: This review focuses on the role of contrast agents, with a specific emphasis on gold nanoparticles, particularly gold nanorods. The discussion highlights how these contrast agents optimize imaging in ocular disease diagnosis and monitoring, emphasizing their unique properties that enhance signal detection and imaging precision.
UNASSIGNED: The final section, we explores both organic and inorganic contrast agents and their applications in specific conditions such as choroidal neovascularization, retinal neovascularization, and stem cell tracking. The review concludes by addressing the limitations of current contrast agent usage and discussing potential future clinical applications. This comprehensive exploration contributes to advancing our understanding of contrast agents in ocular disease imaging and sets the stage for further research and development in the field.