Computer tomography

计算机断层扫描
  • 文章类型: Case Reports
    Omental梗塞是急性腹痛的罕见原因,通常是良性的和自我限制的。梗死的意义在于它可以模仿其他腹部病变,包括阑尾炎,胆囊炎,胰腺炎,或反流病。诊断性腹腔镜检查提供了大网膜梗塞的明确诊断,但它是侵入性的,由于资源有限。当需要非侵入性诊断方法时,腹部和骨盆的计算机断层扫描被认为是诊断网膜梗塞的金标准。此外,超声也可以用于儿童。目前,对影像学证实的网膜梗死患者的诊断和治疗尚无共识.外科医生和放射科医生必须将自发性梗塞网膜视为急性腹痛的罕见原因,因为患者可以通过保守或手术方法获得良好的结果。然而,只有在不可能有替代病理的稳定患者中,才应考虑保守治疗.
    Omental infarction is a rare cause of acute abdominal pain, often benign and self-limiting. The significance of infarction lies in the fact that it can mimic other abdominal pathologies including appendicitis, cholecystitis, pancreatitis, or reflux disease. Diagnostic laparoscopy provides the definitive diagnosis of omental infarction, but it is invasive and limited due to resources. Computed tomography of the abdomen and pelvis has been considered the gold standard to diagnosing omental infarction when a non-invasive diagnostic approach is required. Additionally, ultrasound can also be used alternatively for children. Currently, there is no consensus in the diagnosis and management of patients with imaging-proven omental infarction. Spontaneous infarcted omentum must be considered by surgeons and radiologists as a rare cause of acute abdominal pain as patients can experience good outcomes with either conservative or operative approach. However, conservative management must only be considered in stable patients where alternative pathology is unlikely.
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  • 文章类型: Journal Article
    背景:肺癌是最常见的癌症类型。早期检测肺癌可以降低死亡率。肺结节可能代表早期癌症,可以通过计算机断层扫描(CT)扫描来识别。恶性风险可以根据大小等属性来估计,形状,location,和密度。
    目的:与传统机器学习方法相比,深度学习算法在该领域取得了显着进步。然而,许多现有的基于锚的深度学习算法对预定义的锚盒配置表现出敏感性,需要手动调整以获得最佳结果。相反,当前基于无锚深度学习的结节检测方法通常采用固定大小的结节模型,如立方体或球体。
    方法:为了应对这些技术挑战,我们提出了一种用于肺结节检测的多尺度3D无锚深度学习网络(M3N),利用可调结节建模(ANM)。在这个框架内,ANM以各向异性的方式赋予目标对象的表示能力,设计了一种新颖的点选择策略(PSS)来加速各向异性表示的学习过程。我们进一步合并了一个复合损失函数,该函数结合了传统的L2损失和余弦相似性损失,促进M3N在三个维度上学习结节强度分布。
    结果:实验结果表明,M3N在LUNA16数据集上实现了90.6%的竞争性能指标(CPM),每次扫描有七个预定义的误报。这种性能似乎超过了其他最新的基于深度学习的网络在其各自出版物中报告的性能。个别测试结果还表明,M3N擅长提供更准确的,围绕目标结节轮廓的自适应边界框。
    结论:新开发的结节检测系统减少了对先验知识的依赖,例如数据集中对象的一般大小,因此,它应该增强整体的鲁棒性和通用性。区别于传统的结节建模技术,ANM方法与结节的形态特征更接近。时间消耗和检测结果证明了有希望的效率和准确性,应在临床环境中进行验证。
    BACKGROUND: Lung cancer is the most common type of cancer. Detection of lung cancer at an early stage can reduce mortality rates. Pulmonary nodules may represent early cancer and can be identified through computed tomography (CT) scans. Malignant risk can be estimated based on attributes like size, shape, location, and density.
    OBJECTIVE: Deep learning algorithms have achieved remarkable advancements in this domain compared to traditional machine learning methods. Nevertheless, many existing anchor-based deep learning algorithms exhibit sensitivity to predefined anchor-box configurations, necessitating manual adjustments to obtain optimal outcomes. Conversely, current anchor-free deep learning-based nodule detection methods normally adopt fixed-size nodule models like cubes or spheres.
    METHODS: To address these technical challenges, we propose a multiscale 3D anchor-free deep learning network (M3N) for pulmonary nodule detection, leveraging adjustable nodule modeling (ANM). Within this framework, ANM empowers the representation of target objects in an anisotropic manner, with a novel point selection strategy (PSS) devised to accelerate the learning process of anisotropic representation. We further incorporate a composite loss function that combines the conventional L2 loss and cosine similarity loss, facilitating M3N to learn nodules\' intensity distribution in three dimensions.
    RESULTS: Experiment results show that the M3N achieves 90.6% competitive performance metrics (CPM) with seven predefined false positives per scan on the LUNA 16 dataset. This performance appears to exceed that of other state-of-the-art deep learning-based networks reported in their respective publications. Individual test results also demonstrate that M3N excels in providing more accurate, adaptive bounding boxes surrounding the contours of target nodules.
    CONCLUSIONS: The newly developed nodule detection system reduces reliance on prior knowledge, such as the general size of objects in the dataset, thus it should enhance overall robustness and versatility. Distinct from traditional nodule modeling techniques, the ANM approach aligns more closely with the morphological characteristics of nodules. Time consumption and detection results demonstrate promising efficiency and accuracy which should be validated in clinical settings.
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  • 文章类型: Journal Article
    背景:手臂不规则定位引起的条纹伪影一直是诊断腹部的一个问题。
    目的:通过逐例评估来说明手臂位置不规则的患者在腹部计算机断层扫描(CT)中的误诊风险,并测试是否可以通过人工智能迭代重建(AIIR)算法来解决。
    方法:通过回顾5220例胸、胸腹CT,64例手臂不规则定位患者,除常规混合迭代重建(HIR)外,还使用AIIR重建其图像数据。肝脏病变检测,脾脏,肾脏,胆囊,AIIR图像上的胰腺,由两名放射科医生完成,与HIR图像上的图像进行了比较。AIIR图像引起的差异包括具有其他异常的病例和对先前检测进行校正的病例。对于有差异的情况,发现差异的器官的伪影评分,在两个图像集之间比较了具有差异的囊肿的对比噪声比(CNR)。
    结果:15例发现其他异常:肝硬化(n=2),胆囊结石(n=1),胆囊炎(n=1),额外的脾结节(n=1);额外的肾囊肿(n=8);额外的肝囊肿(3);和额外的脾囊肿(n=1)。纠正脾挫伤1例。AIIR图像上所有涉及的伪影评分均得到改善。受累肝脏的CNRs,肾,脾囊肿改善高达539.7%,538.5%,和245.5%,分别。
    结论:手臂定位不规则可能会导致腹部CT的各种误诊,这几乎是完全可以避免的AIIR算法。
    BACKGROUND: Streak artifacts induced by irregular arm positioning have been an issue in diagnosing the abdomen.
    OBJECTIVE: To illustrate the risk of misdiagnosis in abdominal computed tomography (CT) of patients with irregular arm positioning through a case-by-case evaluation and to test if it can be solved by the artificial intelligence iterative reconstruction (AIIR) algorithm.
    METHODS: By reviewing 5220 cases of chest and thoracoabdominal CT, 64 patients with irregular arm positioning were enrolled, whose image data were reconstructed using AIIR in addition to routine hybrid iterative reconstruction (HIR). Lesion detection for livers, spleens, kidneys, gallbladders, and pancreas on AIIR images, performed by two radiologists, was compared with those on HIR images. Discrepancies arising from AIIR images included both cases with additional abnormalities and those with corrections made on previous detections. For cases with discrepancies, artifact scores for organs where discrepancies were found, and contrast-to-noise ratios (CNRs) of cysts with discrepancies were compared between two image sets.
    RESULTS: Additional abnormalities were detected for 15 cases: additional liver cirrhosis (n=2); additional gallbladder stone (n=1); additional cholecystitis (n=1), additional spleen nodule (n=1); additional kidney cysts (n=8); additional liver cysts (3); and additional spleen cyst (n=1). A spleen contusion was corrected for one case. All involved artifact scores were improved on AIIR images. CNRs of involved liver, kidney, and spleen cysts were improved by up to 539.7%, 538.5%, and 245.5%, respectively.
    CONCLUSIONS: Irregular arm positioning may induce a variety of misdiagnoses in abdominal CT, which is almost totally avoidable by the AIIR algorithm.
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  • 文章类型: Journal Article
    目的:在接受统一CT方案的老年队列中,评估造影后CT对预测中度肝性脂肪变性的诊断表现,利用肝和脾衰减值。
    方法:共有1676名成年人(平均年龄,68.4±10.2年;1045M/631F)接受了CT尿路上皮方案,其中包括未增强,门静脉,以及通过肝脏和脾脏的10分钟延迟期。使用经过验证的深度学习工具执行用于衰减值(在HU中)的自动肝脾分割。未增强的肝脏衰减<40.0HU,对应于>15%基于MRI的质子密度脂肪,作为中度脂肪变性的参考标准。
    结果:中度或重度脂肪变性的患病率为12.9%(216/1676)。门静脉肝HU在预测中度肝脂肪变性方面的诊断性能(AUROC=0.943)明显优于肝脾HU差(AUROC=0.814)(p<0.001)。80和90HU的门静脉期肝阈值对中度脂肪变性的敏感性/特异性为85.6%/89.6%,和94.9%/74.7%,分别,而-40HU和-10HU的肝脾差异的敏感性/特异性为43.5%/90.0%和92.1%/52.5%,分别。此外,中度-重度脂肪变性的肝脏造影后增强显着减少(平均,35.7HUvs47.3HU;p<0.001)。
    结论:仅使用肝脏衰减值,在标准门静脉期CT上可以可靠地诊断中度脂肪变性。考虑脾衰减似乎没有什么价值。中度脂肪变性不仅具有固有的较低的对比前肝脏衰减值(<40HU),但也增强得更少,通常导致80HU或更小的造影后肝脏衰减值。
    结论:仅使用肝脏衰减值,可以在造影后CT上可靠地诊断中度脂肪变性。至少中度脂肪变性的肝脏比轻度或无脂肪变性的肝脏增加少,这与较低的固有衰减相结合,以提高检测。
    结论:常规实践中经常使用肝-脾衰减差异,但似乎具有性能限制。对于中度脂肪变性,肝-脾衰减差异不如肝衰减有效。仅使用肝脏衰减可以在标准门静脉期CT上识别中度和重度脂肪变性。
    OBJECTIVE: To assess the diagnostic performance of post-contrast CT for predicting moderate hepatic steatosis in an older adult cohort undergoing a uniform CT protocol, utilizing hepatic and splenic attenuation values.
    METHODS: A total of 1676 adults (mean age, 68.4 ± 10.2 years; 1045M/631F) underwent a CT urothelial protocol that included unenhanced, portal venous, and 10-min delayed phases through the liver and spleen. Automated hepatosplenic segmentation for attenuation values (in HU) was performed using a validated deep-learning tool. Unenhanced liver attenuation < 40.0 HU, corresponding to > 15% MRI-based proton density fat, served as the reference standard for moderate steatosis.
    RESULTS: The prevalence of moderate or severe steatosis was 12.9% (216/1676). The diagnostic performance of portal venous liver HU in predicting moderate hepatic steatosis (AUROC = 0.943) was significantly better than the liver-spleen HU difference (AUROC = 0.814) (p < 0.001). Portal venous phase liver thresholds of 80 and 90 HU had a sensitivity/specificity for moderate steatosis of 85.6%/89.6%, and 94.9%/74.7%, respectively, whereas a liver-spleen difference of -40 HU and -10 HU had a sensitivity/specificity of 43.5%/90.0% and 92.1%/52.5%, respectively. Furthermore, livers with moderate-severe steatosis demonstrated significantly less post-contrast enhancement (mean, 35.7 HU vs 47.3 HU; p < 0.001).
    CONCLUSIONS: Moderate steatosis can be reliably diagnosed on standard portal venous phase CT using liver attenuation values alone. Consideration of splenic attenuation appears to add little value. Moderate steatosis not only has intrinsically lower pre-contrast liver attenuation values (< 40 HU), but also enhances less, typically resulting in post-contrast liver attenuation values of 80 HU or less.
    CONCLUSIONS: Moderate steatosis can be reliably diagnosed on post-contrast CT using liver attenuation values alone. Livers with at least moderate steatosis enhance less than those with mild or no steatosis, which combines with the lower intrinsic attenuation to improve detection.
    CONCLUSIONS: The liver-spleen attenuation difference is frequently utilized in routine practice but appears to have performance limitations. The liver-spleen attenuation difference is less effective than liver attenuation for moderate steatosis. Moderate and severe steatosis can be identified on standard portal venous phase CT using liver attenuation alone.
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  • 文章类型: Journal Article
    背景:本系统综述(SR)的目的是收集有关使用机器学习(ML)模型诊断颌骨骨内病变的证据,并分析其可靠性,影响,以及这些模型的有用性。该SR根据PRISMA2022指南进行,并在PROSPERO数据库(CRD42022379298)中注册。
    方法:使用首字母缩写PICOS来构造以查询为重点的综述问题“人工智能对于颌骨骨内病变的诊断是否可靠?”在各种电子数据库中进行了文献检索,包括PubMed,Embase,Scopus,科克伦图书馆,WebofScience,丁香花,IEEEXplore,和灰色文学(谷歌学者和ProQuest)。使用PROBAST进行偏倚风险评估,并考虑数据集的任务和采样策略对结果进行了综合。
    结果:纳入了26项研究(21146张射线照相图像)。成釉细胞瘤,牙源性角化囊肿,牙质囊肿,根尖周囊肿是最常见的病变。根据TRIPOD,大多数研究被分类为2型(随机分组).F1评分仅在13项研究中提出,提供了20次试验的指标,平均值为0.71(±0.25)。
    结论:没有确凿的证据支持基于ML的模型在检测中的有用性,分割,颌骨骨内病变的分类和临床常规应用。缺乏关于数据抽样的细节,缺乏一套全面的培训和验证指标,以及缺乏外部测试极限实验,阻碍了对模型性能的正确评估。
    BACKGROUND: The purpose of this systematic review (SR) is to gather evidence on the use of machine learning (ML) models in the diagnosis of intraosseous lesions in gnathic bones and to analyze the reliability, impact, and usefulness of such models. This SR was performed in accordance with the PRISMA 2022 guidelines and was registered in the PROSPERO database (CRD42022379298).
    METHODS: The acronym PICOS was used to structure the inquiry-focused review question \"Is Artificial Intelligence reliable for the diagnosis of intraosseous lesions in gnathic bones?\" The literature search was conducted in various electronic databases, including PubMed, Embase, Scopus, Cochrane Library, Web of Science, Lilacs, IEEE Xplore, and Gray Literature (Google Scholar and ProQuest). Risk of bias assessment was performed using PROBAST, and the results were synthesized by considering the task and sampling strategy of the dataset.
    RESULTS: Twenty-six studies were included (21 146 radiographic images). Ameloblastomas, odontogenic keratocysts, dentigerous cysts, and periapical cysts were the most frequently investigated lesions. According to TRIPOD, most studies were classified as type 2 (randomly divided). The F1 score was presented in only 13 studies, which provided the metrics for 20 trials, with a mean of 0.71 (±0.25).
    CONCLUSIONS: There is no conclusive evidence to support the usefulness of ML-based models in the detection, segmentation, and classification of intraosseous lesions in gnathic bones for routine clinical application. The lack of detail about data sampling, the lack of a comprehensive set of metrics for training and validation, and the absence of external testing limit experiments and hinder proper evaluation of model performance.
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  • 文章类型: Journal Article
    这份简短的报告旨在展示光子计数技术以及标准的颅骨成像协议在患者的颅骨计算机断层扫描中可视化分流阀的实用性。回顾性调查了具有颅骨协议的光子计数CT扫描,并遇到了四种类型的分流阀:proGAV2.0®,M.blue®,CodmanCertas®,和proSA®。将这些扫描与相同患者在不同时间点从非光子计数扫描仪获得的扫描进行比较。对这些发现的分析表明,光子计数技术可用于清晰,精确地可视化分流阀,而无需任何额外的辐射或特殊的重建模式。与其他CT探测器相比,提供了出色的空间分辨率,从而突出了光子计数的增强实用性。该技术有助于更准确地表征分流阀,并且可以支持细微异常的检测和分流阀的精确评估。
    This brief report aimed to show the utility of photon-counting technology alongside standard cranial imaging protocols for visualizing shunt valves in a patient\'s cranial computed tomography scan. Photon-counting CT scans with cranial protocols were retrospectively surveyed and four types of shunt valves were encountered: proGAV 2.0®, M.blue®, Codman Certas®, and proSA®. These scans were compared with those obtained from non-photon-counting scanners at different time points for the same patients. The analysis of these findings demonstrated the usefulness of photon-counting technology for the clear and precise visualization of shunt valves without any additional radiation or special reconstruction patterns. The enhanced utility of photon-counting is highlighted by providing superior spatial resolution compared to other CT detectors. This technology facilitates a more accurate characterization of shunt valves and may support the detection of subtle abnormalities and a precise assessment of shunt valves.
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  • 文章类型: Journal Article
    这项研究提供了光子计数探测器(PCCT)和能量集成探测器(EID)之间的颅骨计算机断层扫描(CT)成像质量和辐射剂量的客观比较。我们回顾性分析了76例患者的158例CT扫描,在同一个体上使用两种检测器类型以确保一致的比较。我们的分析集中在计算机断层扫描剂量指数和剂量长度乘积以及脑灰质和白质的对比度噪声比和信噪比上。我们利用标准化的成像协议和一致的患者定位来最小化变量。PCCT显示出更高的图像质量和更低的辐射剂量的潜力,正如这项研究所强调的那样,从而在减少辐射暴露的情况下实现诊断清晰度,强调其在病人护理中的重要性,特别是对于需要多次扫描的患者。结果表明,虽然这两个系统都是有效的,PCCT在神经放射学评估中提供了增强的成像和患者安全性。
    This study provides an objective comparison of cranial computed tomography (CT) imaging quality and radiation dose between photon counting detectors (PCCTs) and energy-integrated detectors (EIDs). We retrospectively analyzed 158 CT scans from 76 patients, employing both detector types on the same individuals to ensure a consistent comparison. Our analysis focused on the Computed Tomography Dose Index and the Dose-Length Product together with the contrast-to-noise ratio and the signal-to-noise ratio for brain gray and white matter. We utilized standardized imaging protocols and consistent patient positioning to minimize variables. PCCT showed a potential for higher image quality and lower radiation doses, as highlighted by this study, thus achieving diagnostic clarity with reduced radiation exposure, underlining its significance in patient care, particularly for patients requiring multiple scans. The results demonstrated that while both systems were effective, PCCT offered enhanced imaging and patient safety in neuroradiological evaluations.
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  • 文章类型: Journal Article
    深度学习(DL)需要大量的训练数据来提高性能并防止过拟合。为了克服这些困难,我们需要增加训练数据集的大小。这可以通过在小数据集上增强来完成。增强方法必须在学习期间增强模型的性能。有几种类型的变换可以应用于医学图像。这些转换可以应用于整个数据集或数据的子集,取决于预期的结果。在这项研究中,我们将数据增强方法分为四组:缺失增强,没有修改的地方;基本的增强,其中包括亮度和对比度调整;中间增强,包含更广泛的转换,如旋转,翻转,以及除了亮度和对比度调整之外的移动;以及高级增强,其中使用所有转换层。我们计划进行全面分析,以确定应用于脑CT图像时哪个组表现最佳。此评估旨在确定在提高模型准确性方面产生最有利结果的增强组,最大限度地减少诊断错误,并在脑CT图像分析的背景下保证模型的鲁棒性。
    Deep learning (DL) requires a large amount of training data to improve performance and prevent overfitting. To overcome these difficulties, we need to increase the size of the training dataset. This can be done by augmentation on a small dataset. The augmentation approaches must enhance the model\'s performance during the learning period. There are several types of transformations that can be applied to medical images. These transformations can be applied to the entire dataset or to a subset of the data, depending on the desired outcome. In this study, we categorize data augmentation methods into four groups: Absent augmentation, where no modifications are made; basic augmentation, which includes brightness and contrast adjustments; intermediate augmentation, encompassing a wider array of transformations like rotation, flipping, and shifting in addition to brightness and contrast adjustments; and advanced augmentation, where all transformation layers are employed. We plan to conduct a comprehensive analysis to determine which group performs best when applied to brain CT images. This evaluation aims to identify the augmentation group that produces the most favorable results in terms of improving model accuracy, minimizing diagnostic errors, and ensuring the robustness of the model in the context of brain CT image analysis.
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  • 文章类型: Case Reports
    尽管栓塞现在被认为是PAVM的首选治疗方法,如果畸形涉及大血管,可以考虑手术干预。
    Despite embolization being now considered the preferred treatment for PAVM, surgical intervention may be considered if the malformation involves large vessels.
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  • 文章类型: Journal Article
    教学要点:合成大麻素是近年来使用量明显增加的药物,其毒理作用不容忽视。这些物质可能引起的慢性炎症过程,如血管炎,在所有年龄段都会造成严重的健康问题。
    Teaching Point: Synthetic cannabinoids are drugs whose use has increased significantly in recent years and whose toxicological effects cannot be ignored. Chronic inflammatory processes such as vasculitis that may be caused by these substances pose serious health problems at all ages.
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