一名77岁的妇女因与复视相关的单眼眼睑水肿而被转诊。轨道磁共振成像显示,在右眼眶的内侧上部有眼眶肿块,没有任何眶内受累。活检显示结节性淋巴瘤,具有1-2级混合滤泡(60%)和大细胞成分。肿瘤块用低剂量放射治疗(2分4Gy)治疗,复视在一周内完全消失。在2年的随访中,患者完全缓解.据我们所知,这是首例通过首次低剂量放射治疗治疗的混合成分滤泡型和大成分眼眶淋巴瘤.
A 77-year-old woman was referred for a one-eyed palpebral edema associated with diplopia. An orbit magnetic resonance imaging showed an orbital mass in the superior medial portion of the internal right orbit without any intraorbital involvement. Biopsies demonstrated a nodular lymphoma with mixed follicular grade 1-2 (60%) and large cell components. The tumor mass was treated with a low-dose radiation therapy (4Gy in 2 fractions) with a complete disappearance of diplopia within one week. At 2-year follow-up, patient was in complete remission. To the best of our knowledge, this is the first case of mixed component follicular and large components orbital lymphoma managed by first-intent low-dose radiation therapy.