背景:越来越多的证据表明,运动训练对患有先天性心脏病的人有有益的影响。这些发现主要来自于小的,在门诊康复设施中进行的单中心运动试验.近年来,通过数字通信技术(远程康复)远程提供运动干预措施已经增加。然而,迄今为止,很少有研究对先天性心脏病患者进行远程康复的功效。
目的:评估远程医疗运动干预对有先天性心脏病手术双心室修复史的人的影响。
方法:将从四个澳大利亚地点招募100名患有复杂的双心室先天性心脏病的合格青少年(≥16岁)和成年参与者,并随机分为(1)16周远程健康提供的中等至剧烈强度的联合(有氧和阻力)运动训练计划或(2)常规护理(对照组)。在1:1的分配中,8个月的随访。
方法:主要结果将是有氧能力的变化,以峰值摄氧量(VO2peak)表示。次要结果将包括血管功能的变化,肌肉氧合,代谢概况,身体成分和肌肉骨骼健康,神经激素激活,神经认知功能,身体活动水平,饮食和营养状况,和生活质量。结果将在基线时进行评估,16周,和12个月(以确定长期维护潜力)。
结论:如果发现有效,远程康复可能是提供锻炼的另一种选择,改善健康结果,并增加锻炼方案的可及性。需要功效数据来量化这种锻炼方式的临床意义。
背景:ACTRN12622000050752试用注册日期:2022年1月17日试用注册网址:https://www。anzctr.org.au/Trial/Registration/TrialReview.aspx?id=382635&showOriginal=true&isReview=true试验注册表名称:澳大利亚和新西兰临床试验注册表。
BACKGROUND: Accumulated evidence suggests that exercise training exerts beneficial effects on people with congenital heart conditions. These findings are predominantly derived from small, single-centre exercise trials conducted in outpatient rehabilitation facilities. In recent years, the delivery of exercise interventions remotely has increased through digital communications technology (telerehabilitation). However, very little research to date has been conducted into the efficacy of telerehabilitation in people with a congenital heart condition.
OBJECTIVE: To evaluate the effects of a telehealth-delivered exercise intervention in people with a history of a surgical biventricular repair due to a congenital heart condition.
METHODS: One hundred eligible adolescent (≥ 16 years) and adult participants living with a complex biventricular congenital heart condition will be recruited from four Australian sites and randomised to either (1) a 16-week telehealth-delivered combined (aerobic and resistance) exercise training programme of moderate-to-vigorous intensity or (2) usual care (control group), in a 1:1 allocation, with an 8-month follow-up.
METHODS: The primary outcome will be the change in aerobic capacity expressed as peak oxygen uptake (VO2peak). Secondary outcomes will include changes in vascular function, muscle oxygenation, metabolic profile, body composition and musculoskeletal fitness, neurohormonal activation, neurocognitive function, physical activity levels, dietary and nutritional status, and quality of life. Outcomes will be assessed at baseline, 16 weeks, and 12 months (to determine longer-term maintenance potential).
CONCLUSIONS: If found to be efficacious, telerehabilitation may be an alternative option for delivering exercise, improving health outcomes, and increasing accessibility to exercise programmes. Efficacy data is required to quantify the clinical significance of this delivery mode of exercise.
BACKGROUND: ACTRN12622000050752 Trial registration date: 17 January 2022 Trial registration URL: https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=382635&showOriginal=true&isReview=true Trial registry name: Australian and New Zealand Clinical Trials Registry.