Clinical diagnostic tests

临床诊断试验
  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    室性心动过速(VT)是一种罕见但可能致命的妊娠并发症。我们介绍了一例孕妇由于频繁的室性早搏(PVC)和源自左心室流出道的VT而导致的心肌病。在妊娠晚期晚期出现后,由于室性心动过速持续发作,我们决定在药物滴定4天后分娩胎儿.交货后,患者在出院后数月仍有频繁的PVCs和VT,她最终接受了PVC消融术,大大减轻了PVC负担,改善了心肌病。怀孕心脏团队的多学科计划导致了适当的应急计划和成功的分娩。此案例强调了多学科管理是妊娠并发VT的最佳实践,以及在妊娠中需要更好的PVC诱发心肌病诊断指南。
    Ventricular tachycardia (VT) is a rare but potentially fatal complication in pregnancy. We present a case of a pregnant woman with cardiomyopathy due to frequent premature ventricular complexes (PVCs) and VT originating from the left ventricular outflow tract. After presenting late in the third trimester, the decision was made to deliver the fetus after 4 days of medication titration due to continued sustained episodes of VT. After delivery, the patient continued to have frequent PVCs and VT several months after discharge, and she ultimately underwent a PVC ablation with dramatic reduction in PVC burden and improvement in cardiomyopathy. Multidisciplinary planning with a pregnancy heart team led to appropriate contingency planning and a successful delivery. This case highlights how multidisciplinary management is best practice in pregnancy complicated by VT and the need for better diagnostic guidelines for PVC-induced cardiomyopathy in the setting of pregnancy.
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  • 文章类型: Case Reports
    支气管囊肿是罕见的先天性病变,主要见于纵隔。大多数患者无症状,可以进行微创切除治疗。我们介绍了一例中年患者,该患者因心悸和呼吸急促而被送往地区综合医院。她接受了计算机断层肺血管造影检查,显示可能是支气管囊肿,随后被转移到我们医院。她在入院期间出现心房颤动,需要使用β受体阻滞剂和地高辛治疗。心脏MRI显示左心房后方有一个大囊肿,中度环状心包积液和双侧胸腔积液。有明显的左心房压迫。患者接受了囊肿的手术切除并出院。她在一周内因心悸返回医院,并接受静脉抗生素治疗脓毒症。一周后她出院并保持临床稳定。
    Bronchogenic cysts are rare congenital lesions found primarily in the mediastinum. Most patients are asymptomatic and can be treated with minimally invasive resection. We present a case of a middle-aged patient who presented to a district general hospital with palpitations and shortness of breath. She underwent a computerised tomographic pulmonary angiogram that showed a likely bronchogenic cyst and was subsequently transferred to our hospital. She developed atrial fibrillation during admission requiring therapy with beta-blockers and digoxin. Cardiac MRI revealed a large cyst posterior to the left atrium, a moderate circumferential pericardial effusion and bilateral pleural effusions. There was significant left atrial compression. The patient underwent surgical removal of the cyst and was discharged. She returned to the hospital within a week with palpitations and was treated with intravenous antibiotics for sepsis. She was discharged a week later and remained clinically stable.
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  • 文章类型: Case Reports
    登革热是一种病毒性疾病,临床上表现为发烧,最严重形式的血小板减少相关出血并发症和休克。这位40多岁的女性患者主要以完全房室传导阻滞的晕厥发作向心脏中心急诊科就诊。临时心脏起搏作为紧急程序有助于维持心律和血流动力学。最近发作的发烧史帮助我们怀疑并通过血清学证实了登革热病理。2天后恢复正常窦性心律,我们取消了临时起搏.随访6个月无心律失常复发。登革热相关心律失常的病因仍未确定。在发烧恢复阶段,完全性心脏传导阻滞可能是紧急情况下的主要表现。其及时诊断和临时起搏可允许自发恢复。将心电图纳入登革热患者指南应有助于临床医生决定其治疗方法。
    Dengue is a viral disease that clinically presents with fever, thrombocytopenia-related haemorrhagic complications and shock in its severest form. This female patient in her 40s primarily presented to the emergency department of the cardiac centre as syncopal attacks with a complete atrioventricular block. Temporary cardiac pacing as an emergency procedure helped to maintain cardiac rhythm and haemodynamics. A history of recent onset fever helped us to suspect and confirmed by serology for dengue pathology. Normal sinus rhythm was restored after 2 days, and we removed the temporary pacing. Cardiac arrhythmia did not recur in 6 months of follow-up. The aetiology for dengue-related cardiac arrhythmia is still not established. In the recovery phase from fever, complete heart block may show up as a primary presentation in the emergency. Its timely diagnosis and temporary pacing may allow spontaneous recovery. The inclusion of electrocardiography in dengue patient guidelines should help clinicians to dictate its treatment.
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  • 文章类型: Case Reports
    冠状动脉瘘很少见,但它是最常见的冠状动脉异常之一。大多数病例在年轻患者中无症状,除非它很大且具有血液动力学意义。血栓栓塞并发症的发生率通常随年龄增长而增加。我们报告了一例20多岁的年轻男性,表现为中央胸痛。冠状动脉计算机断层造影显示,由于右冠状动脉和右心房之间的瘘被血栓阻塞,导致急性冠状动脉综合征。在与冠状动脉和先天性心脏多学科团队讨论后,大家一致认为,我们应该对他进行保守的抗凝和抗血小板治疗,以及包括重复心脏成像在内的3个月随访策略.一年后,他的抗凝和抗血小板药物停药.
    Coronary arterial fistulae are rare, but it is one of the most common coronary artery anomalies. Most of the cases are asymptomatic in younger patients unless it is large and of haemodynamic significance. The incidence of thromboembolic complications usually increases with age. We report a case of a young male in his early 20s presenting with central chest pain. Coronary computed tomographic angiography revealed acute coronary syndrome due to a fistula between right coronary artery and right atrium occluded by thrombus. After discussion with coronary and congenital heart multidisciplinary team, a consensus was agreed that we should manage him conservatively with anticoagulant and antiplatelet therapy and a 3-month follow-up strategy that included repeating cardiac imaging. After a year, his anticoagulation and antiplatelet medication was discontinued.
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  • 文章类型: Case Reports
    在流行病学上通常被称为“消失的神秘”,心内膜心肌纤维化(EMF)仍然是非洲和印度次大陆某些地区限制性心肌病的最常见原因,它被认为是一个重大的公共卫生问题。另一方面,在发达国家,这被认为是一种罕见的现象。由于缺乏靶向治疗,该实体被认为是无法治愈的,即使在它被发现75年后。作者在这里描述了一个印度男性的案例,在他30岁出头的时候,他在很少的日常活动中出现呼吸困难的抱怨,两腿肿胀和腹部丰满3个月。临床特征提示孤立性右心衰竭。超声心动图诊断为EMF,心脏MRI证实。患者已发展为双心室功能障碍,并且由于目前尚无靶向治疗方案,因此正在用利尿剂对症治疗。
    Often termed as \'vanishing mystery\' epidemiologically, endomyocardial fibrosis (EMF) continues to be the the most common cause of restrictive cardiomyopathy in Africa and some parts of the Indian subcontinent, where it is considered a significant public health problem. On the other hand, in developed countries, it is considered a rare phenomenon. This entity is considered incurable due to lack of targeted therapies, even after 75 years since its discovery. The authors describe here a case of an Indian male, in his early 30s who presented with complaints of dyspnoea on minimal daily activities, swelling of both legs and abdominal fullness for 3 months. The clinical features were suggestive of isolated right heart failure. He was diagnosed with EMF on echocardiography and the findings were confirmed on cardiac MRI. The patient has progressed to develop biventricular dysfunction and is being managed symptomatically with diuretics due to unavailability of targeted treatment options at present.
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  • 文章类型: Case Reports
    一名40多岁的男性患者,有肾结石病史,在沙漠中发现10天后没有口服,因严重脱水入院,急性肾损伤和横纹肌溶解。他在住院期间出现急性意识丧失,并伴有新的左侧偏瘫和偏瘫。排除出血后,及时溶栓。他后来胸痛,变得低血压。超声心动图显示心包积液和升主动脉扩张,怀疑夹层。脑和颈部的磁共振血管造影术报告了右颈内动脉分水岭分布和夹层的双侧枕枕区域。CT血管造影显示A型主动脉夹层从升主动脉延伸到双侧髂总动脉。溶栓逆转,患者接受了升主动脉置换术,在外部设施重新悬吊主动脉瓣和主动脉弓脱支,完全恢复。
    A male patient in his 40s with a history of nephrolithiasis and found in the desert after 10 days without oral intake was admitted to the hospital for severe dehydration, acute kidney injury and rhabdomyolysis. He had acute-onset loss of consciousness during hospitalisation with new left-sided hemiparesis and hemineglect. After haemorrhage was excluded, prompt thrombolysis was given. He later had chest pain and became hypotensive. An echocardiogram revealed pericardial effusion and dilation of the ascending aorta with suspected dissection. Magnetic resonance angiography of the brain and neck reported bilateral parieto-occipital areas of stroke in a watershed distribution and dissection of the right internal carotid artery. CT angiography showed type A aortic dissection from the ascending aorta extending into the bilateral common iliac arteries. Thrombolysis was reversed and the patient underwent ascending aorta replacement, resuspension of the aortic valve and aortic arch debranching at outside facility with complete recovery.
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  • 文章类型: Case Reports
    我们介绍了一例70多岁的高热患者,该患者在超声心动图上被发现具有孤立的天然肺动脉瓣植被,血培养上的粪肠球菌.值得注意的是,我们的患者没有与之前在少数病例报告中描述的这种罕见形式的心内膜炎相关的典型危险因素.
    We present a case of a febrile patient in his 70s who was found to have isolated native pulmonary valve vegetations on echocardiography, and Enterococcus faecalis on blood cultures. Of note, our patient had none of the typical risk factors associated with this rare form of endocarditis previously described in only a handful of case reports.
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  • 文章类型: Case Reports
    Kounis综合征是一种罕见的急性冠状动脉综合征(ACS),由于过敏或过敏反应而发生。Kounis综合征可以由包括抗生素在内的各种药物引起,质子泵抑制剂,抗高血压药物,皮质类固醇,和抗肿瘤药物。此外,先前文献报道了与兰索拉唑和泮托拉唑相关的Kounis综合征病例.在这份报告中,我们介绍了一例与奥美拉唑使用相关的Kounis综合征,并讨论高怀疑指数的必要性,因为它经常被低估。
    Kounis syndrome is a rare type of acute coronary syndrome (ACS) that occurs as a result of an allergic or anaphylactic reaction. Kounis syndrome can be induced by various medications including antibiotics, proton pump inhibitors, antihypertensive medications, corticosteroids, and antineoplastic medications. Additionally, cases of Kounis syndrome associated with lansoprazole and pantoprazole have been previously reported in the literature. In this report, we present a case of Kounis syndrome associated with omeprazole use, and discuss the need for a high index of suspicion as it is often underrecognised.
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  • 文章类型: Case Reports
    一个男孩在儿童早期出现心脏骤停。根据标准儿科复苏指南,在医院外和急诊科提供护理。尽管心肺复苏后最初恢复了自发循环,两次除颤电击和肾上腺素通过骨内通路,他反复发作无脉室性心动过速和室颤。总的来说,进行了40次除颤电击,他随后稳定了静脉注射艾司洛尔的联合治疗,胺碘酮和米力农.他被转移到儿科重症监护病房,并在出院前插入了自动植入式心脏复律除颤器。基因检测已经证实了儿茶酚胺能多形性室性心动过速的诊断,并且假设儿童兴奋在一年中的一个流行时间,加上含咖啡因的饮料,他最初的心脏骤停是由医源性肾上腺素传播的。从那以后他一直保持稳定,到目前为止,没有神经后遗症,没有明显延长的停机时间。
    A boy in early childhood presented in cardiac arrest. Care was provided out of hospital and in the emergency department as per standard paediatric resuscitation guidelines. Despite initial return of spontaneous circulation following cardiopulmonary resuscitation, two defibrillation shocks and epinephrine via intraosseous access, he had recurrent episodes of pulseless ventricular tachycardia and ventricular fibrillation. In total, 40 defibrillation shocks were administered, and he subsequently stabilised on combined treatment with intravenous esmolol, amiodarone and milrinone. He was transferred to the paediatric intensive care unit and had an automated implantable cardioverter-defibrillator inserted prior to discharge. Genetic testing has confirmed a diagnosis of catecholaminergic polymorphic ventricular tachycardia and it is hypothesised that the childhood excitement at a popular time of year, combined with caffeinated drinks, instigated his initial cardiac arrest which was propagated with iatrogenic epinephrine. He has remained stable since, with no neurological sequelae thus far from a significantly prolonged downtime.
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