Clavicle

锁骨
  • 文章类型: Journal Article
    在法医年龄估计中,锁骨的CT成像用于确定完成21岁以上的年龄。如果锁骨内侧骨phy骨化完全,年轻人被认为超过21岁。这项研究的目的是检查统计参数(特异性,预测概率)为特征“锁骨内侧骨化完成”。285名男性患者,出于各种原因,2019年12月1日至2022年12月6日在弗莱堡大学医学中心接受胸部CT检查,其中203名患者被纳入研究。根据Schmeling将锁骨骨化的阶段分为1-5阶段。虽然71名21岁以下的患者中有70名被正确估计为21岁以下,有一名患者的一侧骨化被分类为4期,因此估计其年龄超过21岁.如果只包括双方骨化阶段相同的受试者,测试方法的特异性为100%,阳性预测概率为100%。如果还包括仅一侧为第4阶段的患者,特异性为98.6%。因此,在标准化的薄层CT中,只有两个锁骨的完全和对称的骨化(根据Schmeling分类的第4阶段)可以被归类为年轻男性年龄超过21岁的可靠指标.在内侧锁骨不对称骨化的情况下(一侧未达到阶段4),可能会出现假阳性评估和年龄超过21岁的错误假设。
    In forensic age estimation, CT imaging of the clavicles is used to determine an age over completed 21 years. If ossification of the medial clavicular epiphysis is complete, young men are assumed to be over 21 years of age. The aim of this study is to check the statistical parameters (specificity, predictive probability) for the characteristic \"completed ossification of the medial clavicles\". 285 male patients who, for various reasons, received a chest CT at the Medical Center of the University of Freiburg between 1st December 2019 and 6th December 2022 were screened for the study, of whom 203 patients were included in the study. The stage of clavicular ossification was classified as stage 1 - 5 according to Schmeling. While 70 out of 71 patients under 21 years of age were correctly estimated to be under 21 years of age, there was one patient whose ossification on one side was classified as stage 4 and who would therefore have been estimated to be over 21 years of age. If only subjects whose ossification stage was the same on both sides are included, the specificity of the test method is 100% and the positive predictive probability is 100%. If patients for whom only one side is stage 4 are also included, the specificity is 98.6%. Thus, only the complete and symmetrical ossification of both clavicles (stage 4 according to the Schmeling classification) in a standardised thin-layer CT can be classified as a reliable indicator of an age over 21 years in young men. In the case of asymmetric ossification of the medial clavicles (stage 4 is not reached on one side), false positive evaluations and the incorrect assumption of an age over 21 years can occur.
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  • 文章类型: Journal Article
    UNASSIGNED: Determine the reliability of three different methods of evaluating bone shortening in displaced midshaft clavicle fractures (DCMF).
    UNASSIGNED: A cross-sectional analytical study evaluated bone shortening by metric tape (MT), radiography (X-ray), and computed tomography (CT). Twenty-six men had been evaluated and used clavícula not broken as control. The collection of data was of the blind type for three specialists. Differences and reliability were analyzed with the Friedman and Kappa tests and validated with the T-test (CI: 95%; significance index p<0.05; Software \"R\" version 3.2.2).
    UNASSIGNED: The MT measurements (control) showed abnormal distribution and significant statistical difference concerning the imaging tests (p=0.000008). There was a similarity between X-ray and CT and Kappa agreement of 0.65. The fractured clavicles presented similar measurements between the three methods (p=0.059), and the T-tests proved that the similarity was caused by chance or possible measurement errors.
    UNASSIGNED: Measurement by metric tape showed a tendency to overestimate bone shortening. The CT showed more reliable results for the diagnosis; however, the X-ray was sufficient for decision-making by surgeons, and therefore, it is not possible to rule out the importance of this resource for DCMF. Level of Evidence IV; Case-Control Study.
    UNASSIGNED: Determinar a confiabilidade de três diferentes métodos de avaliação do encurtamento ósseo em fraturas deslocadas do eixo médio da clavícula (FDEMC).
    UNASSIGNED: Estudo analítico transversal que avaliou o encurtamento ósseo por fita métrica (FM), radiografia (X-Ray) e tomografia computadorizada (TC). Foram avaliados 26 homens utilizando a clavícula não fraturada como controle. A coleta de dados foi do tipo cega por três especialistas. As diferenças e a confiabilidade foram analisadas com os testes de Friedman e Kappa e validados com o teste T (IC:95%; índice de significância p<0,05; Software \"R\" versão 3.2.2).
    UNASSIGNED: As medidas de FM (controle), apresentaram distribuição anormal e diferença estatísfica significativa em relação aos exames de imagem (p=0,000008). Houve semelhança entre radiografia e TC, concordância Kappa 0,65. As clavículas fraturadas apresentaram medidas semelhantes entre os três métodos (p=0,059) e os testes-T comprovaram que a semelhança foi provocada casualmente ou possíveis erros de medição.
    UNASSIGNED: A medição por fita métrica apresentou tendência em superestimação do encurtamento ósseo. A TC apresentou resultados mais confiáveis para o diagnóstico, contudo, a radiografia foi suficiente para tomada de decisão dos cirurgiões e por isso, não é possível descartar a importância deste recurso para FDEMC. Nível de Evidência IV; Estudo Caso Controle.
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  • 文章类型: Journal Article
    背景:在医学成像中,基于深度学习的语义分割算法与预处理技术的集成可以减少对人类注释的需求并推进疾病分类。在已建立的预处理技术中,对比度有限的自适应直方图均衡(CLAHE)已经证明了在各种模态中改进分割算法的功效。如X射线和CT。然而,考虑到数据集的异质性和不同解剖结构的各种对比,仍然需要改进的对比增强方法。
    方法:本研究提出了一种新的预处理技术,ps-KDE,研究其对深度学习算法在前后胸部X线片中分割主要器官的影响。Ps-KDE通过基于所有图像的归一化频率替换像素值来增强图像对比度。我们在U-Net架构上评估了我们的方法,并在ImageNet上预先训练了ResNet34骨干。训练五个独立的模型来分割心脏,左肺,右肺,左锁骨,和右锁骨.
    结果:使用ps-KDE训练来分割左肺的模型获得了0.780(SD=0.13)的Dice评分,而接受CLAHE训练的Dice得分为0.717(SD=0.19),p<0.01。ps-KDE似乎也更健壮,因为基于CLAHE的模型在左肺模型的选择测试图像中对右肺进行了错误分类。执行ps-KDE的算法可在https://github.com/wyc79/ps-KDE获得。
    结论:我们的结果表明,当分割某些肺区域时,ps-KDE比当前的预处理技术具有优势。这在随后的分析如疾病分类和风险分层中可能是有益的。
    BACKGROUND: In medical imaging, the integration of deep-learning-based semantic segmentation algorithms with preprocessing techniques can reduce the need for human annotation and advance disease classification. Among established preprocessing techniques, Contrast Limited Adaptive Histogram Equalization (CLAHE) has demonstrated efficacy in improving segmentation algorithms across various modalities, such as X-rays and CT. However, there remains a demand for improved contrast enhancement methods considering the heterogeneity of datasets and the various contrasts across different anatomic structures.
    METHODS: This study proposes a novel preprocessing technique, ps-KDE, to investigate its impact on deep learning algorithms to segment major organs in posterior-anterior chest X-rays. Ps-KDE augments image contrast by substituting pixel values based on their normalized frequency across all images. We evaluate our approach on a U-Net architecture with ResNet34 backbone pre-trained on ImageNet. Five separate models are trained to segment the heart, left lung, right lung, left clavicle, and right clavicle.
    RESULTS: The model trained to segment the left lung using ps-KDE achieved a Dice score of 0.780 (SD = 0.13), while that of trained on CLAHE achieved a Dice score of 0.717 (SD = 0.19), p<0.01. ps-KDE also appears to be more robust as CLAHE-based models misclassified right lungs in select test images for the left lung model. The algorithm for performing ps-KDE is available at https://github.com/wyc79/ps-KDE.
    CONCLUSIONS: Our results suggest that ps-KDE offers advantages over current preprocessing techniques when segmenting certain lung regions. This could be beneficial in subsequent analyses such as disease classification and risk stratification.
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  • 文章类型: Case Reports
    胸锁后关节的创伤性脱位是一种严重的损伤,可能会出现严重的并发症,因此必须格外小心。我们报告了一例年轻男性,锁骨内侧后脱位,并压迫头臂动脉和食道。进行了切开复位和钢丝环扎术的放置,术后效果良好。
    The traumatic dislocation of the posterior sternoclavicular joint is a serious injury with possibly severe complications and therefore has to be managed with the greatest caution. We report the case of a young male with a posterior dislocation of the medial clavicle with compression of the brachiocephalic artery as well as the esophagus. Open reduction and placement of a wire cerclage were performed with a good postoperative outcome.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    背景:本研究的目的是探讨使用正交桥系统(OBS)的新型髓内固定技术治疗锁骨中段骨折的疗效。
    方法:本研究共纳入63例患者:35例接受钢板内固定(LP组),28例接受OBS髓内固定(OBS组)。手术时间,术中失血,切口长度,骨折愈合时间,去除内固定剂,肩痛的视觉模拟量表(VAS)评分,比较两组患者Constant-Murley肩关节评分及并发症发生情况。
    结果:术前一般数据,比如性,年龄和骨折类型,两组间差异无统计学意义(P>0.05)。然而,OBS组在手术时间方面表现出比LP组更好的结果,术中出血量和总切口长度(P<0.05)。此外,OBS组骨折愈合时间和内固定摘除时间明显短于LP组(P<0.05)。OBS组术后第1天、第1周、第1个月和第3个月的VAS评分均低于LP组(P<0.05)。此外,术后1、3、6个月时,OBS组的Constant-Murley肩关节评分均高于LP组(P<0.05),术后1年无显著性差异(P>0.05)。OBS组患者均未出现手术切口瘢痕,LP组6例患者出现手术切口瘢痕。最后,OBS组的并发症发生率低于LP组。
    结论:对于锁骨中段骨折,OBS髓内固定比锁定钢板内固定更好,因为它导致更少的创伤。更快的恢复,更好的疗效,以及更好的美学效果和舒适度。因此,该技术作为锁骨中段骨折的新型治疗方法有潜力.
    方法:III,回顾性观察性研究。
    BACKGROUND: The aim of this study was to explore the efficacy of a novel intramedullary fixation technique using the ortho-bridge system (OBS) for midshaft clavicle fractures.
    METHODS: A total of 63 patients were included in this study: 35 underwent plate internal fixation (LP group) and 28 underwent OBS intramedullary fixation (OBS group). Surgical time, intraoperative blood loss, incision length, fracture healing time, removal of the internal fixation agent, visual analog scale (VAS) score for shoulder pain, Constant-Murley shoulder score and complication occurrence were compared between the two groups.
    RESULTS: Preoperative general data, such as sex, age and fracture type, were not significantly different between the two groups (P > 0.05). However, the OBS group exhibited better outcomes than the LP group exhibited in terms of surgical time, intraoperative blood loss and total incision length (P < 0.05). Additionally, the OBS group exhibited a significantly shorter fracture healing time and internal-fixation removal time than the LP group exhibited (P < 0.05). The VAS scores on postoperative day 1, week 1, month 1 and month 3 were lower in the OBS group than in the LP group (P < 0.05). Furthermore, the Constant-Murley shoulder scores at 1, 3, and 6 months postoperatively were higher in the OBS group than in the LP group (P < 0.05), with no significant difference at 1 year after surgery (P > 0.05). None of the patients in the OBS group experienced scarring of the surgical incision, and 6 patients in the LP group experienced scarring of the surgical incision. Finally, the complication incidence in the OBS group was lower than that in the LP group.
    CONCLUSIONS: For midshaft clavicle fractures, OBS intramedullary fixation is better than locking-plate internal fixation because it led to less trauma, a faster recovery, better efficacy, and better esthetic outcomes and comfort. Therefore, this technique may have potential as a novel treatment for midshaft clavicle fractures.
    METHODS: III, retrospective observational study.
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  • 文章类型: Journal Article
    本文探讨了肉毒杆菌神经毒素在通过暂时性肌肉麻痹帮助骨折恢复中的作用。具体来说,它研究了肉毒杆菌神经毒素引起的胸锁乳突肌麻痹对大鼠锁骨骨折的影响。该研究旨在评估安全性,有效性,以及对骨折愈合的影响。健康雄性白化Wistar大鼠分为四组:锁骨骨折,肉毒神经毒素注射液,两者,和控制。手术是在麻醉下进行的,术后,动物被监测28天。随后进行安乐死和放射学评估,检查骨折愈合和肌肉变化,而组织进行组织病理学评估。改良Lane-Sandhu评分系统用于锁骨骨折的影像学评估,结果从完全愈合到骨不连。骨折后28天的组织病理学检查显示纤维组织,间充质细胞,和所有组的原始愈伤组织形成。尽管愈伤组织成分各不相同,肉毒杆菌神经毒素的给药不影响锁骨愈合,与对照组相似的分数证明了这一点。一些研究已经探索了肉毒杆菌神经毒素在骨折恢复中的应用。研究表明,它有可能增强某些类型骨折的功能恢复。理论上的好处包括控制肌肉痉挛,辅助还原技术,防止不愈合。然而,应考虑肉毒神经毒素的短暂作用和非普遍应用。本研究发现,与对照组相比,肉毒杆菌毒素在愈合方面没有明显的优势,而组织学评估显示对肌肉组织有潜在的不良影响。进一步的研究对于了解其风险收益平衡和长期影响至关重要。
    This paper explores the role of botulinum neurotoxin in aiding fracture recovery through temporary muscle paralysis. Specifically, it investigates the effects of botulinum neurotoxin-induced paralysis of the sternocleidomastoid muscle on clavicle fractures in rats. The research aims to assess safety, effectiveness, and the impact on fracture healing. Healthy male Albino Wistar rats were divided into four groups: clavicle fracture, botulinum neurotoxin injection, both, and control. Surgeries were conducted under anaesthesia, and postoperatively, animals were monitored for 28 days. Euthanasia and radiological assessment followed, examining fracture healing and muscle changes, while tissues were histopathologically evaluated. The modified Lane-Sandhu scoring system was used for the radiographic evaluation of clavicle fractures, and the results varied from complete healing to nonunion. Histopathological examination at 28 days postfracture showed fibrous tissue, mesenchymal cells, and primary callus formation in all groups. Despite varied callus compositions, botulinum neurotoxin administration did not affect clavicle healing, as evidenced by similar scores to the control group. Several studies have explored botulinum neurotoxin applications in fracture recovery. Research suggests its potential to enhance functional recovery in certain types of fractures. Theoretical benefits include managing muscle spasticity, aiding reduction techniques, and preventing nonunion. However, botulinum neurotoxin\'s transient effect and nonuniversal applications should be considered. The present study found that botulinum toxin had no clear superiority in healing compared to controls, while histological evaluation showed potential adverse effects on muscle tissue. Further research is essential to understand its risk-benefit balance and long-term effects.
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  • 文章类型: Journal Article
    顽固性锁骨骨不连是一个不常见但具有挑战性的问题。由于复杂性和供体发病率,血管化的骨重建不是一线治疗。尽管它在特定情况下具有实用性。对Embase和Medline数据库进行了系统评估,以了解锁骨骨不连的股骨内侧髁重建病例。十项研究被纳入,包括26名患者。平均年龄为38.9岁。男性10例,女性16例。干预前骨不连的平均时间为37.79个月;股骨内侧髁皮瓣后的平均愈合时间为7.60个月。两名患者未实现结合。在先前至少有一次植骨固定失败的11例患者中,考虑到当前的“黄金标准”,9名患者(81.81%)继续实现联合,而2例患者(18.19%)没有。5例患者有6例报告并发症。股骨内侧髁皮瓣是治疗顽固性锁骨骨不连的一种有价值的选择。
    Recalcitrant clavicular nonunion is an uncommon but challenging problem. Vascularized bone reconstruction is not first-line therapy due to complexity and donor morbidity, though it has utility in select cases. A systematic review of Embase and Medline databases was undertaken for cases of medial femoral condyle reconstruction for clavicle nonunion. Ten studies met inclusion, encompassing 26 patients. Mean age was 38.9 years. Ten patients were male and 16 female. Mean time of nonunion was 37.79 months prior to intervention; mean time to union following medial femoral condyle flap was 7.60 months. Two patients did not achieve union. Of the 11 patients who previously had at least one failed fixation with bone graft, considered the current \"gold standard\", 9 patients (81.81%) went on to achieve union, while 2 patients (18.19%) did not. There were six reported complications in five patients. Medial femoral condyle flap is a valuable option in recalcitrant clavicle nonunion.
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  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    目标:我们为非编程医生创建了无代码机器学习(NML)平台的基础架构,以创建NML模型。我们通过创建NML模型来对X射线照片进行分类以确定锁骨骨折的存在与否来测试平台。
    方法:我们的IRB批准的回顾性研究包括2039例患者的4135例锁骨X光片(平均年龄52±20岁,F:M1022:1017)来自13家医院。每位患者都有两视锁骨X光片,带有轴向和前后投影。X线片阳性的锁骨骨折移位或非移位。我们将NML平台配置为通过DICOM对象的Web访问,使用医院虚拟网络档案中的系列唯一标识自动检索合格考试。平台训练模型,直到验证损失平台。一旦测试完成,该平台提供了接收机工作特性曲线和混淆矩阵,用于估计灵敏度,特异性,和准确性。
    结果:NML平台成功检索了3917张射线照片(3917/4135,94.7%),并对其进行了解析,以便在训练中创建具有2151张射线照片的ML分类器,100张用于验证的射线照片,和测试数据集中的1666张X光照片(772张锁骨骨折的X光照片,894无锁骨骨折)。该网络以90%的灵敏度识别锁骨骨折,87%的特异性,和88%的准确性,AUC为0.95(置信区间0.94-0.96)。
    结论:NML平台可以帮助医生从多中心成像数据集创建和测试机器学习模型,例如我们研究中根据锁骨骨折的存在对X射线照片进行分类的模型。
    OBJECTIVE: We created an infrastructure for no code machine learning (NML) platform for non-programming physicians to create NML model. We tested the platform by creating an NML model for classifying radiographs for the presence and absence of clavicle fractures.
    METHODS: Our IRB-approved retrospective study included 4135 clavicle radiographs from 2039 patients (mean age 52 ± 20 years, F:M 1022:1017) from 13 hospitals. Each patient had two-view clavicle radiographs with axial and anterior-posterior projections. The positive radiographs had either displaced or non-displaced clavicle fractures. We configured the NML platform to automatically retrieve the eligible exams using the series\' unique identification from the hospital virtual network archive via web access to DICOM Objects. The platform trained a model until the validation loss plateaus. Once the testing was complete, the platform provided the receiver operating characteristics curve and confusion matrix for estimating sensitivity, specificity, and accuracy.
    RESULTS: The NML platform successfully retrieved 3917 radiographs (3917/4135, 94.7 %) and parsed them for creating a ML classifier with 2151 radiographs in the training, 100 radiographs for validation, and 1666 radiographs in testing datasets (772 radiographs with clavicle fracture, 894 without clavicle fracture). The network identified clavicle fracture with 90 % sensitivity, 87 % specificity, and 88 % accuracy with AUC of 0.95 (confidence interval 0.94-0.96).
    CONCLUSIONS: A NML platform can help physicians create and test machine learning models from multicenter imaging datasets such as the one in our study for classifying radiographs based on the presence of clavicle fracture.
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