OBJECTIVE: The purpose of this study was to evaluate the mandibular growth and/or projection following maxillary incisor proclination, overbite correction, and maxillary dentoalveolar expansion without the use of any class II mechanics, in growing class II division 2 patients treated with clear aligners.
METHODS: Before and after treatment cone-beam computed tomographic (CBCT) generated lateral and posteroanterior cephalograms of thirty-two patients with skeletal class II division 2, 16 in the treatment group and 16 in the untreated group, were reviewed to evaluate treatment-related changes. Upper incisors were proclined and protruded, as well as upper arch expansion and overbite correction were performed as part of their regular treatment. Cephalometric analysis was performed to evaluate skeletal and dental changes. Unpaired statistical t-tests were performed to determine if significant skeletal class II correction was achieved in the treatment group.
RESULTS: In the treatment group, after treatment, the upper incisors became more proclined and protruded, and the inter-molar width increased while the overbite was reduced compared to the control group. An increase in skeletal mandibular growth and forward projection was also observed, thus contributing to an improvement of the sagittal skeletal relationship as evidenced by ANB and Wits values compared to the control group.
CONCLUSIONS: A combination of upper incisor proclination, correction of deep overbite, and maxillary dentoalveolar expansion using clear aligners appears to contribute to an improvement of the skeletal class II relationship in growing patients with class II division 2.
CONCLUSIONS: This study shows that unlocking the mandible by correcting a deep overbite, proclining upper incisors, and expanding the upper arch in growing class II division 2 patients can improve skeletal class II using clear aligners. How to cite this article: Mirzasoleiman P, El-Bialy T, Wiltshire WA, et al. Evaluation of Mandibular Projection in Class II Division 2 Subjects Following Orthodontic Treatment Using Clear Aligners. J Contemp Dent Pract 2024;25(4):295-302.

The case in this study had moderate hypodontia, with both lower lateral incisors and the lower-left second premolar missing. A Class II division 2 relationship with severe crowding in the upper arch and a traumatic deep bite over a skeletal I base complicated the occlusion.
The plan was to extract the upper first premolars to relieve upper arch crowding and the lower-left impacted second premolar to preserve the bilateral class I molar relationship. A class I occlusal relationship was achieved through space opening in the lower lateral incisors region and space closure in the upper and lower premolars regions.
The use of orthodontic screws for bite opening and anterior segment retraction, in conjunction with bi-metric slot size selection in bracket prescription, was effective in controlling incisor inclination and interincisal angle. The use of an implant fixture before beginning the finishing stage allowed for a reduction in total treatment time and facilitated the provision of the final prosthesis before debonding the case. As a result, the patient was able to receive a satisfactory occlusion on the day of debonding.
This case of moderate hypodontia was successfully resolved by combining space closure and space opening effectively. To solve the arch problems in such Class II division 2 cases with severe crowding, extractions were required. To complete the case, this was combined with intrusive and retractive mechanics. In hypodontia cases, implants are an excellent choice for both aesthetics and functional restoration.

BACKGROUND: The predictability of incisor movement achieved by clear aligners among Class II division 2 patients is poorly understood. The aim of this retrospective study was to determine the effectiveness of clear aligners in proclining and intruding upper incisors and its influencing factors.
METHODS: Eligible patients with Class II division 2 malocclusion were included. For clear aligner therapy, three types of incisor movements were designed: proclination, intrusion and labial movement. Pre-treatment and post-treatment dental models were superimposed. The differences between predicted and actual (DPA) tooth movement of incisors were analyzed. Univariate and multivariate linear regression were used to analyze the potential influencing factors.
RESULTS: A total of 51 patients and their 173 upper incisors were included. Actual incisor proclination and intrusion were less than predicted ones (both P < 0.001), while actual labial movement was greater than predicted one (P < 0.001). Predictability of incisor proclination and intrusion was 69.8% and 53.3%, respectively. Multivariate linear regression revealed that DPA of proclination was significantly positively associated with predicted proclination (B = 0.174, P < 0.001), ipsilateral premolar extraction (B = 2.773, P < 0.001) and ipsilateral canine proclination (B = 1.811, P < 0.05), while negatively associated with molar distalization (B = - 2.085, P < 0.05). The DPA of intrusion was significantly positively correlated with predicted intrusion (B = 0.556, P < 0.001) while negatively associated with labial mini-implants (B = - 1.466, P < 0.001). The DPA of labial movement was significantly positively associated with predicted labial movement (B = 0.481, P < 0.001), while negatively correlated with molar distalization (B = - 1.004, P < 0.001), labial mini-implants (B = - 0.738, P < 0.001) and age (B = - 0.486, P < 0.05).
CONCLUSIONS: For Class II division 2 patients, predicted incisor proclination (69.8%) and intrusion (53.3%) are partially achieved with clear aligner therapy. Excessive labial movement (0.7 mm) of incisors may be achieved. Incisor movement is influenced by predicted movement amount, premolar extraction, canine proclination, molar distalization, mini-implants and age.

Condylar displacement and remodelling are phenomena closely related to orthognathic surgery and critically involved in occlusal and skeletal stability. The aim of the present case report is to describe over time condylar displacement and surface remodelling after bilateral split sagittal osteotomy (BSSO) in an adult patient with severe class II skeletal malocclusion treated with ortho-surgical approach. A male of 21years comes to our observation. The extraoral examination shows a symmetrical square-shaped face, a convex profile, an acute nasolabial angle and a deep labiomental fold. Intraoral examination reveals a class II division 2 with a 2mm deviation of the mandibular midline to the left and the presence of a scissor bite of the bicuspids between quadrants II and III. The Spee curve and overbite are extremely accentuated (OV 14.3mm) as the overjet (11.1mm). Axiographic reconstructions of CBCT show a normal shape and position of both condyles. The cephalometric analysis shows a reduced lower facial height, a normal upper jaw position, a mandibular underdevelopment masked by a very developed symphysis and an extremely low divergence (FMA 11.2°). BSSO for mandibular setback was performed in the 13th month of orthodontic therapy. Original CBCT data before surgery (T0), at the end of treatment (T1), 2years postoperatively (T2) and 5years postoperatively (T3) were collected and reconstructed for 3-dimensional (3D) qualitative analyse. At the end of the surgical-orthodontic treatment (26months), good function and good aesthetics were achieved. The qualitative and comparative analysis of the superimpositions and the cuts made on the CBCT at T0, T1, T2, T3 showed a physiological remodelling and adaptation of the condyles.

Introduction The objective of this observational study is to compare the dental and skeletal changes that occur following the release of incisor locking in class II division 2 patients in the decelerating phase of the adolescent growth spurt. Materials and methods Lateral cephalograms of 17 subjects with skeletal class II and division 2 malocclusion, taken at the pre-treatment (T1) and post-leveling and alignment (T2) phases, were analyzed. All these patients were treated with non-extraction methods in the initial stage. A total of 25 skeletal and dental parameters, which included linear and angular measurements, were evaluated. Statistical analysis A paired t-test was used to compare the difference in the dimensional values between (T1) and (T2) points of the time period. The results were considered statistically significant at Bonferroni adjusted p<0.002. Results A statistically significant positional change was noted in the condylar position both in the vertical and sagittal directions, resulting in sagittal changes of the mandible in the forward direction. The deep bite was relieved by vertical changes in the dental structures in both the posterior and anterior segments. Growth changes in the vertical direction were also noted but not conclusive. Conclusions There was a definite horizontal shift of the mandible, improving maxillo-mandibular relations following the unlocking of the bite in class II division 2 patients. This shift is mostly attributed to the condylar repositioning in the forward and downward directions.

Class II malocclusions are one of the most commonly encountered problems in orthodontics. A class II division 2 type of malocclusions is one in which there is distocclusion of the molars along with retroclined central incisors. These occur but quite rarely in the practice and not many varieties of treatment modalities have been published in the recent literature. The use of protraction and retraction utility arch has been advocated in the following case along with fixed orthodontic treatment in a prepubertal male child to obtain stable results.
UNASSIGNED: Kannan S, Saravanan S, Arora N, et al. Treatment of Class II Division 2 Pattern malocclusion Using Protraction Utility Arch in a Prepubertal Patient: A Clinical Case Report. Int J Clin Pediatr Dent 2020;13(4):416-420.

The 3 Noffel signs, \"Ramal height\", \"Smiling chin\", and \"B-line space\", often present in class II division 2, are called \"danger signs\" for aesthetics, when they are strongly marked and absolutely need to be taken into account in the therapeutic strategy. The main objective was to assess whether the three measurements associated with Noffel signs (Gonion/Articulare distance, Cutaneous Pogonion/Na-B, and B-line space) were pathognomonic of class II division 2. The secondary objective was to determine whether there was a correlation between the severity of Noffel signs and the sagittal and/or vertical skeletal severity of class II division 2.
In this comparative, mono-centric study based on a retrospective cohort, lateral cephalograms of all the growing patients who were treated at the CSERD between 2012 and 2018 and had normodivergent and hypodivergent profiles, were analysed.
The logistic regression analysis showed that only \"Total chin\" and \"B-line space\" were significantly related to class II division 2 (P=0.00199; P=0.00778, respectively). The three signs were related to the severity of the hypodivergence, but not to the severity of skeletal class II.
Only \"Total chin\" and \"B-line space\" are pathognomonic of class II division 2. The correlation between the severity of Noffel\'s three signs and skeletal severity exists only in the vertical dimension.

This paper describes the orthodontic treatment of two cases that were successful in winning the British Orthodontic Society (BOS) Membership in Orthodonitcs (MOrth) cases prize in 2014. The first case describes the management of a 26-year-old female with a Class II division 2 incisor relationship on a Class III skeletal base with reduced vertical proportions. This was complicated by: an unerupted ectopic palatally displaced upper right permanent canine, an erupted palatally displaced upper left permanent canine, retained deciduous canines, generalised microdontia, an overall Bolton tooth size discrepancy, mild crowding in the upper arch, an increased overbite (complete to tooth tissue) and crossbites. Treatment involved a surgical exposure of the ectopic canine and the use of fixed pre-adjusted edgewise appliances over a period of 24 months. The second case describes the management of a 12-year-old female with a Class II division 2 incisor relationship on a Class 2 skeletal base with reduced vertical proportions. This was complicated by: an increased overjet and overbite (complete to soft tissue), mild upper and lower arch crowding and an increased naso-labial angle. Treatment involved an initial phase of modified Clark Twin Block and sectional fixed appliances followed by complete fixed pre-adjusted edgewise appliances over a period of 24 months.

OBJECTIVE: To identify and evaluate changes in the sagittal position of point B due to orthodontic treatment using CBCT.
METHODS: The subjects comprised 80 patients received fixed appliance. In this population, group 1 consisting of 40 patients with Class II division 2 malocclusion and group 2 consisting of 40 patients with minor crowding in the beginning of the treatment and required no or minimal maxillary anterior tooth movement. Treatment changes in incisor inclination, sagittal position of point B, SNB and movement of incisor root apex and incisal edge were calculated on pretreatment and post treatment on CBCT.
RESULTS: Assessment of local changes in point B revealed that the point had moved backward. No significant change was observed in the value of the sella-nasion-point B angle (SNB) in both the study and control groups. However, the changes of horizontal displacement after treatment in SNB between the two groups were found to be significant. There were no significant changes in the vertical and Z position of points B in both group.
CONCLUSIONS: The position of point B was affected by local bone remodeling during orthodontic treatment. These changes significantly affect the SNB angle.

This paper describes the clinical treatment of two cases treated by the recipient of the 2013 Membership in Orthodontics John Kay Williams Gold Medal of the Royal College of Surgeons of England and Glasgow. The first case describes the management of a 12-year-old male with a class II division 1 malocclusion complicated by Molar Incisal Hypominaralization, an increased overjet and severe upper arch crowding using fixed appliances with anchorage support from temporary anchorage devices. The second case involves the management of a class II division 2 malocclusion complicated by crowding of the upper and lower arches treated on an extraction basis using fixed appliances.