目标:产后抑郁症(PPD)影响10-15%的产后妇女,在有创伤史的妇女中风险增加。目的探讨贝都因人和犹太妇女不良生活事件与产后抑郁症状的关系。
方法:在2021年11月至2022年3月期间,在以色列南部地区的一家三级医院对单胎分娩的妇女进行了横断面研究。符合条件的女性填写了两份问卷,以确定儿童创伤(CT)和其他潜在创伤事件(PTE)的暴露情况。包括童年创伤问卷(CTQ),和终身事件清单调查表(LEC)。为了测量PPD的风险,我们使用了爱丁堡产后抑郁量表(EPDS)。CT之间的关联,PTE,并分析PPD风险,构建多变量逻辑回归模型以控制潜在的混杂因素.
结果:共包括201名妇女,120名贝都因人(59.7%)和81名犹太人(40.2%)。在整个研究人群中,CT和PTE均与PPD风险独立相关(校正OR=2.13,95%CI1.02-4.44,p=0.043,校正OR=3.42,95%,CI1.46-8.00,p=0.004)。而在贝都因妇女中,PTE与PPD风险独立相关(校正后OR=4.83,95%CI1.66-14.05,p=0.004),在犹太妇女中未发现显著关联.
结论:在贝都因人和犹太妇女中,CT和PTE均与PPD风险增加相关。只有PTE,而不是CT,在贝都因妇女中与PPD有关。了解PPD的危险因素,以及少数群体之间的差异,可以促进PPD的预防工作。
OBJECTIVE: Postpartum depression (PPD) affects 10-15% of postpartum women with increased risk among women with trauma history. The purpose of this study was to investigate the relationship between adverse life events and postpartum depressive symptoms among Bedouin and Jewish women.
METHODS: A cross-sectional study was performed in a tertiary hospital in the southern district of Israel on women with singleton deliveries between November 2021 and March 2022. Eligible women completed two questionnaires to determine exposure to childhood trauma (CT) and other potentially traumatic events (PTE), including the Childhood Trauma Questionnaire (CTQ), and Lifetime Events Checklist questionnaire (LEC). To measure risk for PPD we used the Edinburgh Postnatal Depression Scale (EPDS). The associations between CT, PTE, and risk for PPD were analyzed and multivariable logistic regression models were constructed to control for potential confounders.
RESULTS: A total of 201 women were included, 120 Bedouin (59.7%) and 81 Jewish (40.2%). In the entire study population, both CT and PTE were independently associated with risk for PPD (adjusted OR = 2.13, 95% CI 1.02-4.44, p = 0.043 and adjusted OR = 3.42, 95%, CI 1.46-8.00, p = 0.004, respectively). While among Bedouin women, PTE was independently associated with PPD risk (adjusted OR = 4.83, 95% CI 1.66-14.05, p = 0.004), no significant association was found among Jewish women.
CONCLUSIONS: Both CT and PTE were associated with increased PPD risk in Bedouin and Jewish women. Only PTE, and not CT, was associated with PPD among Bedouin women. Understanding risk factors for PPD, and differences among minority groups, could promote prevention efforts for PPD.