Djulis(ChenopodiumformosanumKoidz),富含营养物质,含有多种生物活性成分,如多酚和生物碱。新化合物具有广阔的应用前景,包括食品添加剂,健康产品,毒品,等。这项研究的目的是从Djulis中发现新化合物。发现24个化合物包括7个酚类,11类黄酮,4植物生物碱,2固醇。其中,TCI-CF-22-S(3,6-二羟基-2-氧代-1,2,3,4-四氢喹啉-3-羧酸甲酯),TCI-CF-23-S(6-羟基-2-氧代-1,2,3,4-四氢喹啉-3-甲酸甲酯),TCI-CF-24-S(山奈酚-3-O-b-D-阿呋喃基-(1→2)-a-L-阿拉伯吡喃糖苷)首次从djulis来源中分离出,化合物的结构由1D指定,2DNMR光谱。TCI-CF-01(咖啡酸),TCI-CF-02(20-羟基蜕皮激素),TCI-CF-03(Japonicone),TCI-CF-04(3,4-二羟基苯基醋酸盐),TCI-CF-05(槲皮素-3-O-芦丁苷-7-O-鼠李糖苷),TCI-CF-06(鸟苷),TCI-CF-07(腺嘌呤),TCI-CF-08(香豆酸)增加胶原蛋白的产生,和TCI-CF-03(日本硅胶),TCI-CF-04(3,4-二羟基苯基醋酸盐),TCI-CF-06(鸟苷),TCI-CF-17(芦丁),TCI-CF-20(原儿茶酸)降低晚期糖基化终产物(AGEs)。此外,TCI-CF-22-S(6-羟基-2-氧代-1,2,3,4-四氢喹啉-3-甲酸甲酯),TCI-CF-23-S(3,6-二羟基-2-氧代-1,2,3,4-四氢喹啉-3-羧酸甲酯)抑制脂肪油滴的形成。Djulis有24种化合物,可能有各种应用,包括增加胶原蛋白的产生和减少糖基化终产物和脂肪油滴。
Djulis (
Chenopodium formosanum Koidz), is rich in nutrients and contains various bioactive components such as polyphenols and alkaloids. The new compound has a broad application prospect, including food additives, health products, drugs, etc. The purpose of this study was to find out new compounds from Djulis. It was found that 24 compounds including 7 phenols, 11 flavonoids, 4 plant alkaloids, 2 sterols. Among those, TCI-CF-22-S (Methyl 3,6-dihydroxy-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate), TCI-CF-23-S (Methyl 6-hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate), TCI-CF-24-S (Kaempferol-3-O-b-D-apifuranosyl-(1→2)-a-L-arabinopyranoside) were isolated from djulis sources for the first time, and the structures of compounds were assigned by 1D, 2D NMR spectroscopy. TCI-CF-01(Caffeic acid), TCI-CF-02 (20-Hydroxyecdysone), TCI-CF-03 (Japonicone), TCI-CF-04 (3,4-Dihydroxyphenylacetiate), TCI-CF-05 (Quercetin-3-O-rutinoside-7-O-rhamnopyranoside), TCI-CF-06 (Guanosine), TCI-CF-07(Adenine), TCI-CF-08 (Coumaric acid) increased collagen production, and TCI-CF-03 (Japonicone), TCI-CF-04 (3,4-Dihydroxyphenylacetiate), TCI-CF-06 (Guanosine), TCI-CF-17 (Rutin), TCI-CF-20 (Protocatechuic acid) decreased advanced glycation end products (AGEs). In addition, TCI-CF-22-S (Methyl 6-hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate), TCI-CF-23-S (Methyl 3,6-dihydroxy-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate) inhibited the formation of fatty oil droplets. Djulis has 24 compounds that may have various applications, including increasing collagen production and reducing advanced glycation end products and fatty oil droplets.