2020年,SARS-COV-2病(COVID-19)给健康带来了巨大挑战,经济,和政治制度,到今年年底,随着旨在结束这场大流行的COVID-19疫苗的发布,人们产生了希望。然而,COVID-19疫苗接种计划引发了一些关于安全问题的担忧和持续的辩论。这里,我们介绍了三例严重不良事件的患者,脑病,疫苗诱导的血栓性血小板减少症,白细胞碎裂性血管炎,在接受ChAdOx1nCoV-19疫苗后。因此,调查和报告疫苗接种后不良反应的发生至关重要,特别严重的,因为它有助于不断增长的研究,并帮助临床医生更好地诊断和管理它们。
In 2020, the SARS-COV-2 disease (COVID-19) imposed huge challenges on the health, economic, and political systems, and by the end of the year, hope had been born with the release of COVID-19 vaccines aimed at bringing the pandemic to an end. However, the COVID-19 vaccination programs have sparked several concerns and ongoing debates over safety issues. Here, we presented three cases of patients with serious adverse events, encephalopathy, vaccine-induced thrombotic thrombocytopenia, and leukocytoclastic vasculitis, after receiving the ChAdOx1 nCoV-19 vaccine. Therefore, it is critical to investigate and report the occurrence of adverse reactions following vaccination, particularly serious ones, as it contributes to the growing body of research and assists clinicians in better diagnosing and managing them.