背景:这项研究的目的是确定在2020年期间,是否与COVID-19大流行相吻合,与前2年相比,儿童糖尿病的发病率有所增加。这也是为了找出封锁和在卫生系统中提供面对面护理的困难是否导致儿童在诊断时表现出更严重的症状。
方法:塔拉戈纳省的回顾性观察多中心研究,该研究收集了2020年15岁以下患者1型糖尿病的新诊断数据,并与2018年和2019年进行了比较。
结果:2020年1型糖尿病新诊断病例为37例,而2019年和2018年分别为23例和29例。发病年龄中位数为9岁,54%的男性。10至14岁儿童的新诊断有所增加,0-4岁儿童的范围减少。2020年,马格里布地区家庭患者组的发病率从2019年的每100,000人口/年52.2例(c/105p-y)上升到2020年的135.8例。与前一年相比,2020年显示酮症酸中毒在发病时显著减少。所有患者在入院期间均未被诊断为COVID-19。
结论:在与COVID-19大流行一致的2020年,儿科新诊断1型糖尿病的数量有所增加.与预期相反,发病时酮症酸中毒的比例降低并没有使临床表现恶化.这些数据表明,尽管不同医疗机构的出勤率在2020年大幅下降,但以虚拟咨询为代价,卫生系统和家庭能够早期发现疾病的症状。
BACKGROUND: The aim of this study is to determine whether during the year 2020, coinciding with the COVID-19 pandemic, there has been an increase in the incidence of diabetes mellitus in children compared to the previous 2 years. It is also to find out if lockdowns and the difficulty providing face-to-face care in the health system have led to children showing more severe symptoms at the time of diagnosis.
METHODS: Retrospective observational multicenter study of the province of Tarragona where data is collected from new diagnoses of type 1 diabetes mellitus in patients under the age of 15 during the year 2020 and compared with years 2018 and 2019.
RESULTS: The number of new diagnoses of type 1 diabetes during 2020 was 37 cases compared to 2019 and 2018 which was 23 and 29 respectively. The median age at onset was 9 years, 54% males. There was an increase in new diagnoses in the range of 10 to14-year-olds, with a decrease in the range of 0-4 year-olds. In 2020, the incidence in the group of patients with families from the Maghreb area rose from 52.2 cases per 100,000 population/year (c/105 p-y) in 2019 to 135.8 in 2020. Compared to the previous year, 2020 showed a significant decrease of ketoacidosis at the onset. None of the patients was diagnosed with COVID-19 during admission.
CONCLUSIONS: During the year 2020 concurring with the COVID-19 pandemic, there was an increase in the number of new diagnoses of type 1 diabetes mellitus in pediatrics. Contrary to expectations, the presentation did not worsen by decreasing the proportions of ketoacidosis at onset. This data would suggest that, although attendance in the different health facilities dropped drastically during the year 2020 at the expense of virtual consultations, health systems and families were able to detect the symptoms of the disease early.