Cervical deformity

颈椎畸形
  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    颈椎畸形患者的手术治疗对患者和医生都具有挑战性。为了成功的手术治疗,过程的掌握对于客观评估和分类畸形的程度很重要。最近,系统地理解,评估,有效治疗复杂颈椎畸形。正在开发各种参数来量化和客观评估颈椎畸形的程度,并引入分类方法,通过根据畸形程度进行分类来帮助建立治疗范围。然而,仅使用目前介绍的分类方法和相关知识对复杂畸形进行全面系统的了解并不容易。通过这次审查,我们旨在介绍各种分类方法及其优缺点来评估颈椎畸形,分析其含义,并为颈椎畸形患者的评估和分类提供基本的了解。这篇综述还旨在通过提出基于最近已知的分类系统的结构化治疗算法来帮助颈椎畸形治疗的决策过程,并为有效治疗奠定基础。
    Surgical treatment for patients with cervical spine deformities is challenging for both patients and doctors. For successful surgical treatment, mastery of processes is important to objectively evaluate and classify the degree of deformity. Recently, efforts have been increasing to systematically understand, evaluate, and effectively treat complex cervical spine deformities. Various parameters are being developed to quantify and objectively evaluate the degree of cervical spine deformity, and classification methods are being introduced to help establish the treatment scope by categorizing it according to the degree of deformity. However, a comprehensive and systematic understanding of complex deformities using only the currently introduced classification methods and related knowledge is not easy. Through this review, we aimed to introduce various classification methods and their pros and cons to evaluate cervical deformities, analyze their meaning, and provide a basic understanding of the evaluation and classification of patients with cervical spine deformities. This review also aimed to aid in the decision-making process for the treatment of cervical spine deformities by presenting a structured treatment algorithm based on recently known classification systems and lay the foundation for efficient treatment.
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  • 文章类型: Journal Article
    方法:系统评价。
    目的:评估颈椎前路椎间盘切除融合术(ACDF)和颈椎前路椎体切除融合术(ACCF)哪种颈椎畸形矫正技术能产生更好的临床效果,射线照相,和手术结果。
    方法:我们进行了一项荟萃分析,比较了涉及ACDF和ACCF的研究。包括患有原始或先前治疗过的颈椎畸形的成年患者。两名独立评审员将提取的数据分类为临床,射线照相,和手术结果,包括并发症。临床评估包括患者报告的结果;影像学评估检查C2-C7Cobb角,T1斜率,T1-CL,C2-7SVA,和移植物稳定性。手术措施包括手术时间,失血,住院,和并发症。
    结果:26项研究(25727例患者)符合纳入标准并被提取。其中,荟萃分析中纳入了14项具有低偏倚风险的研究(19077例患者)。ACDF和ACCF同样改善了JOA和NDI的临床结果,但ACDF在实现较低的VAS颈部评分方面明显更好。ACDF还更有利于改善宫颈前凸和最小化移植并发症的发生率。虽然大多数手术并发症的方法之间没有显着差异,ACDF有利于减少手术时间,术中失血,和住院时间。
    结论:虽然这两种技术都有益于颈椎畸形患者,当两种技术都可行时,ACDF可能优于VAS颈部评分,宫颈前凸,移植物并发症和某些围手术期结果。建议进一步研究以解决结果变异性并改进手术方法选择。
    METHODS: Systematic Review.
    OBJECTIVE: To evaluate which cervical deformity correction technique between anterior cervical discectomy and fusion (ACDF) and anterior cervical corpectomy and fusion (ACCF) produces better clinical, radiographic, and operative outcomes.
    METHODS: We conducted a meta-analysis comparing studies involving ACDF and ACCF. Adult patients with either original or previously treated cervical spine deformities were included. Two independent reviewers categorized extracted data into clinical, radiographic, and operative outcomes, including complications. Clinical assessments included patient-reported outcomes; radiographic evaluations examined C2-C7 Cobb angle, T1 slope, T1-CL, C2-7 SVA, and graft stability. Surgical measures included surgery duration, blood loss, hospital stay, and complications.
    RESULTS: 26 studies (25727 patients) met inclusion criteria and were extracted. Of these, 14 studies (19077 patients) with low risk of bias were included in meta-analysis. ACDF and ACCF similarly improve clinical outcomes in terms of JOA and NDI, but ACDF is significantly better at achieving lower VAS neck scores. ACDF is also more advantageous for improving cervical lordosis and minimizing the incidence of graft complications. While there is no significant difference between approaches for most surgical complications, ACDF is favorable for reducing operative time, intraoperative blood loss, and length of hospital stay.
    CONCLUSIONS: While both techniques benefit cervical deformity patients, when both techniques are feasible, ACDF may be superior with respect to VAS neck scores, cervical lordosis, graft complications and certain perioperative outcomes. Further studies are recommended to address outcome variability and refine surgical approach selection.
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  • 文章类型: Journal Article
    背景:远端交界性脊柱后凸(DJK)是外科医生进行颈椎畸形(CD)手术的一个值得关注的并发症。与未受影响的同龄人相比,维持此类并发症的患者可能表现出更差的恢复状况。方法:DJK定义为LIV和LIV-2之间后凸的变化>10°,指数角>10°。CD患者根据3M与DJK的发展情况进行分组没有DJK开发。均值比较测试和回归分析用于分析组间差异和相关关联。结果:共纳入113例患者(17DJK,96非DJK)。DJK患者术前矢状错位更多,并接受了更多的截骨术和联合入路。Postop,DJK患者出现更多吞咽困难(17.7%vs.4.2%;p=0.034)。在2年的随访中,DJK患者在cSVA中仍然更加不一致。DJK患者从3M到1Y表现出较差的患者报告结果,但当跟踪患者到2Y时,这些差异消失了;他们也表现出更差的NDI(65.3vs.35.3)和EQ5D(0.68vs.0.79)在1Y时得分(均p<0.05),但这些差异在2Y时已经消退。结论:尽管患者表现出相似的术前健康相关生活质量指标,早期发展DJK的患者在发展DJK后表现出更严重的术后颈部残疾.这些差异在两年的随访中得到了缓解,强调了许多DJK患者在CD手术后的长期但最终成功的过程。
    Background: Distal junctional kyphosis (DJK) is a concerning complication for surgeons performing cervical deformity (CD) surgery. Patients sustaining such complications may demonstrate worse recovery profiles compared to their unaffected peers. Methods: DJK was defined as a >10° change in kyphosis between LIV and LIV-2, and a >10° index angle. CD patients were grouped according to the development of DJK by 3M vs. no DJK development. Means comparison tests and regression analyses used to analyze differences between groups and arelevant associations. Results: A total of 113 patients were included (17 DJK, 96 non-DJK). DJK patients were more sagittally malaligned preop, and underwent more osteotomies and combined approaches. Postop, DJK patients experienced more dysphagia (17.7% vs. 4.2%; p = 0.034). DJK patients remained more malaligned in cSVA through the 2-year follow-up. DJK patients exhibited worse patient-reported outcomes from 3M to 1Y, but these differences subsided when following patients through to 2Y; they also exhibited worse NDI (65.3 vs. 35.3) and EQ5D (0.68 vs. 0.79) scores at 1Y (both p < 0.05), but these differences had subsided by 2Y. Conclusions: Despite patients exhibiting similar preoperative health-related quality of life metrics, patients who developed early DJK exhibited worse postoperative neck disability following the development of their DJK. These differences subsided by the 2-year follow-up, highlighting the prolonged but eventually successful course of many DJK patients after CD surgery.
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  • 文章类型: Journal Article
    背景/目标:由于它们的高频率,常见的风险因素,和类似的致病机制,肌肉骨骼疾病(MSD)更有可能与其他慢性疾病一起发生,使它们成为多发病的“成分紊乱”。我们的目标是评估多症的患病率,并确定多症状态中最常见的诊断簇。主要假设是多发病率的最常见簇是MSD。方法:本研究采用了基于人群的2019年欧洲健康访谈调查(EHIS)的数据。多发病被定义为17种慢性非传染性疾病的诊断≥2,并定义集群,采用层次聚类分析(HCA)的统计方法。结果:在13,178名受访者中,4398人中存在多发病率(33.4%)。HCA方法产生了六个代表最常见诊断的多患病簇。主要多患病率群,这在两种性别中都很普遍,年龄组,人均收入,和统计区域,包括三个诊断:(1)下脊柱畸形或其他慢性背部问题(背痛),(2)颈椎畸形或其他颈椎慢性问题,(3)骨关节炎。结论:鉴于肌肉骨骼疾病对多发性疾病的影响,必须采取适当措施,帮助病人减轻身体上的不适和痛苦。公共卫生信息,programs,应该利用运动来促进健康的生活方式。政策制定者应通过鼓励增加体育锻炼和健康饮食来优先预防MSD,以及专注于提高功能能力。
    Background/Objectives: Due to their high frequency, common risk factors, and similar pathogenic mechanisms, musculoskeletal disorders (MSDs) are more likely to occur with other chronic illnesses, making them a \"component disorder\" of multimorbidity. Our objective was to assess the prevalence of multimorbidity and to identify the most common clusters of diagnosis within multimorbidity states, with the primary hypothesis that the most common clusters of multimorbidity are MSDs. Methods: The current study employed data from a population-based 2019 European Health Interview Survey (EHIS). Multimorbidity was defined as a ≥2 diagnosis from the list of 17 chronic non-communicable diseases, and to define clusters, the statistical method of hierarchical cluster analysis (HCA) was performed. Results: Out of 13,178 respondents, multimorbidity was present among 4398 (33.4%). The HCA method yielded six multimorbidity clusters representing the most common diagnoses. The primary multimorbidity cluster, which was prevalent among both genders, age groups, incomes per capita, and statistical regions, consisted of three diagnoses: (1) lower spine deformity or other chronic back problem (back pain), (2) cervical deformity or other chronic problem with the cervical spine, and (3) osteoarthritis. Conclusions: Given the influence of musculoskeletal disorders on multimorbidity, it is imperative to implement appropriate measures to assist patients in relieving the physical discomfort and pain they endure. Public health information, programs, and campaigns should be utilized to promote a healthy lifestyle. Policymakers should prioritize the prevention of MSDs by encouraging increased physical activity and a healthy diet, as well as focusing on improving functional abilities.
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  • 文章类型: Case Reports
    由于患病率低(0%-4%),上颌第一磨牙中的第二远颊管经常被错过。本文在一个案例中报告了这种变化。有希望的结果一直持续到现在(2年随访)。
    The second distobuccal canal in the maxillary first molar is often missed because of the low prevalence rate (0%-4%). The article reports this kind of variation in one case. Promising outcomes have continued up to the present (2-year follow-up).
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  • 文章类型: Case Reports
    椎动脉损伤(VAI)是颈椎后路融合手术的已知潜在并发症。术前成像用于在计划和执行手术期间确定双侧椎动脉的通畅性。此病例说明了分阶段的前/后颈椎重建的示例,其中医源性VAI与术前成像中未识别的对侧特发性椎动脉夹层联合导致基底动脉顺行血流缺失。
    一名61岁女性患者,接受计划分期的颈椎前路减压C4-T1+颈椎后路融合术C2-T4治疗退行性颈椎病。第二阶段后路融合,在钻孔过程中发生医源性VAI,以放置右C2pars螺钉。术后血管造影时,除了已知的右VAI,有一个新的左椎动脉夹层发生在前阶段期间/之后。基底动脉仅从右颈内动脉穿过右后交通动脉以逆行方式填充。使用伸缩式分流支架治疗左椎动脉夹层,以恢复至基底动脉的流量,并使用盘绕治疗右VAI。
    外科医生应该意识到这种可能性,虽然罕见,如果在颈椎手术期间发生了明显的畸形矫正或对齐改变,则总是有可能对未受伤的动脉造成隐匿性伤害。与神经介入同事密切合作可以快速评估,如有必要,通过这些救命技术恢复大脑的血液流动。
    UNASSIGNED: Vertebral artery injury (VAI) is a known potential complication of posterior cervical fusion surgery. Pre-operative imaging is used to determine the patency of bilateral vertebral arteries during the planning and execution of surgery. This case illustrates an example of a staged anterior/posterior cervical reconstruction in which an iatrogenic VAI combined with a contralateral idiopathic vertebral artery dissection not identified on pre-operative imaging resulted in absent basilar artery anterograde flow.
    UNASSIGNED: A 61-year-old female underwent planned staged anterior cervical decompression C4-T1 with posterior cervical fusion C2-T4 for the treatment of degenerative cervical myeloradiculopathy. During the second stage posterior fusion, iatrogenic VAI occurred during drilling for placement of the right C2 pars screw. Upon post-operative angiography, in addition to the known right VAI, there was a new left vertebral artery dissection that occurred during/after the anterior stage. The basilar artery was only filled in retrograde fashion from the right internal carotid artery across the right posterior communicating artery. The left vertebral artery dissection was treated with telescoping flow diverting stents to restore flow to the basilar artery and the right VAI was treated with coiling.
    UNASSIGNED: Surgeons should be aware of the possibility, while rare, that an occult injury to the non-injured artery is always a possibility if significant deformity correction or alignment change has occurred during cervical spine surgery. Working closely with neurointerventional colleagues can be invaluable to quickly assess and if necessary, restore blood flow to the brain through these life saving techniques.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    背景:先前的研究表明,成年宫颈畸形患者的死亡风险可能会增加,同时伴有虚弱或生理状态减弱。然而,这些研究往往受到随访时间的限制,需要进行更长期的研究来更好地评估ACD患者的时间变化和相关的死亡风险.
    目的:评估合并症和生理负担减少的患者在接受成人宫颈畸形手术后,死亡风险是否会降低。
    方法:回顾性回顾患者样本:两百九十例ACD患者结局指标:发病率和死亡率数据。
    方法:包括术前(BL)和10年(10Y)数据的≥18岁ACD患者。患者被分层为过期和活着,以及在5Y之前或5Y和10Y之间按到期时间分组。通过均值比较分析评估组差异。Backstep逻辑回归确定了死亡率预测因子。Kaplan-Meier分析评估了过期患者的生存率。Logrank分析确定生存分布组的差异结果:共纳入66例患者(60.97±10.19年,48%为女性,28.03±7.28kg/m2)。在10Y内,12(ACD队列的18.2%)过期。在基线,患者的年龄相当,性别,BMI,和CCI总计平均(所有p>0.05)。此外,患者的BLHRQL具有可比性(均p>.05)。然而,在5Y和10Y之间过期的患者在2Y时表现出比较早过期的患者更高的BLEQ5D和mJOA评分(p<.021).此外,在BL时未出现CCI标记的患者在5Y-10Y随访窗前存活的可能性显著增加.手术,存活到5Y的患者之间观察到的唯一差异是进行截骨术,那些不需要它的人的生存期更长(p=0.003)。Logistic回归显示5Y前死亡的独立预测因子是BMI增加,增加了脆弱,和增加的水平融合(模型p<.001)。KM分析发现,Passias等人。脆弱,不虚弱患者的平均生存时间为170.56周,与虚弱患者的158.00相比(p=.949)。
    结论:我们的研究表明,颈椎畸形手术后的长期生存可以通过基线手术因素来预测。通过优化BMI,脆弱状态,并在适当时最小化融合长度,外科医生可能能够进一步协助ACD患者提高术后生存能力。
    BACKGROUND: Previous studies have demonstrated that adult cervical deformity patients may be at increased risk of death in conjunction with increased frailty or a weakened physiologic state. However, such studies have often been limited by follow-up duration, and longer-term studies are needed to better assess temporal changes in ACD patients and associated mortality risk.
    OBJECTIVE: To assess if patients with decreased comorbidities and physiologic burden will be at lessened risk of death for a greater length of time after undergoing adult cervical deformity surgery.
    METHODS: Retrospective review.
    METHODS: Two hundred ninety ACD patients.
    METHODS: Morbidity and mortality data.
    METHODS: Operative ACD patients ≥18 years with pre-(BL) and 10-year (10Y) data were included. Patients were stratified as expired versus living, as well as temporally grouped by Expiration prior to 5Y or between 5Y and 10Y. Group differences were assessed via means comparison analysis. Backstep logistic regression identified mortality predictors. Kaplan-Meier analysis assessed survivorship of expired patients. Log rank analysis determined differences in survival distribution groups.
    RESULTS: Sixty-six total patients were included (60.97±10.19 years, 48% female, 28.03±7.28 kg/m2). Within 10Y, 12 (18.2% of ACD cohort) expired. At baseline, patients were comparable in age, gender, BMI, and CCI total on average (all p>.05). Furthermore, patients were comparable in BL HRQLs (all p>.05). However, patients who expired between 5Y and 10Y demonstrated higher BL EQ5D and mJOA scores than their earlier expired counterparts at 2Y (p<.021). Furthermore, patients who presented with no CCI markers at BL were significantly more likely to survive until the 5Y-10Y follow-up window. Surgically, the only differences observed between patients who survived until 5Y was in undergoing osteotomy, with longer survival seen in those who did not require it (p=.003). Logistic regression revealed independent predictors of death prior to 5Y to be increased BMI, increased frailty, and increased levels fused (model p<.001). KM analysis found that by Passias et al frailty, not frail patients had mean survival time of 170.56 weeks, versus 158.00 in frail patients (p=.949).
    CONCLUSIONS: Our study demonstrates that long-term survival after cervical deformity surgery may be predicted by baseline surgical factors. By optimizing BMI, frailty status, and minimizing fusion length when appropriate, surgeons may be able to further assist ACD patients in increasing their survivability postoperatively.
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  • 文章类型: Journal Article
    术中神经监测(IONM)已成为颈椎手术中必不可少的手术辅助手段,可最大程度地减少手术并发症。了解IONM的历史发展,使用适应症,相关的陷阱,和最近的发展将使外科医生更好地利用这一重要技术。虽然IONM在颈椎畸形的手术中显示出巨大的希望,硬膜内肿瘤,或者脊髓病,在所有中度病理的颈椎病例中常规使用仍存在争议.需要解决的陷阱包括人为错误,缺乏有效的沟通,可变报警警告标准,和非标准化的检查表协议。随着与IONM技术相关的技术变得更加强大,IONM成为更新患者安全协议的关键解决方案。
    Intraoperative neuromonitoring (IONM) has become an indispensable surgical adjunct in cervical spine procedures to minimize surgical complications. Understanding the historical development of IONM, indications for use, associated pitfalls, and recent developments will allow the surgeon to better utilize this important technology. While IONM has shown great promise in procedures for cervical deformity, intradural tumors, or myelopathy, routine use in all cervical spine cases with moderate pathology remains controversial. Pitfalls that need to be addressed include human error, a lack of efficient communication, variable alarm warning criteria, and a non-standardized checklist protocol. As the techniques associated with IONM technology become more robust moving forward, IONM emerges as a crucial solution to updating patient safety protocols.
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