■中央牙源性纤维瘤(COF)是一种罕见的,良性,生长缓慢的骨内牙源性肿瘤,占所有牙源性肿瘤的0.1%。它经常与其他实体混淆,如角化囊肿,成釉细胞瘤,和牙源性粘液瘤.完全摘除后进行刮宫是COF的治疗选择,以确保尽可能低的复发机会。
■我们报告了一例年轻的高加索女性患有COF的病例,尽管反复进行放射学检查,但该病例数年未被诊断。最后,手术切除了一个巨大的肿瘤,并刮除了伤口。该标本在组织学上被证实为COF。患者仍在定期随访中,到目前为止,还没有复发的临床或放射学迹象。
■这种罕见的COF病例,记录了20年的时间,帮助我们描述了这个肿瘤的特征。它还证实,适当的手术治疗可以导致健康个体令人印象深刻的骨骼再生,从之前获得的放射学发现可以明显看出,during,在我们病人的COF摘除后。我们的发现还证实了这样的观点,即无论其最终大小如何,COF都具有良好的预后。
■早期诊断是成功治疗COF的关键。以前没有报道过COF大小缓慢但稳定的增加,没有伴随症状。据我们所知,这是唯一有记录的连续放射学观察超过20年的COF病例.
UNASSIGNED: Central odontogenic fibroma (COF) is a rare, benign, slow-growing intraosseous odontogenic tumor, and accounts for 0.1% of all odontogenic tumors. It is often confused with other entities, such as keratocysts, ameloblastomas, and odontogenic myxomas. Complete enucleation followed by curettage is the treatment of choice for COF to ensure the lowest possible chance of recurrence.
UNASSIGNED: We report the case of a young Caucasian woman with COF that went undiagnosed for several years despite repeated radiologic examinations. Finally, a massive tumor was surgically removed and the wound was curetted. The specimen was histologically confirmed to be a COF. The patient remains under regular follow-up, and thus far there have been no clinical or radiologic signs of recurrence.
UNASSIGNED: This rare case of COF, which was documented over a period of 20 years, has helped us to describe the features of this tumor. It also confirms that adequate surgical treatment can lead to impressive bone regeneration in healthy individuals, as evident from the radiologic findings acquired before, during, and after enucleation of the COF in our patient. Our findings also confirm the view that COF has a favorable prognosis regardless of its final size.
UNASSIGNED: Early diagnosis is key to successful treatment of COF. The slow but steady increase in the size of a COF with no accompanying symptoms has not been reported previously. To our knowledge, this is the only documented case of a COF that has been under continuous radiologic observation for over 20 years.