Cauda Equina Syndrome

马尾综合征
  • 文章类型: Case Reports
    大多数创伤后脊髓空洞发生在颈脊髓或胸脊髓,它们会导致脊髓病变。这里,一名40岁患者在L2椎体“挤压”骨折10年后出现脊髓空洞累及延髓圆锥,导致左腿单瘫。
    L2椎体“挤压”骨折十年后,一名40岁男性出现新的左小腿轻瘫。磁共振成像显示T12-L1syrinx与位于T11和T12水平之间的syrinx上方伴随的高强度区域相关。放置注射器蛛网膜下腔(SS)分流术后一个月,syrinx和高强度区域迅速消失,左远端运动无力解决。
    L2“挤压”骨折十年后,一名40岁男性患者出现新发马尾综合征,继发于创伤后T12-L1脊髓空洞症,导致脊髓圆锥扩张.
    UNASSIGNED: Most posttraumatic syringomyelias occur in the cervical or thoracic spinal cord, where they contribute to myelopathic deficits. Here, a 40-year-old patient presented with the left leg monoparesis due to syringomyelia involving the conus medullaris 10 years after an L2 vertebral \"crush\" fracture.
    UNASSIGNED: Ten years following an L2 vertebral \"crush\" fracture, a 40-year-old male presented with the new onset of left lower leg paresis. The magnetic resonance imaging showed a T12-L1 syrinx associated with accompanying high-intensity areas above the syrinx located between the T11 and T12 levels. One month after placing a syringosubarachnoid (SS) shunt, both the syrinx and high-intensity area rapidly disappeared, and the left distal motor weakness resolved.
    UNASSIGNED: Ten years following an L2 \"crush\" fracture, a 40-year-old male presented with the new onset of a cauda equina syndrome secondary to a posttraumatic T12-L1 syringomyelia causing expansion of the conus medullaris.
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  • 文章类型: Journal Article
    怀孕期间的马尾是一种罕见的实体,有关最佳治疗的数据在相关文献中非常稀缺。鉴于目前有关该主题的证据很少,本研究对现有有关孕妇马尾综合征(CES)管理的文献进行了系统的回顾和分析。在多个数据库中进行了全面搜索,产生26篇符合纳入标准的IV级同行评审文章。这些研究共包括30名患有CES的孕妇,平均年龄31.2岁,平均胎龄26周。在73%的病例中,椎间盘突出是主要原因。关于手术干预,70%的病例使用了俯卧位,73%接受全身麻醉。值得注意的是,与妊娠早期相比,妊娠晚期脊柱手术的完全恢复率更高。与开放方法相比,微创脊柱手术在完全恢复和减少持续术后症状的风险方面表现出优异的效果。此外,与脊柱手术前或脊柱手术后阴道分娩的剖腹产患者相比,脊柱手术后接受剖腹产(CS)的患者报告的症状缓解率较高,症状持续率较低.尽管有这些研究发现,总体证据基础仍然有限,排除明确的结论。因此,该研究强调了多学科团队讨论对于为接受CES治疗的孕妇制定最佳治疗策略的重要性.这凸显了进一步研究的迫切需要,以扩大知识库并改进可用于管理怀孕人群CES的指导。
    Cauda equina during pregnancy represents a rare entity, with data regarding optimal treatment being very scarce in the pertinent literature. Given the scarcity of current evidence on the topic, this study conducts a systematic review and analysis of existing literature concerning cauda equina syndrome (CES) management in pregnant women. A comprehensive search was performed across multiple databases, yielding 26 level IV peer-reviewed articles that met the inclusion criteria. These studies collectively encompassed 30 pregnant patients with CES, with a mean age of 31.2 years and an average gestational age of 26 weeks. Disc herniation emerged as the primary cause in 73% of cases. Regarding surgical interventions, the prone position was utilised in 70% of cases, with 73% receiving general anaesthesia. Notably, third-trimester spinal surgeries exhibited a higher complete recovery rate compared to earlier trimesters. Minimally invasive spinal surgery demonstrated superior outcomes in terms of complete recovery and reduced risk of persistent post-operative symptoms when compared to open approaches. Moreover, patients undergoing caesarean section (CS) after spinal surgery reported higher rates of symptom resolution and lower symptom persistence compared to those with CS before spinal surgery or vaginal delivery post-spinal surgery. Despite these study\'s findings, the overall evidence base remains limited, precluding definitive conclusions. Consequently, the study underscores the importance of multidisciplinary team discussions to formulate optimal treatment strategies for pregnant individuals presenting with CES. This highlights a critical need for further research to expand the knowledge base and improve the guidance available for managing CES in pregnant populations.
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  • 文章类型: Case Reports
    Elsberg综合征是一种假定的传染性腰骶神经根炎,伴有或不伴有腰脊髓炎,这通常归因于单纯疱疹病毒2型(HSV-2)。
    一名58岁男子下肢麻醉,共济失调步态,神经根炎的放射学证据,和脑脊液白蛋白细胞分离。CSF的聚合酶链反应测试证实了HSV-2感染。
    在Elsberg综合征的范围内报道了各种介绍,可能有不同的疾病机制。皮疹消退后神经系统症状的延迟发作和细胞增多的缺乏增加了某些符合Elsberg综合征标准的患者感染后免疫介导的神经病变的可能性。我们建议在急性神经病和蛋白细胞分离的患者中进行疱疹病毒PCR检测的阈值较低。特别是在早期骶骨受累的病例中。
    UNASSIGNED: Elsberg Syndrome is a presumed infectious lumbosacral radiculitis, with or without accompanying lumbar myelitis, that is often attributed to herpes simplex virus type 2 (HSV-2).
    UNASSIGNED: A 58-year-old man presented with lower extremity anesthesia, ataxic gait, radiological evidence of radiculitis, and CSF albuminocytologic dissociation. Polymerase chain reaction testing of CSF confirmed HSV-2 infection.
    UNASSIGNED: A variety of presentations are reported within the scope of Elsberg Syndrome, potentially with distinct disease mechanisms. Delayed onset of neurological symptoms after resolution of rash and absence of pleocytosis raises the possibility that some patients meeting criteria for Elsberg Syndrome have a post-infectious immune-mediated neuropathy. We advise a lower threshold for PCR testing of herpes viruses in patients with acute neuropathy and albuminocytologic dissociation, particularly in cases with early sacral involvement.
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  • 文章类型: Case Reports
    背景技术除了稀有性的可移动脊柱神经鞘瘤,这些肿瘤与椎间盘突出的共存也很少。此外,马尾综合征(CES),作为椎管内神经鞘瘤的表现很少报道。这里描述的是同时出现腰椎间盘突出和活动性脊髓神经鞘瘤的病例,表现为CES的间歇性症状。病例报告一名62岁男子出现严重但间歇性的腿部疼痛2周,后来发展为下肢无力和排尿困难。磁共振成像显示脊柱内肿瘤在间隔6小时的扫描中相对于L1-2椎间盘凸起移动,与相关的症状自发消退。肿瘤被发现是一种可移动的脊髓神经鞘瘤,起源于神经根.使用标准的显微解剖技术通过保留棘突的单侧入路切除肿瘤,完整的L1椎板切除术。术中超声的使用促进了肿瘤的准确定位。术后,病人不再有症状。结论本报告提出了一个常见的脊柱病理学的组合,椎间盘突出,伴随着一种罕见的情况,移动脊髓神经鞘瘤,其罕见的临床表现,如CES可能导致不可逆的神经功能缺损。外科医生在治疗患者时需要对潜在的非典型情况保持警惕。关于肿瘤移动性的手术治疗挑战,比如准确的定位,应使用术中成像来避免错误级别的手术。为了减轻不可逆的神经系统并发症,患者应获得全面的信息,以了解CES的警报迹象。
    BACKGROUND Aside from the rarity of mobile spinal schwannomas, the coexistence of these tumors with herniated intervertebral disc is also scarce. Furthermore, cauda equina syndrome (CES), as a manifestation of intraspinal schwannomas has been reported rarely. Described here is a case of simultaneous lumbar disc bulge and mobile spinal schwannoma presented with intermittent symptoms of CES. CASE REPORT A 62-year-old man presented with severe but intermittent leg pain for 2 weeks, which later progressed to an episode of lower extremity weakness and difficulty in urination. Magnetic resonance imaging revealed an intraspinal tumor that moved in position relative to the L1-2 disc bulge on scans 6 h apart, with associated spontaneous regression in symptoms. The tumor was found to be a mobile spinal schwannoma, originated from a nerve root. A standard microdissection technique was used to remove the tumor through a spinous process-sparing unilateral approach, with complete laminectomy of L1. Use of intraoperative ultrasound facilitated the accurate tumor localization. Postoperatively, the patient no longer had symptoms. CONCLUSIONS This report presents a combination of a common spinal pathology, intervertebral disc herniation, alongside a rare condition, mobile spinal schwannoma, whose uncommon clinical manifestations, such as CES can cause irreversible neurological deficits. Surgeons need to remain vigilant of potential atypical scenarios when treating patients. Surgical treatment challenges regarding the mobility of tumors, such as accurate localization, should be addressed using intraoperative imaging to avoid wrong-level surgery. To mitigate the irreversible neurological complications, patients should receive comprehensive information for alarming signs of CES.
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  • 文章类型: Journal Article
    目标:Mebos,一种传统的南非甜点,制浆,加糖的杏子,富含纤维和维生素,但也含有水杨酸,黄酮类化合物,和柠檬酸。我们报告了一例健康患者的术后手术部位出血病例,该患者在择期脊柱手术前每天消耗约2公斤的mebos。
    方法:讨论了一名先前健康的54岁男性腰椎管狭窄继发马尾神经综合征患者的临床过程,该患者接受了手术干预,随后在手术部位出血。通过生化分析调查了原因,应用血栓弹性测定法(ROTEM®)和质谱和吸收光谱法来评估类黄酮,柠檬酸,和水杨酸含量。
    结果:ROTEM®显示异常凝血曲线,凝块形成时间增加,提示固有凝血障碍。质谱和吸收光谱法显示,墨鱼中的总黄酮含量很高,柠檬酸浓度也很高。水杨酸处于仪器的检测限。
    结论:结果强调了类黄酮和柠檬酸的作用,因此解释了该患者的异常凝血特征。在择期手术之前抑制凝血是已知的禁忌症,并且在脊柱手术中可能会带来很大的风险。在本报告中,我们证明了在择期脊柱手术前几天消耗的美博司体内,凝血抑制与过量的类黄酮含量和柠檬酸浓度之间存在关联.
    OBJECTIVE: Mebos, a traditional South Africa confection consisting of dried, pulped, and sugared apricots, is rich in fibre and vitamins, but also contains salicylic acid, flavonoids, and citric acid. We report a case of postoperative surgical site bleeding in a healthy patient who consumed approximately 2 kg of mebos per day prior to his elective spinal surgery.
    METHODS: The clinical course of a previously healthy 54-year-old male patient with cauda equina syndrome secondary to lumbar spinal stenosis who underwent surgical intervention with subsequent bleeding into the surgical site is discussed. The cause was investigated through biochemical analysis, thromboelastometry (ROTEM®) and mass and absorption spectrometry were applied to assess flavonoid, citric acid, and salicylic acid content.
    RESULTS: ROTEM® revealed an abnormal clotting profile with an increased clot forming time, suggesting intrinsic coagulopathy. Mass and absorption spectrometry revealed a high total flavonoid content as well as citric acid concentration in the mebos. Salicylic acid was at detection limits of the instrument.
    CONCLUSIONS: Results highlighted the effect of flavonoids and citric acid and therefore explain the abnormal clotting profile in this patient. Inhibition of coagulation prior to elective surgery is a known contraindication and may pose great risks in spinal surgery. In the present report, we demonstrated an association between inhibition of coagulation and an excess of the flavonoids content and citric acid concentration in mebos consumed in the days prior to elective spinal surgery.
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  • 文章类型: Journal Article
    背景:虽然是罕见的脊髓急症,马尾综合征(CES)可以导致显著的身体,情感,和心理后遗症。引入CES途径可增强诊断,但可能会增加放射学和骨科工作量。为了解决这个问题,英国一家NHS医院引入了一种新的CES途径。利用标准主导的途径,患者直接从社区/初级保健转诊,通过急诊室,做紧急核磁共振扫描.
    目的:比较通过原始和重新设计的社区和初级保健CES途径转诊的患者的结局。
    方法:对通过任一途径调查疑似CES的所有急诊MRI扫描进行回顾性服务评估。
    方法:分析了两个3个月的时间段;重新设计途径的实施前(原始)和实施后;在两个12个月的时间段内回顾了手术时间。
    结果:实施重新设计的途径后,MRI扫描利用率提高:原始n=50,重新设计n=128,放射学工作量增加。然而,重新设计的途径导致MRI时间从3h:01m减少到1h:02m;ED4h:55m减少到3h:24m;手术时间减少18h:05m减少到13h:38m;在评估期间,非小时扫描从10例减少到2例;随叫随到的骨科介入减少38%。
    结论:实施该新路径后,所有定时结局均得到改善。这表明加快MRI扫描可以导致实质性的下游益处;尽管同时增加MRI扫描利用率。该途径与英格兰新的国家CES途径下可疑CES的应急管理相一致。
    Although a rare spinal emergency, cauda equina syndrome (CES) can result in significant physical, emotional, and psychological sequalae. Introducing a CES pathway enhances diagnosis but may increase Radiology and Orthopaedic workload. To address this, one NHS hospital in England introduced a novel CES pathway. Utilising a criteria-led pathway, patients were referred directly from community/primary care, via the Emergency Department, for an emergency MRI scan.
    To compare the outcomes of patients referred via an original and redesigned Community and Primary Care CES pathway.
    A retrospective service evaluation was undertaken of all emergency MRI scans investigating suspected CES via either pathway.
    Two 3-month time periods were analysed; pre-(original) and post-implementation of the redesigned pathway; time to surgery was reviewed over two 12-month periods.
    Increased MRI scan utilisation was seen following the implementation of the redesigned pathway: original n = 50, redesigned n = 128, increasing Radiology workload. However, the redesigned pathway resulted in a reduction in time to MRI from 3h:01m to 1h:02m; reduction in time spent in ED 4h:55m to 3h:24m; reduction in time to surgery 18h:05m to 13h:38m; reduction in out-of-hour scanning from 10 to 2 patients during the evaluation period; and a reduction in on-call Orthopaedic involvement by 38%.
    All timed outcomes were improved with the implementation of this novel pathway. This suggests expediting MRI scans can result in substantial downstream benefits; albeit while increasing MRI scan utilisation. This pathway aligns with the emergency management of suspected CES under the new national CES pathway in England.
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  • 文章类型: Journal Article
    方法:观察性队列研究。
    目的:马尾综合症(CES)是一种罕见的神经系统疾病,具有潜在的破坏性后果。这项研究的目的是比较有和没有CES的患者在后路脊柱减压后2年的术后成本相关治疗。
    方法:通过分析商业保险索赔数据库,接受后路脊柱减压并同时诊断为腰椎管狭窄症的患者,神经根病,或2017年的椎间盘突出症被确认并纳入研究.主要结果是手术后2年内确定治疗的费用。治疗包括(1)物理治疗(PT),(2)止痛药,(3)注射,(4)膀胱管理,(5)肠道管理,(6)性功能障碍治疗,(7)心理治疗。
    结果:总计,3,140名患者(年龄,55.3±12.0岁;男性,62.2%)被纳入研究。确定的平均治疗总成本为每名患者2,996±6,368美元。非CES患者的确定手术的总费用为2,969±6,356美元,与CES患者的$4,535±6,898相比(P=0.079)。在确定的治疗方法中,CES患者仅PT和膀胱管理费用显着升高(PT:+115%,P<0.001;膀胱管理:+697%,P<0.001)。第一年患者之间的总成本差异显着(非CES:$1,824±3,667;CES:$3,022±4,679;P=0.020)。第二年没有发现差异。
    结论:观察到术后第一年发生的费用存在短期差异。除PT和膀胱管理外,患者之间的治疗费用相似。
    METHODS: Observational cohort study.
    OBJECTIVE: Cauda equina syndrome (CES) is a rare neurologic condition with potentially devastating consequences. The objective of this study was to compare the 2-year postoperative cost-associated treatments after posterior spinal decompression between patients with and without CES.
    METHODS: By analyzing a commercial insurance claims database, patients who underwent posterior spinal decompression with a concurrent diagnosis of lumbar spinal stenosis, radiculopathy, or disk herniation in 2017 were identified and included in the study. The primary outcome was the cost of payments for identified treatments in the 2-year period after surgery. Treatments included were (1) physical therapy (PT), (2) pain medication, (3) injections, (4) bladder management, (5) bowel management, (6) sexual dysfunction treatment, and (7) psychological treatment.
    RESULTS: In total, 3,140 patients (age, 55.3 ± 12.0 years; male, 62.2%) were included in the study. The average total cost of treatments identified was $2,996 ± 6,368 per patient. The overall cost of identified procedures was $2,969 ± 6,356 in non-CES patients, compared with $4,535 ± 6,898 in patients with CES ( P = 0.079). Among identified treatments, only PT and bladder management costs were significantly higher for patients with CES (PT: +115%, P < 0.001; bladder management: +697%, P < 0.001). The difference in overall cost was significant between patients (non-CES: $1,824 ± 3,667; CES: $3,022 ± 4,679; P = 0.020) in the first year. No difference was found in the second year.
    CONCLUSIONS: A short-term difference was observed in costs occurring in the first postoperative year. Cost of treatments was similar between patients apart from PT and bladder management.
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  • 文章类型: Case Reports
    据报道,罕见的骶外侧动脉瘤病例。这位46岁的女性在过去的15个月中出现了肠和膀胱失禁的抱怨,肛周感觉下降。她在外围医院接受了椎板切除术和椎间盘切除术,以诊断椎间盘脱出,外科医生遇到了严重而意外的出血,手术在没有有效治疗的情况下中止。既往病史包括8年前肾移植的高血压肾病。磁共振成像和血管造影结果提示骶外侧动脉瘤。有肾移植史且存在马尾神经的患者需要更彻底的评估,并应始终牢记骶外侧动脉瘤的差异。我们的目的是报告骶外侧动脉瘤的术前特征及其治疗方式。
    A rare case of aneurysm of the lateral sacral artery is reported. This 46-year-old female presented with complaints of bowel and bladder incontinence and decreased perianal sensation for the past 15 months. She underwent laminectomy and diskectomy for the diagnosis of a prolapsed disk at peripheral hospital where the surgeon was confronted with a severe and unexpected hemorrhage, and surgery was aborted without effective treatment. Prior medical history includes hypertensive kidney disease with a renal transplant eight years ago. Magnetic resonance imaging and angiographic findings were suggestive of a lateral sacral artery aneurysm. Patient with a history of renal transplant and presenting with cauda equina require a more thorough assessment, and a differential of lateral sacral artery aneurysm should always be kept in mind. Our purpose is to report the pre-operative features of the lateral sacral artery aneurysm and its treatment modalities.
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  • 文章类型: Case Reports
    背景:腰椎间盘突出症后的马尾综合症(CES)在妊娠期极为罕见,并且很少有文献概述妊娠期CES的管理。关于CES并发的围产儿妊娠管理的数据进一步有限。
    方法:一名38岁女性,在妊娠22周时,表现为向右下肢后放射的下背部疼痛恶化。她最初接受保守治疗,但又表现为神经症状恶化,包括肌束震颤和会阴麻木。磁共振成像显示L4-5大椎间盘突出,并考虑到CES,她接受了紧急减压手术,由于浅层伤口开裂而变得复杂。她最终怀孕到足月,并进行了剖腹产。在整个产后期间,通过物理治疗,患者的残余神经系统症状持续改善。
    结论:马尾综合征是一种罕见的脊柱疾病,如果不及时治疗,可能会造成破坏性后果。妊娠CES的诊断和管理与非妊娠患者相同,然而,手术患者定位的标准化,手术方法,麻醉药的使用,和胎儿的考虑是缺乏。多学科方法至关重要,尤其是在怀孕的周期胎龄。我们的案例和文献回顾表明,妊娠中期的患者可以通过俯卧位进行手术治疗,间歇性胎儿监测,和怀孕的持续管理保持不变。鉴于这些案件的罕见情况,有必要就妊娠CES患者的管理和持续护理达成共识.
    BACKGROUND: Cauda equina syndrome (CES) following lumbar disc herniation is exceedingly rare in pregnancy and there is limited literature outlining management of CES in pregnancy. There is further limited data addressing the management of periviable pregnancies complicated by CES.
    METHODS: A 38-year-old female at 22 weeks gestation presented with worsening lower back pain radiating to the right posterior lower extremity. She was initially managed with conservative therapy, but re-presented with worsening neurologic symptoms, including fasciculations and perineal numbness. Magnetic resonance imaging showed a large herniated disc at L4-5, and given concern for CES, she underwent emergent decompression surgery, which was complicated by a superficial wound dehiscence. She ultimately carried her pregnancy to term and had a cesarean delivery. The patient\'s residual neurologic symptoms continued to improve with physical therapy throughout the postpartum period.
    CONCLUSIONS: Cauda equina syndrome is a rare spinal condition with potentially devastating outcomes if not managed promptly. Diagnosis and management of CES in pregnancy is the same as in non-pregnant patients, however, standardization of patient positioning for surgery, surgical approach, anesthetic use, and fetal considerations is lacking. A multidisciplinary approach is critical, especially at periviable gestational ages of pregnancy. Our case and review of the literature demonstrates that patients in the second trimester can be managed surgically with prone positioning, intermittent fetal monitoring, and continued management of the pregnancy remains unchanged. Given the rarity of these cases, there is a need for a consensus on management and continued care in pregnant patients with CES.
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  • 文章类型: Case Reports
    肺出血(PR)是一种罕见的疾病,其特征是椎管内空气积聚。这一发现可能是由于各种原因造成的,主要是在创伤和医疗程序之后。它可以表现出各种特征,具体取决于根本原因,位置,以及空气滞留的程度。临床上,受影响患者的症状可以跨越一个范围,从无症状到表现为由压迫引起的神经根病。与肺出血相关的马尾综合征非常罕见,通常表现为大量空气,导致下脊髓神经根受压或刺激。在这份报告中,我们介绍了一名女性患者,其马尾综合征是由于腰椎硬膜外注射后意外硬膜外出血而发展的。
    Pneumorrhachis (PR) is an uncommon condition characterized by the accumulation of air within the spinal canal. This finding may occur due to various causes, mostly after trauma and medical procedures. It can manifest with various features depending on the underlying cause, the location, and the extent of the air trapped. Clinically, the symptoms in affected patients can span a spectrum, ranging from being asymptomatic to manifesting as radiculopathies resulting from compression. The pneumorrhachis-related cauda equina syndrome is incredibly rare and typically appears as a large volume of air causing compression or irritation of the nerve roots in the lower spinal cord. In this report, we present a female patient whose cauda equina syndrome developed as a result of accidental extradural pneumorrhachis after epidural injection in the lumbar spine.
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