背景:评估正电子发射断层扫描(FDGPET)在头颈部癌症初始分期和治疗中的应用。
方法:这是一项对2017年1月至2020年12月在三级教学中心接受治疗的99名初治头颈部癌症患者的回顾性研究。与横断面成像(CT和MRI)相比,根据PET扫描记录了初始分期和管理的变化。
结果:男性73例(73.7%),女性26例(26.2%),男女比例为2.8:1。总的来说,由于PET扫描,36/99(36.4%)例患者出现管理改变.关于初始分期,T,N和M阶段在14/99(14.1%)变化,19/99(19.1%)和3/99(3%)患者,分别。这些变化在原发不明的患者中明显更高(63.3%,p值-0.001)和N3(41%,p-0.045)结节性疾病。
结论:PET-CT在头颈癌的适当初始分期和后续治疗计划中起重要作用。
■初始分期PETCT改变了36.4%的病例管理。已经比较了各种不同成像模式的准确性。
BACKGROUND: To evaluate the utility of positron-emission tomography (FDG PET) in initial staging and management of head and neck cancers.
METHODS: This is a retrospective study of 99 treatment naïve head and neck cancer patients treated between January 2017 and December 2020 at a tertiary teaching centre. Change in initial staging and management was noted based on PET scan compared to cross-sectional imaging (CT and MRI).
RESULTS: There were 73 (73.7%) males and 26 (26.2%) females with male-to-female ratio of 2.8:1.Overall, change in management was seen in 36/99 (36.4%) patients due to PET scan. With regards to initial staging, T, N and M stage was changed in 14/99 (14.1%), 19/99 (19.1%) and 3/99 (3%) patients, respectively. These changes were significantly higher in patients with unknown primary (63.3%, p value -0.001) and N3 (41%, p -0.045) nodal disease.
CONCLUSIONS: PET-CT plays an important role in appropriate initial staging and subsequent treatment planning of head and neck cancers.
UNASSIGNED: Initial staging PETCT changes management in 36.4% cases. Accuracy of various different imaging modalities have been compared.