COMPUTED TOMOGRAPHY

计算机断层扫描
  • 文章类型: Journal Article
    建议将冠状动脉CT血管造影(CTA)衍生的血流储备分数(FFRCT)用于中度冠状动脉狭窄的生理评估,以指导转诊到有创冠状动脉造影(ICA)。在这项研究中,我们报告了在转诊医院实施CTA/FFRCT测试算法作为ICA看门人的可行性的实际数据.通过CTA对新出现的稳定症状和可疑冠状动脉狭窄(30-89%)的患者进行回顾性全面研究。CTA数据集的评估,FFRCT分析的解释,下游检测的决策由熟练的CT-心脏病学家进行.在3974例患者中进行了CTA,其中381人(10%)直接转诊至ICA,而非侵入性功能检测463例(12%):FFRCT375例(81%)和灌注成像88例(19%)。由于CTA图像质量不足,有8例(2%)拒绝了FFRCT分析。FFRCT后从ICA推迟的患者人数为267(71%),而100人(27%)转诊至ICA。62例(62%)患者证实了阻塞性冠状动脉疾病(CAD),53例(53%)进行了血运重建。血运重建率,n(%),在接受FFRCT引导转诊与CTA引导转诊ICA的患者中,狭窄率较高:30-69%,28(44%)对8(21%);70-89%狭窄,39(69%)对25(46%),分别,两者p<0.05。在转诊医院实施FFRCT是可行的,减少了侵入性手术的数量,提高了血运重建率。
    Coronary CT angiography (CTA) derived fractional flow reserve (FFRCT) is recommended for physiological assessment in intermediate coronary stenosis for guiding referral to invasive coronary angiography (ICA). In this study, we report real-world data on the feasibility of implementing a CTA/FFRCT test algorithm as a gatekeeper to ICA at referral hospitals. Retrospective all-comer study of patients with new onset stable symptoms and suspected coronary stenosis (30-89%) by CTA. Evaluation of CTA datasets, interpretation of FFRCT analysis, and decisions on downstream testing were performed by skilled CT-cardiologists. CTA was performed in 3974 patients, of whom 381 (10%) were referred directly to ICA, whereas 463 (12%) to non-invasive functional testing: FFRCT 375 (81%) and perfusion imaging 88 (19%). FFRCT analysis was rejected in 8 (2%) due to inadequate CTA image quality. Number of patients deferred from ICA after FFRCT was 267 (71%), while 100 (27%) were referred to ICA. Obstructive coronary artery disease (CAD) was confirmed in 62 (62%) patients and revascularization performed in 53 (53%). Revascularization rates, n (%), were higher in patients undergoing FFRCT-guided versus CTA-guided referral to ICA: 30-69% stenosis, 28 (44%) versus 8 (21%); 70-89% stenosis, 39 (69%) versus 25 (46%), respectively, both p < 0.05. Implementation of FFRCT at referral hospitals was feasible, reduced the number of invasive procedures, and increased the revascularization rate.
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  • 文章类型: Journal Article
    目的:探讨代谢综合征与肾周脂肪滞留(PRFS)的关系。在计算机断层扫描(CT)上定义为肾周脂肪中的线性或曲线软组织密度。
    方法:回顾性纳入2022年10月至2023年3月期间在单一机构进行腹部CT健康检查的成年人。两名放射科医生评估了每个CT的PRFS程度,并将其分级为缺失,轻度/中度,和严重。采用Logistic回归分析探讨PRFS与代谢综合征相关因素的关系,以及年龄和性别。
    结果:在701名参与者中(平均年龄,56.8岁±9.7;336名女性和365名男性),87例(12.4%)有轻度(n=80)或中度(n=7)PRFS。没有人患有严重的PRFS。PRFS的存在与较高的体重指数独立相关(比值比[OR],超重和肥胖的2.561和9.842,分别为;p≤0.001),有或没有抗高血压药物的血压升高(OR,2.232;p=0.015),抗糖尿病药物(或,3.129;p<0.001),和降脂药(OR,1.919;p=0.019),年龄较大(或,4.545和9.109,50-59年和≥60年,分别为;p≤0.002),和男性(或,10.065;p<0.001)。87名PRFS患者中有63名(72.4%)患有代谢综合征,614名没有PRFS的参与者中有265名(43.2%)这样做(p<0.001)。
    结论:在其他方面健康的成年人中,轻度或中度PRFS可能与代谢综合征或相关疾病的存在有关。
    OBJECTIVE: To investigate the association between metabolic syndrome and perirenal fat stranding (PRFS), which is defined as linear or curvilinear soft tissue densities in the perirenal fat on computed tomography (CT).
    METHODS: Adults who had abdominal CT for health screening at a single institution between October 2022 and March 2023 were included retrospectively. Two radiologists assessed the extent of PRFS for each CT and graded it as absent, mild/moderate, and severe. Logistic regression analyses were used to investigate the associations between PRFS and metabolic syndrome-related factors, as well as age and gender.
    RESULTS: Among 701 participants (mean age, 56.8 years ± 9.7; 336 women and 365 men), 87 (12.4%) had mild (n = 80) or moderate (n = 7) PRFS. None had severe PRFS. The presence of PRFS was independently associated with higher body mass index (odds ratio [OR], 2.561 and 9.842 for overweight and obese, respectively; p ≤ 0.001), elevated blood pressure with or without anti-hypertensive medication (OR, 2.232; p = 0.015), anti-diabetic medication (OR, 3.129; p < 0.001), and lipid-lowering medication (OR, 1.919; p = 0.019), older age (OR, 4.545 and 9.109 for 50-59 years and ≥ 60 years, respectively; p ≤ 0.002), and male gender (OR, 10.065; p < 0.001). Sixty three of 87 (72.4%) participants with PRFS had metabolic syndrome, while 265 of 614 (43.2%) participants without PRFS did (p < 0.001).
    CONCLUSIONS: Incidental mild or moderate PRFS may be associated with the presence of metabolic syndrome or related disorders in otherwise healthy adults.
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  • 文章类型: Journal Article
    背景:原发性肝淋巴瘤(PHL)是一种罕见的原发性肝肿瘤。目的探讨PHL的重要影像学特征。
    方法:回顾性分析16例经病理证实的PHL患者的CT/MR资料及临床特征。评估的影像学特征包括病变分布,生长外观,密度或信号特征,以及动态增强过程中的典型标志。
    结果:本研究共纳入16例患者,年龄从27岁到86岁不等(9名男性和7名女性;平均年龄,62年)。右上腹痛,萎靡不振,或在体检期间首次发现是主要投诉。动态对比增强CT和MRI显示13例患者(13/16,81%),3例患者多结节(3/16,19%)。病变表现为血管漂浮征10例(10/16,63%),胆管穿通征6例(6/16,37%)。在10例患者(10/16,63%)中观察到PHL坏死,并且在11例接受MRI的患者中有5例(5/11,45%)在T2WI上呈现目标体征。增强后,10例(10/16,63%)患者在动脉期出现多结节征,并在12例患者(12/16,75%)的门静脉或延迟期出现造影剂冲洗,假胶囊在延迟期15例(15/16,94%),延迟期有双环征8例(8/16,50%)。
    结论:PHL通常见于β-2-微球蛋白水平升高的老年患者。其独特的成像特征包括明显低的ADC值,胆道/血管漂浮征,延迟阶段的多结节符号和双环符号,可能有助于诊断和鉴别PHL。
    BACKGROUND: Primary hepatic lymphoma (PHL) is a rare primary liver tumor. The purpose of this study was to investigate the crucial imaging characteristics of PHL.
    METHODS: CT/MR data and clinical features of 16 patients with pathologically proven PHL were retrospectively reviewed. The assessed imaging characteristics included lesion distribution, growth appearance, density or signal characteristics, and typical signs during the dynamic enhancement.
    RESULTS: A total of sixteen patients were included in this study, ranging in age from 27 to 86 years (nine men and seven women; mean age, 62 years). Right upper abdominal pain, malaise, or first detection during physical examination were the chief complaint. Dynamic contrast-enhanced CT and MRI demonstrated focal masses in thirteen patients (13/16, 81%), and multiple nodules in three patients (3/16, 19%). The lesions showed vascular floating sign in 10 patients (10/16, 63%) and biliary pass-through sign in 6 patients (6/16, 37%). Necrosis in PHLs were observed in 10 patients (10/16, 63%) and presented target sign on T2WI in 5 out of 11 patients (5/11, 45%) undergoing MRI. After enhancement, PHLs had multinodular sign in the arterial phase in 10 patients (10/16, 63%), and presented washout of contrast medium in the portal-venous or delayed phase in 12 patients (12/16, 75%), pseudocapsule in the delayed phase in 15 patients (15/16, 94%), and double-ring sign in the delayed phase in 8 patients (8/16, 50%).
    CONCLUSIONS: PHL is generally seen in elderly patients with elevated beta-2-microglobulin levels. Its distinctive imaging features including obviously low ADC value, biliary/vascular floating sign, multinodular sign and double-ring sign in the delayed phase, may help to diagnose and differentiate PHL.
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  • 文章类型: Journal Article
    目标:头部的影像学评估是头痛护理的重要组成部分。计算机断层扫描(CT)扫描可以更详细地分析病情和更集中的护理。这项研究检查了头部CT扫描,以确定头痛患者的主要主诉是哪种异常。方法:我们评估了在加纳西部和中部地区的两个诊断机构进行的头部检查的4年CT扫描数据。我们检查了2017年1月至2020年12月以头痛为主要主诉的477例患者的数据。我们采用卡方和Fisher精确检验(如果适用)来比较不同年龄段的头部CT诊断,性别,头痛亚型,和脑损伤亚组。结果:研究中有53.5%(n=255)的女性和46.5%(n=222)的男性。患者平均年龄38.67±17.23岁,年CT诊断异常率从2017年的35.9%到2022年的45.4%不等。头部CT诊断异常与年龄组和患者性别密切相关(分别为p=0.011和p=0.009)。202名患者中,15.3%和24.3%分为颅内病变和颅外病变,分别。上颌窦炎影响了近60%的患者,而肿瘤和出血占25.2%和11.9%,分别。结论:头部CT扫描对于检测近50%患有各种程度头痛的患者的异常至关重要。鼻窦炎,脑肿瘤,出血是常见的病变。制定本地标准作业程序以促进更好地利用这类影像服务至关重要,特别是在被诊断为头痛的患者中。
    Objectives: The radiographic assessment of the head is a crucial part of headache care. A computed tomography (CT) scan enables a more detailed analysis of the condition and more focused care. This study examined head CT scans to determine what kinds of anomalies were present in patients with headaches as their primary complaint. Methods: We evaluated 4 years\' worth of CT scan data from head exams conducted at two diagnostic facilities in Ghana\'s western and central regions. We examined data on 477 patients with a headache as their primary complaint between January 2017 and December 2020. We employed chi-square and Fisher\'s exact tests (where applicable) to compare head CT diagnoses between age groups, gender, headache subtypes, and brain lesion subgroups. Results: There were 53.5% (n = 255) females and 46.5% (n = 222) males in the study. The average age of patients was 38.67 ± 17.23 years, with an annual rate of abnormal CT diagnoses ranging from 35.9% in 2017 to 45.4% in 2022. Abnormal head CT diagnoses are strongly correlated with age groups and patient gender (p = 0.011 and p = 0.009, respectively). Of the 202 patients, 15.3% and 24.3% were classified as intracranial lesions and extracranial lesions, respectively. Maxillary sinusitis affected nearly 60% of the patients, while tumors and hemorrhages affected 25.2% and 11.9%, respectively. Conclusions: A CT scan of the head is essential to detect abnormalities in nearly 50% of patients suffering from various degrees of headache. Sinusitis, brain tumors, and hemorrhage were common lesions detected. It is crucial to create local standard operating procedures to promote better utilization of this type of imaging service, particularly among patients who have been diagnosed with headaches.
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  • 文章类型: Case Reports
    伴随创伤的低温心脏骤停(HCA)提出了重大的临床管理挑战。在这些案例报告中,心脏骤停患者在体外心肺复苏(ECPR)之前进行计算机断层扫描(CT)成像,意外体温过低,和创伤。第一起案件涉及一名74岁的男性,他在寒冷的条件下在家中倒塌。到达急诊室(ED)后,他心脏骤停,核心体温为25.0°C,怀疑头部外伤。CT成像显示轻度创伤性脑损伤和双侧股骨骨折。ECPR是在CT成像后开始的,这导致了成功的复温和全面的神经恢复。第二个案例描述了一名32岁的女性从桥上跳下,在抢救过程中经历过心脏骤停,核心温度为17.4°C。ECPR前的CT成像显示无明显创伤。尽管复苏时间延长,患者表现出完全的神经系统恢复。ECPR之前的CT成像可以通过排除体温过低和严重出血性并发症之前的心脏骤停来进行适当的患者选择。由于脑代谢减少,在CT成像上延长复苏时间可能可以接受低温心脏骤停。这些罕见的病例报告证明了ECPR之前的CT成像在治疗创伤引起的低温心脏骤停中的潜在益处,并有助于适当的候选人选择和有效的干预,而不会损害神经系统的预后。
    Hypothermic cardiac arrest (HCA) with concomitant trauma presents a significant clinical management challenge. In these case reports, computed tomography (CT) imaging was performed before extracorporeal cardiopulmonary resuscitation (ECPR) in patients with cardiac arrest, accidental hypothermia, and trauma. The first case involved a 74-year-old male who collapsed outside his home under freezing conditions. Upon arrival at the emergency department (ED), he was in cardiac arrest with a core body temperature of 25.0°C and suspected head trauma. CT imaging revealed minor traumatic brain injuries and bilateral femoral fractures. ECPR was initiated after CT imaging, which led to successful rewarming and full neurological recovery. The second case describes a 32-year-old female who jumped from a bridge, experienced cardiac arrest during the rescue, and had a core temperature of 17.4°C. CT imaging before ECPR revealed no significant trauma. Despite prolonged resuscitation, the patient showed a complete neurological recovery. CT imaging before ECPR allows appropriate patient selection by ruling out cardiac arrest before hypothermia and major hemorrhagic complications. Hypothermic cardiac arrest may be acceptable for prolonged resuscitation time on CT imaging owing to reduced cerebral metabolism. These rare case reports demonstrate the potential benefits of CT imaging before ECPR in the management of hypothermic cardiac arrest with trauma and aid in appropriate candidate selection and effective intervention without compromising neurological outcomes.
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  • 文章类型: Case Reports
    神经节神经瘤是由腹膜后和后纵隔交感神经引起的罕见肿瘤。颅内三叉神经节神经瘤更罕见,到目前为止只报告了7例。我们介绍了一例65岁的男性,患有右侧抽动性头痛型和右眼失明。磁共振成像显示中颅窝有一个不明确的肿块病变,一些区域具有降低的表观扩散系数和多个微出血。通过蝶形和颞下入路进行右中开颅手术,可以实现肿瘤的零碎减积。检测到的组织学特征与三叉神经神经节神经瘤(成熟型)的组织学特征相匹配。
    Ganglioneuromas are rare tumors arising from retroperitoneal and posterior mediastinal sympathetic nerves. Intracranial trigeminal nerve ganglioneuromas are even more rare, with only seven cases reported to date. We present a case of a 65-year-old male with a right-sided throbbing headache type and blindness in his right eye. Magnetic resonance imaging revealed an ill-defined mass lesion in the middle-cranial fossa, with a few areas having a reduced apparent diffusion coefficient and multiple microhemorrhages. Piecemeal debulking of the tumor was achieved by performing a right-middle craniotomy via the pterionic and sub-temporal approach. The detected histological features matched those of a ganglioneuroma (maturing type) of the trigeminal nerve.
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  • 文章类型: Journal Article
    目的:本研究旨在建立多模态深度学习网络模型,以增强良恶性肺磨玻璃结节[GGNs]的诊断。
    方法:从中国多个中心收集肺GGNs的回顾性数据,包括北方,东北,西北,南,和中国西南部。以8:2的比率将数据分成训练集和验证集。此外,我们还从我们的医院数据库获得了一个GGN数据集,并将其用作测试集.所有患者均行胸部计算机断层扫描[CT],结节的最终诊断基于术后病理报告。残差网络[ResNet]用于提取成像数据,用于语义信息抽取的Word2Vec方法,以及结合影像特征和患者数据构建多模态分类模型的自注意方法。然后,将提出的多模式模型的诊断效率与现有的ResNet和VGG模型以及放射科医师的诊断效率进行了比较。
    结果:多中心数据集包含1020个GNS,包括265个良性结节和755个恶性结节,测试数据集包括204个GGN,67个良性结节和137个恶性结节。在验证集中,提出的多模态模型达到了90.2%的精度,灵敏度为96.6%,特异性为75.0%,超过了VGG[73.1%,76.7%,和66.5%]和ResNet[78.0%,83.3%,和65.8%]模型诊断良性和恶性结节。在测试集中,多模式模型准确诊断125个[91.18%]恶性结节,优于放射科医生[80.37%的准确率]。此外,多模态模型正确识别54[准确性,80.70%]良性结节,相比之下,放射科医生的准确率为85.47%。将放射科医师的诊断结果与多模式模型的结果与术后病理相关的一致性检验显示出很强的一致性,多模式模型显示与金标准病理结果更接近[Kappa=0.720,P<0.01]。
    结论:多模态深度学习网络模型在区分良性和恶性GGN方面表现出了有希望的诊断有效性,因此,作为辅助放射科医生提高GGN诊断准确性的参考工具具有潜力,有可能提高他们在临床环境中的工作效率。
    OBJECTIVE: This study aimed to establish a multimodal deep-learning network model to enhance the diagnosis of benign and malignant pulmonary ground glass nodules [GGNs].
    METHODS: Retrospective data on pulmonary GGNs were collected from multiple centers across China, including North, Northeast, Northwest, South, and Southwest China. The data were divided into a training set and a validation set in an 8:2 ratio. In addition, a GGN dataset was also obtained from our hospital database and used as the test set. All patients underwent chest computed tomography [CT], and the final diagnosis of the nodules was based on postoperative pathological reports. The Residual Network [ResNet] was used to extract imaging data, the Word2Vec method for semantic information extraction, and the Self Attention method for combining imaging features and patient data to construct a multimodal classification model. Then, the diagnostic efficiency of the proposed multimodal model was compared with that of existing ResNet and VGG models and radiologists.
    RESULTS: The multicenter dataset comprised 1020 GGNs, including 265 benign and 755 malignant nodules, and the test dataset comprised 204 GGNs, with 67 benign and 137 malignant nodules. In the validation set, the proposed multimodal model achieved an accuracy of 90.2%, a sensitivity of 96.6%, and a specificity of 75.0%, which surpassed that of the VGG [73.1%, 76.7%, and 66.5%] and ResNet [78.0%, 83.3%, and 65.8%] models in diagnosing benign and malignant nodules. In the test set, the multimodal model accurately diagnosed 125 [91.18%] malignant nodules, outperforming radiologists [80.37% accuracy]. Moreover, the multimodal model correctly identified 54 [accuracy, 80.70%] benign nodules, compared to radiologists\' accuracy of 85.47%. The consistency test comparing radiologists\' diagnostic results with the multimodal model\'s results in relation to postoperative pathology showed strong agreement, with the multimodal model demonstrating closer alignment with gold standard pathological findings [Kappa=0.720, P<0.01].
    CONCLUSIONS: The multimodal deep learning network model exhibited promising diagnostic effectiveness in distinguishing benign and malignant GGNs and, therefore, holds potential as a reference tool to assist radiologists in improving the diagnostic accuracy of GGNs, potentially enhancing their work efficiency in clinical settings.
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  • 文章类型: Journal Article
    顽固性咽鼓管是一种身体疾病,其中正常闭合的咽鼓管间歇性地保持开放。在文献中很少描述伴有咽鼓管异常的颈内动脉(ICA)异常。据我们所知,所提出的案例是文献中的第二种情况。在这份报告中,我们在一名51岁的女性中介绍了一例罕见的ICA异常并伴有双侧咽鼓管的情况。
    Patulous Eustachian tube is a physical disorder in which the normally closed Eustachian tube remains open intermittently. Internal carotid artery (ICA) anomalies accompanied by Eustachian tube anomalies have been described very rarely in the literature. To the best of our knowledge, the presented case is the second case in the literature. In this report, we present a rare case of ICA anomalies accompanied by a bilateral patulous Eustachian tube in a 51-year-old woman.
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  • 文章类型: Journal Article
    目的:本研究的目的是探讨股股前倾角(FAA)增大的髌骨脱位(PD)患者股内侧斜肌(VMO)是否发生代偿。
    方法:在2021年至2024年之间,我们纳入了60例复发性PD患者(RPD组)。纳入标准是至少两次PD发作,以及膝关节和髋关节的完整CT扫描。排除标准包括创伤性或习惯性脱位,以前做过膝盖手术,等。在这些病人中,将30例FAA过高(≥30°)的患者分配到A组,和30对B组没有过多的FAA(<30°)。还包括120例无髌股疾病的对照组(C组)。在CT扫描中测量VMO和股外侧肌(VLM)的横截面积,并计算VMO/VLM面积比。分析了FAA与VMO/VLM比值的相关性。
    结果:RPD组的FAA明显更大(15.0±1.9°vs.30.1±9.6°,P=0.040)和较小的VMO/VLM比率(4.2±1.5vs.与C组相比,3.5±1.0,P=0.014)。在RPD组中,A组VMO/VLM比值高于B组(4.0±1.1vs.3.0±0.7,P=0.029)。B组的VMO/VLM比值低于C组(3.0±0.7vs.4.2±1.5,P=0.004)。然而,A组与C组VMO/VLM比值无明显差别。RPD组VMO/VLM比值与FAA呈中度正相关,相关系数r=0.4(P=0.012),表明两者之间存在统计上显著的关系。
    结论:与对照组相比,复发性PD患者的VMO/VLM比率较小。在PD患者中,FAA升高与VMO的代偿性增厚和较高的VMO/VLM比率相关。这表明增加的FAA可能会驱动股四头肌的生物力学适应,稳定髌骨.临床医生在评估和治疗PD时应考虑FAA的变化。
    方法:三级。
    OBJECTIVE: The purpose of this study was to investigate whether the vastus medialis oblique (VMO) muscle compensates in patellar dislocation (PD) patients with the increased femoral anteversion angle (FAA).
    METHODS: Between 2021 and 2024, we included 60 patients with recurrent PD (RPD group). Inclusion criteria were at least two episodes of PD, as well as complete CT scans of the knee and hip. Exclusion criteria included traumatic or habitual dislocation, previous knee surgery, etc. Of these patients, 30 with excessive FAA (≥ 30°) were assigned to the A group, and 30 without excessive FAA (< 30°) to the B group. A control group of 120 patients without patellofemoral disorders was also included (C group). The cross-sectional areas of the VMO and vastus lateralis muscle (VLM) were measured 20 mm above the patella on CT scans, and the VMO/VLM area ratio was calculated. The correlation between FAA and the VMO/VLM ratio was analyzed.
    RESULTS: The RPD group had a significantly larger FAA (15.0 ± 1.9° vs. 30.1 ± 9.6°, P = 0.040) and a smaller VMO/VLM ratio (4.2 ± 1.5 vs. 3.5 ± 1.0, P = 0.014) compared to the C group. Within the RPD group, the A group had a higher VMO/VLM ratio than the B group (4.0 ± 1.1 vs. 3.0 ± 0.7, P = 0.029). The B group\'s VMO/VLM ratio was lower than that of the C group (3.0 ± 0.7 vs. 4.2 ± 1.5, P = 0.004). However, there was no significant difference in the VMO/VLM ratio between the A group and the C group. The VMO/VLM ratio showed a moderate positive correlation with FAA in the RPD group, with a correlation coefficient of r = 0.4 (P = 0.012), indicating a statistically significant relationship between the two.
    CONCLUSIONS: Patients with recurrent PD showed a smaller VMO/VLM ratio compared to controls. Increased FAA was correlated with compensatory thickening of the VMO and a higher VMO/VLM ratio in PD patients. This suggests that increased FAA may drive biomechanical adaptations in the quadriceps, stabilizing the patella. Clinicians should consider changes in FAA when assessing and treating PD.
    METHODS: Level III.
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  • 文章类型: Journal Article
    目的:评估骨外粘液样软骨肉瘤(EMC)的临床和影像学特征。
    方法:我们的病理数据库查询了EMCs病例。肿瘤位置,尺寸,成像外观,存在转移,疾病复发,并记录临床结果.影像学研究由肌肉骨骼放射科医生和骨科肿瘤学家共同评估。
    结果:30名受试者符合纳入标准(平均年龄52.7±16.2岁;19名男性,11名女性),其中17例(56.7%)有术前影像学检查。肿瘤最常见于下肢(20/30;66.7%)。所有病例均表现为软组织肿块,在XR或CT上无矿化。核磁共振成像,肿瘤在T2加权序列上通常为高信号(14/14;100%),并具有软骨样基质外观(12/14;85.7%).16例患者中有11例(68.9%)肿瘤浸润,11例患者中有2例(18.2%)坏死。所有受试者都通过病理学检查了他们的肿瘤,20名(66.7%)受试者除了诊断(肿瘤侵袭,有丝分裂率,和坏死)在病理报告中注明。平均随访时间为9.4±7.5(1.0-29.6)年。在最后一次随访中,28名受试者中有14名(50%)是无病的,28人中有6人患有持续性转移性疾病,28人中有8人死亡。
    结论:EMC是一种罕见的肉瘤,通常表现为下肢软组织肿块,MRI表现为软骨样。与传统的软骨肉瘤不同,EMC未在XR或CT上显示矿化。
    OBJECTIVE: To evaluate clinical and radiological features of extraskeletal myxoid chondrosarcomas (EMC).
    METHODS: Our pathology database was queried for cases of EMCs. Tumor location, size, imaging appearance, presence of metastases, disease recurrence, and clinical outcome were documented. Imaging studies were evaluated in consensus by a musculoskeletal radiologist and an orthopedic oncologist.
    RESULTS: Thirty subjects met the inclusion criteria (mean age 52.7 ± 16.2 years; 19 male, 11 female), 17 (56.7%) of which had pre-operative imaging. Tumors occurred most often in the lower extremities (20/30; 66.7%). All cases presented as a soft-tissue mass without mineralization on XR or CT. On MRI, tumors were typically hyperintense on T2-weighted sequences (14/14; 100%) and had a chondroid matrix appearance (12/14; 85.7%). Tumor invasion was observed in 11 out of 16 (68.9%) patients and necrosis in 2 out of 11 subjects (18.2%). All subjects had their tumors examined by pathology, and 20 (66.7%) subjects also had descriptive information in addition to the diagnosis (tumor invasion, mitotic rate, and necrosis) noted in the pathology reports. The mean duration of follow-up was 9.4 ± 7.5 (1.0 - 29.6) years. At the last follow-up, 14 out of 28 (50%) subjects were disease-free, 6 out of 28 had persistent metastatic disease and 8 out of 28 had died.
    CONCLUSIONS: EMC is a rare sarcoma that commonly presents as lower extremity soft tissue mass with chondroid appearance on MRI. Unlike conventional chondrosarcomas, EMC do not demonstrate mineralization on XR or CT.
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