伯基特淋巴瘤是一种非霍奇金B细胞淋巴瘤,在儿科人群中患病率很高。腹部表现在散发性Burkitt淋巴瘤中是众所周知的,从非特异性症状到肠套叠引起的肠梗阻各有不同;然而,几乎没有描述过块状脾受累。
目的:介绍一例脾肿块患者,其组织病理学分析显示Burkitt淋巴瘤。
方法:一名13岁女性患者出现腹痛,逐步减肥,和发烧。影像学检查显示有脾肿块,肠增厚,和回肠肠套叠.脾活检的组织病理学分析显示Burkitt淋巴瘤。第一周期化疗(BFM95-NHL方案)后,腹部症状得到缓解;没有观察到其他提示肠套叠的体征,以及观察到脾质量显着减少。
结论:Burkitt淋巴瘤在儿科患者中可以表现为明确的脾肿瘤,不会导致脾肿大.此外,它的管理不需要手术,因为它可以通过化疗解决。
Burkitt lymphoma is a non-Hodgkin B-cell lymphoma with a high prevalence in the pediatric population. Abdominal manifestations are well known in sporadic Burkitt lymphoma and vary from nonspecific symptoms to intestinal obstruction due to intussusception; however, mass-like splenic involvement has been scarcely described.
OBJECTIVE: To present a case of a patient with a splenic mass whose histopathological analysis revealed Burkitt lymphoma.
METHODS: A 13-year-old female patient presented with abdominal pain, progressive weight loss, and fever. Imaging studies showed a splenic mass, intestinal thickening, and ileal intussusception. Histopathological analysis of spleen biopsy revealed Burkitt lymphoma. After the first cycle of chemotherapy (BFM95-NHL protocol), abdominal symptoms resolved; no other signs suggestive of intussusception were observed, as well as a significant reduction of the splenic mass was observed.
CONCLUSIONS: Burkitt lymphoma in pediatric patients can present as a well-defined splenic tumor, causing no splenomegaly. In addition, its management does not require surgery since it can be resolved with chemotherapy.