未经授权:报告一例眼部青少年黄色肉芽肿(JXG)病例,角膜混浊,和正常眼压(IOP)在新生儿期和Ahmed青光眼阀(AGV)植入术治疗。
未经证实:JXG是一种罕见的疾病,主要见于婴儿,但是新生儿的表现非同寻常。尽管自发性前房积血是JXG的常见表现,仅在1例中报告了新生儿期的Buthemos和角膜混浊,在演示时具有较高的IOP值。
未经证实:16天大的男性患者出现了bopthalmos,弥漫性角膜混浊,右眼IOP值11mmHg。三周后眼压上升到28mmHg,自发性前房积血,抗青光眼药物和外用皮质类固醇均无反应。AGV被植入,术后眼压降至13mmHg。在后续行动中,在全身麻醉下检查时,患者皮肤上发现了许多坚硬的黄色结节。皮肤结节的组织病理学检查与JXG的诊断相符。在随访过程中出现了晶状体半脱位和牙齿畸形,并通过平坦部晶状体切除术进行了处理。经过三个月的沉默,在侧端口入口周围确定了上皮向内生长。不幸的是,向内生长对冷冻治疗没有反应,并导致肺结核。眼球摘除后眼的病理评估显示后节段受累。
UASSIGNED:眼部JXG可以与Buththalmos一起出现,角膜混浊,和正常的IOP值,在新生儿期没有任何皮肤损伤。新生儿JXG的出现可能与有限的药物治疗反应和侵袭性病程有关。
未经评估:本病例报告介绍了第二个眼JXG病例,表现为白眼和角膜混浊,文献中第三个经病理证实的JXG后段受累。
未经批准:DericiogluV,SevikMO,EraslanM,etal.幼年黄色肉芽肿在新生儿期表现为Buthromos和角膜浑浊:一例病例报告。JCurr青光眼Pract2022;16(2):128-131。
UNASSIGNED: To report an ocular juvenile xanthogranuloma (JXG) case presented with
buphthalmos, corneal cloudiness, and normal intraocular pressure (IOP) in the neonatal period and treated with Ahmed glaucoma valve (AGV) implantation.
UNASSIGNED: JXG is a rare disorder predominantly seen in infants, but the neonatal presentation is extraordinary. Although spontaneous hyphema is a common presenting sign in JXG,
buphthalmos and corneal opacity in the neonatal period were reported only in one case, which had high IOP values at presentation.
UNASSIGNED: Sixteen-day-old male patient presented with
buphthalmos, diffuse corneal clouding, and 11 mm Hg of IOP value in the right eye. IOP increased to 28 mm Hg three weeks later, and spontaneous hyphema developed, which did not respond to antiglaucomatous medications and topical corticosteroids. AGV was implanted, and the IOP decreased to 13 mm Hg postoperatively. In the follow-ups, numerous firm yellowish nodules were noticed on the patient\'s skin during the examination under general anesthesia. Histopathological examination of the skin nodules was compatible with the diagnosis of JXG. Lens subluxation and phacodonesis were developed during the follow-up and were managed with pars plana lensectomy. After a silent period of 3 months, epithelial ingrowth was determined around the side port entrance. Unfortunately, the ingrowth did not respond to cryotherapy and resulted in phthisis bulbi. Pathological evaluation of the enucleated phthisic eye revealed posterior segment involvement.
UNASSIGNED: Ocular JXG can be present with
buphthalmos, corneal opacity, and normal IOP values without any skin lesions in the neonatal period. Neonatal presentation of JXG may be associated with limited medical therapy response and aggressive disease course.
UNASSIGNED: This case report introduces the second ocular JXG case, which presented with buphthalmos and corneal cloudiness, and the third pathologically proven posterior segment involvement of JXG in the literature.
UNASSIGNED: Dericioglu V, Sevik MO, Eraslan M, et al. Juvenile Xanthogranuloma Presented with
Buphthalmos and Corneal Clouding in Neonatal Period: A Case Report. J Curr Glaucoma Pract 2022;16(2):128-131.