Breast lump

乳房肿块
  • 文章类型: Case Reports
    原发性乳腺结核是肺外结核范畴下的罕见疾病。它倾向于影响育龄女性,而不是绝经后妇女或青春期前女孩。这种罕见的疾病形式对诊断提出了挑战,因为成像可以模拟良性和恶性乳腺病变的外观。我们描述了一名年轻女性的原发性乳腺结核病例,该病例表现为持续的左乳房肿块。被诊断为慢性左乳腺脓肿.病变的组织病理学检查与肉芽肿性乳腺炎一致,继发于结核分枝杆菌感染。患者接受了为期6个月的抗结核药物治疗,并在连续超声成像中完全缓解了症状和左乳腺病变。
    Primary breast tuberculosis is a rare disease under extrapulmonary tuberculosis category. It tends to affect females of reproductive age rather than postmenopausal women or prepubescent girls. This rare form of disease poses a challenge in diagnosing as imaging can mimic the appearance of both benign and malignant breast lesions. We describe a case of primary breast tuberculosis in a young female who presented with a persistent left breast lump. and was diagnosed with chronic left breast abscess. Histopathological examination of the lesion was consistent with granulomatous mastitis, secondary to mycobacterium tuberculosis infection. The patient was treated with a 6-month course of anti-tuberculosis drug with complete resolution of the symptoms and the left breast lesion on serial ultrasound imaging.
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  • 文章类型: Journal Article
    乳腺癌是一种普遍的全球健康问题,其特征是乳腺组织中细胞生长不受控制。2020年,全球报告了约230万例病例。2018年,印度记录了162,468例新病例和87,090例死亡。早期诊断对于降低死亡率至关重要。我们的研究集中在使用诸如甘油三酸酯-血糖指数和血液学标志物之类的标志物来区分良性和恶性乳腺肿块。
    一项前瞻性横断面研究包括有乳房肿块主诉的女性患者。目标样本大小为200。数据收集包括病史,临床乳房检查,乳房X线照相术,通过细针穿刺细胞学(FNAC)进行细胞学评估,和血液样本收集。分析的参数包括中性粒细胞与淋巴细胞比率(NLR),血小板与淋巴细胞比值(PLR),和甘油三酯血糖指数(TyG)。组织病理学检查证实了FNAC结果。统计分析,包括倾向得分匹配,Kolmogorov-Smirnov测试,Mann-WhitneyU测试,接收者的操作者曲线(ROC)分析,采用SPSS和R软件建立Logistic回归模型。对25名参与者进行了额外的验证。
    这项研究包括200名参与者。良性肿瘤109例,恶性肿瘤91例。倾向得分匹配平衡协变量。NLR在两组之间没有显着差异,而PLR和TyG指数差异显著。NLR与乳腺癌分期密切相关,但不是BI-RADS得分。PLR和TyG指数与BI-RADS评分呈中度正相关。ROC分析用于确定PLR和TyG指数的最佳截断值。结合PLR和TyG指数的Logistic回归模型可显著改善恶性肿瘤预测。
    TyG指数和PLR显示出作为区分乳腺肿块的辅助标记的潜力。NLR与癌症分期相关,但与病变类型无关。结合TyG和PLR改进了预测,协助临床决策,但临床实施需要大规模多中心试验和长期验证.
    UNASSIGNED: Breast cancer is a prevalent global health concern characterized by uncontrolled cell growth in breast tissue. In 2020, approximately 2.3 million cases were reported worldwide, with 162,468 new cases and 87,090 fatalities documented in India in 2018. Early diagnosis is crucial for reducing mortality. Our study focused on the use of markers such as the triglyceride-glycemic index and hematological markers to distinguish between benign and malignant breast masses.
    UNASSIGNED: A prospective cross-sectional study included female patients with breast mass complaints. The target sample size was 200. Data collection included medical history, clinical breast examination, mammography, cytological assessment via fine-needle aspiration cytology (FNAC), and blood sample collection. The analyzed parameters included neutrophil-to-lymphocyte Ratio (NLR), platelet-to-lymphocyte Ratio (PLR), and triglyceride-glycemic index (TyG). Histopathological examination confirmed the FNAC results. Statistical analysis including propensity score matching, Kolmogorov-Smirnov tests, Mann-Whitney U tests, receiver\'s operator curve (ROC) analysis, and logistic regression models was conducted using SPSS and R Software. Additional validation was performed on 25 participants.
    UNASSIGNED: This study included 200 participants. 109 had benign tumors and 91 had malignant tumors. Propensity score matching balanced covariates. NLR did not significantly differ between the groups, while PLR and TyG index differed significantly. NLR correlated strongly with the breast cancer stage, but not with the BI-RADS score. PLR and TyG index showed moderate positive correlations with the BI-RADS score. ROC analysis was used to determine the optimal cutoff values for PLR and TyG index. Logistic regression models combining PLR and TyG index significantly improved malignancy prediction.
    UNASSIGNED: TyG index and PLR show potential as adjunctive markers for distinguishing breast masses. NLR correlated with cancer stage but not lesion type. Combining TyG and PLR improves prediction, aiding clinical decisions, but large-scale multicenter trials and long-term validation are required for clinical implementation.
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  • 文章类型: Journal Article
    背景技术乳腺癌是世界上女性癌症死亡的主要原因。及时发现对降低死亡率很重要。在各种筛查方式中,自我乳房检查是一个简单的建议,廉价的方法,尤其是在低资源环境中。目的了解女性对自我乳房检查的看法,分析自我乳房检查的益处和障碍。方法研究参与者总数为100人。在获得知情同意后,使用半结构化问卷对研究参与者进行了访谈,调查他们对自我乳房检查的看法以及进行检查的益处和障碍.结果在研究参与者中,66%的女性知道自我乳房检查。只有8%的人知道开始自我乳房检查的年龄。18%的女性认为缺乏隐私是障碍,而尴尬是障碍的14%。几乎所有人(99%)都认为每个月完成一次自我乳房检查可以帮助他们尽早发现乳房肿块。结论参与者对自我乳房检查这一术语有合理的认识。但是明确的程序,开始考试的年龄和考试的变化都是未知的,因此必须在社会层面加以强调。克服障碍并接受自我乳房检查的好处对于将这种检查作为常规做法是必要的。
    Background Breast cancer is the leading cause of cancer death among women in the world. Timely detection is important to reduce the rate of deaths. Among the various screening modalities, self-breast examination is suggested as an easy, inexpensive method, especially in low-resource settings. Objective To understand women\'s perspective on self-breast examination and analyze the benefits and barriers of self-breast examination. Method The total number of study participants was 100. After obtaining informed consent, the study participants were interviewed using a semi-structured questionnaire on their perspective towards self-breast examination along with the benefits and barriers of performing the examination. Results Among the study participants, 66% of women were aware of self-breast examination. Only 8% were aware of the age to begin self-breast examination. Lack of privacy was considered as a barrier in 18% of women and embarrassment as a barrier was 14%. Almost all (99%) agreed that completing a self-breast examination each month may help them find breast lumps early. Conclusion The participants were reasonably aware of the term self-breast examination. But the clearcut procedure, the age to begin the examination and changes to be picked up on the examination were all unknown and hence must be emphasized at the society level. Overcoming the barriers and accepting the benefits of self-breast examinations are necessary to adopt this examination as a regular practice.
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  • 文章类型: Journal Article
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  • 文章类型: Case Reports
    本报告讨论了一例27岁女性,其组织病理学检查结果为多发性表皮包涵囊肿(EIC)与纤维腺瘤共存,而没有任何乳腺皮肤受累。EIC应作为乳腺良性病变的鉴别诊断之一。放射学评估,手术切除和组织病理学检查,仍然是EIC管理的黄金标准。本报告旨在提高对乳腺实质中EIC存在的认识水平,以及它与纤维腺瘤等其他良性乳腺病变共存或产生的可能性。
    This report discusses a case of a 27-year-old female with histopathological examination results of multiple epidermal inclusion cysts (EICs) coexisting with fibroadenoma without any involvement of breast skin. EIC should be considered as one of the differential diagnoses for benign breast lesions. Radiological evaluation, with surgical excision and histopathologic examination, remains the gold standard for the management of EIC. This report aims to increase the level of awareness on the existence of EIC in the breast parenchyma and the possibility of it coexisting with or arising from other benign breast lesions like fibroadenoma.
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  • 文章类型: Case Reports
    Dirofilaria,通常被称为心虫,是一种寄生线虫,主要感染犬。然而,据报道,人类感染可以在身体的不同部位表现为皮下结节。我们介绍了一个43岁的女性,她出现了一个乳房肿块,最终被诊断为丝虫病感染,在人类中罕见的情况。此病例报告显示,在不寻常的表现中考虑寄生虫至关重要,特别是在已知此类感染患病率高的地区。
    Dirofilaria, commonly known as heartworm, is a parasitic nematode that primarily infects canines. However, human infections have been reported and can present as subcutaneous nodules in different parts of the body. We present a case of a 43-year-old female who presented with a breast lump that was ultimately diagnosed as a Dirofilaria infection, a rare occurrence in humans. This case report shows that considering parasites in unusual presentations is of utmost importance, especially in regions known to have a high prevalence of such infections.
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  • 文章类型: Case Reports
    人囊虫病可以影响体内的任何组织或器官,并且可能是无症状的或表现出临床体征和症状,具体取决于发现囊虫的身体区域。然而,同时,囊虫病累及乳房是一种极为罕见的现象,以前发表的病例报告很少。在这份报告中,我们介绍了一名26岁已婚妇女的病例,她有无痛性左乳房肿胀的病史。
    Human cysticercosis can affect any tissue or organ in the body and may be asymptomatic or manifest clinical signs and symptoms depending on the area of the body where cysticerci are found. However, at the same time, the involvement of the breast by cysticercosis is an extremely rare phenomenon, with very few case reports published before. In this report, we present the case of a 26-year-old married woman who came with a history of painless swelling in the left breast.
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  • 文章类型: Journal Article
    乳腺肿块中肉芽肿性乳腺炎和胶原性球的共存是一个罕见的发现。对细胞形态学特征的认识可以帮助证实细胞学诊断。一位老年女性可触知的乳房肿块值得紧急关注,细针抽吸是一种快速的方法,可靠的评价方法。对一名老年女性进行细针穿刺细胞学检查(FNAC)。涂片显示有畸形肉芽肿,炎性细胞和均质透明基质球状元素与良性导管上皮细胞和肌上皮细胞混合。
    The co-existence of granulomatous mastitis and collagenous spherulosis in a breast lump is an uncommon finding. The awareness of cytomorphological features can help corroborate a cytological diagnosis. A palpable breast lump in an elderly female warrants urgent attention and fine needle aspiration is a rapid, reliable method of evaluation. An elderly female with a firm breast lump mimicking malignancy was subjected to fine needle aspiration cytology (FNAC). Smears showed ill-formed granulomas, inflammatory cells and homogeneous hyaline stromal globular elements intermingled with the benign ductal epithelial and myoepithelial cells.
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