Actinomycosis is common in the head and neck region but rarely occurs in the nasal septum. A 75-year-old male patient with an edentulous maxilla, hypertension, and diabetes developed actinomycosis confined to the nasal septum and showed mucosal necrosis and septal bony sequestration. The patient underwent surgery and medication therapy; this case was reported using endoscopic photographs and radiographs and a literature review was conducted to provide further context and understanding of the condition of the patient.

We report a case of a 67-year-old female patient that presented to the emergency department with complete right facial paralysis, progressive hearing loss and chronic otorrhea. A unique finding on CT scan is reported: a \"floating labyrinth\" - cochlea, vestibule and semicircular canals extensively surrounded by soft tissue density material but with intact thinned otic capsule walls. A transotic approach was performed for removal of noncholesteatomatous inflammatory tissue; intravenous antibiotics and corticosteroids led to partial recovery of facial nerve function. A chronic suppurative otitis media with necrotic osteomyelitis and bony sequestrum in a severe context of AIDS is the likely cause. An immunosuppressive disease should be suspected in atypical presentations of chronic suppurative otitis media without cholesteatoma.

A patient suffering from acute promyelocytic leukemia (APL) was referred to the dental department before introduction of chemotherapy by all-trans retinoic acid and arsenic trioxide (ATO). A panoramic radiography showed his third upper maxillary left tooth included into the maxillary bone. The patient presented with a febrile episode. Consequently, the infectious gateway was researched. A left maxillary sinus migration of his third upper left tooth together with a bony sequestrum has been observed on a CT-scan. A surgery was then performed to remove the bony sequestrum and the tooth. The first hypothesis of tooth migration could be that the patient had an infection prior to introduction of chemotherapy. However, neither clinical or radiographic signs were observed during the initial check-up. The second hypothesis is that ATO caused osteonecrosis of the jaw (ONJ) induced the formation of a bony sequestrum associated to the tooth migration into the sinus. ONJ could be a potential adverse of ATO chemotherapy.