Blepharoptosis

上睑下垂
  • 文章类型: Letter
    在Daungsupawong等人最近给编辑的一封信中。在美容整形外科,标题为“关于上睑下垂实用指南的ChatGPT和临床问题:对应,“作者强调了关于输入和输出参考之间输入语言差异的重要观点。然而,高级版本,如GPT-4,已经显示出英语和汉语输入之间的边际差异,可能是因为使用了更大的训练数据。为了解决这个问题,已经开发了面向非英语语言的大型语言模型(LLM)。LLM引用现有参考文献的能力各不相同,有了较新的型号,例如GPT-4,显示出比GPT-3.5更高的参考率。未来的研究应专注于解决当前的局限性,并提高新兴的LLM在为多种语言的医学问题提供准确和翔实的答案方面的有效性。证据级别V本期刊要求作者为每篇文章分配一个级别的证据。对于这些循证医学评级的完整描述,请参阅目录或在线作者说明www。springer.com/00266.
    In a recent Letter to the Editor authored by Daungsupawong et al. in Aesthetic Plastic Surgery, titled \"ChatGPT and Clinical Questions on the Practical Guideline of Blepharoptosis: Correspondence,\" the authors emphasized important points regarding the input language differences between input and output references. However, advanced versions, such as GPT-4, have shown marginal differences between English and Chinese inputs, possibly because of the use of larger training data. To address this issue, non-English-language-oriented large language models (LLMs) have been developed. The ability of LLMs to refer to existing references varies, with newer models, such as GPT-4, showing higher reference rates than GPT-3.5. Future research should focus on addressing the current limitations and enhancing the effectiveness of emerging LLMs in providing accurate and informative answers to medical questions across multiple languages.Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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  • 文章类型: Journal Article
    背景:动眼神经麻痹(ONP)通常在眼科发现,表现为同侧下垂,眼球在固定的外部展位,或伴随着有限的向内,向上,和向下运动。本病例报告描述了电针(EA)对化疗后患有ONP的乳腺癌患者的影响。
    方法:一名56岁的乳腺癌患者表现为严重上睑下垂和固定的右眼外斜视。此外,向内移动是具有挑战性的,向上,向下,并伴有明显的复视。
    方法:乳腺癌患者被诊断为ONP,化疗史。
    方法:患者被引入针灸科接受电针治疗。
    结果:经过12次EA治疗,上睑下垂症状明显改善,右上眼睑可以像左眼一样自主抬起。此外,患者的右侧眼可以自由移动,复视症状消失了.
    结论:病例提示EA可能是ONP的有效替代治疗方法。
    BACKGROUND: Oculomotor nerve palsy (ONP) is often discovered in the ophthalmology department, manifested as ptosis with the same side, eyeball in the fixed external booth, or accompanied by limited inward, upward, and downward movements. The present case report described the effect of electroacupuncture (EA) on a breast cancer patient with ONP after chemotherapy.
    METHODS: A 56-year-old breast cancer patient presented with severe ptosis and fixed right eye exotropia. Besides, it is challenging to perform the movement inward, upward, and downward, and with obvious diplopia.
    METHODS: The breast cancer patient was diagnosed with ONP, chemotherapy history.
    METHODS: The patient was introduced to acupuncture department to receiving EA treatment.
    RESULTS: After 12 times of EA treatments, the symptom of ptosis was significantly improved, and the right upper eyelid can lift autonomously as same as the left eye. Besides, the patient\'s right lateral eye could move freely, and the symptoms of double vision disappeared.
    CONCLUSIONS: The case suggests that EA may be an effective alternative treatment for ONP.
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  • 文章类型: Case Reports
    填充剂注射到上眼睑可能导致提上睑膜纤维化和上睑下垂。必须考虑这种风险。当眼睑出现时,治疗可能很困难。了解上眼睑的解剖结构和程序对于防止眼睑损伤至关重要。
    眼睑下垂是整容手术中的一种常见病,是由于上睑提肌功能障碍或Müller肌肉活动不足而发生的。其特征在于,当在眼睛水平处看到时,上眼睑边缘看起来比通常低。眼睑下垂可分为先天性和获得性。先天性上下垂的主要原因归因于提上睑肌或控制其的运动神经支配的异常。这种情况是由于动眼系统的非典型发育和故障引起的。获得性上睑下垂可分为许多类别,包括创伤性,神经性,生肌,老年,机械,和假下垂。目前,很少有文献记载上眼睑肌肉的膜膜变性导致上睑下垂。我们收到了一例由提上睑膜膜纤维化引起的下垂。我们使用提上睑肌技术取得了巨大的进步。向上提肌-穆勒肌肉折叠,以通过向上提肌的高度进步来创建稳定的复合结构。
    UNASSIGNED: Filler injections into the upper eyelid may cause levator aponeurosis fibrosis and ptosis. This risk must be considered. When ptosis appears, treatment might be difficult. Understanding the upper eyelid anatomy and procedures is essential to prevent eyelid damage.
    UNASSIGNED: Ptosis is a prevalent condition in cosmetic surgery that occurs due to malfunction of the levator palpebrae superioris or insufficient Müller muscle action. It is characterized by the upper eyelid edge appearing lower than usual when seen at eye level. Ptosis may be categorized into congenital and acquired forms. The primary cause of congenital ptosis is attributed to abnormalities of the levator palpebrae superioris muscle or the motor nerve innervation that controls it. The condition arises from atypical development and malfunction of the oculomotor system. Acquired ptosis may be classified into many categories including traumatic, neurogenic, myogenic, senile, mechanical, and fake ptosis. Currently, there is little documentation of ptosis resulting from the degeneration of the aponeurosis of the muscle in the upper eyelid. We received a case of ptosis caused by fibrosis of the levator palpebrae superioris aponeurotic membrane. We used the technique of levator palpebrae superioris great advancement. The levator palpebrae superioris-Müller muscle was folded to create a stable composite construction via the levator palpebrae superioris high progress.
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  • 文章类型: Journal Article
    检查结膜-Müller肌肉切除术(CMMR)和眼睑成形术手术后眼睑下垂和皮肤松弛症患者的泪液氧化应激水平和泪膜功能的变化。
    这项前瞻性研究包括32名健康对照和62名眼睑下垂或皮肤松弛症患者。20只眼进行了CMMR手术,42只眼进行了上眼睑成形术。通过酶联免疫吸附测定对泪液氧化应激标志物(8-羟基-2'-脱氧鸟苷[8-OHdG]和4-羟基-2-壬烯醛[4-HNE])进行定量,并在术前和术后1和6个月评估泪膜功能。在对照组中在相同的时间点进行相同的评估。
    健康对照组的术前泪液8-OHdG和4-HNE水平较低(52.8±13.5ng/mL和27.8±6.4ng/mL,分别)与皮肤松弛症患者(86.1±37.2ng/mL和29.8±11.1ng/mL,分别)和上睑下垂(90.4±39.3ng/mL和43.1±4.2ng/mL,分别)(p<0.001)。8-OHdG水平在CMMR后1个月增加,而眼睑成形术组术后1个月两种标志物均下降(p=0.034)。两组患者的Schirmer1和OSDI评分在整个访视过程中没有变化,但在CMMR后观察到泪液破裂时间(TBUT)暂时减少(p=0.017).
    皮肤松弛症和上睑下垂与较高的泪液氧化应激水平相关。CMMR手术在术后第一个月引起TBUT评分的暂时降低和氧化应激的增加。
    To examine changes in tear oxidative stress levels and tear film functions in patients with blepharoptosis and dermatochalasis following conjunctiva-Müller muscle resection (CMMR) and blepharoplasty surgeries.
    This prospective study included 32 healthy controls and 62 patients with blepharoptosis or dermatochalasis. CMMR surgery was performed in 20 eyes and upper blepharoplasty was performed in 42 eyes. Tear oxidative stress markers (8-hydroxy-2’-deoxyguanosine [8-OHdG] and 4-hydroxy-2-nonenal [4-HNE]) were quantified by enzyme-linked immunosorbent assay and tear film functions were evaluated preoperatively and at 1 and 6 months postoperatively. The same assessments were performed in the control group at the same time points.
    Preoperative tear 8-OHdG and 4-HNE levels were lower in healthy controls (52.8±13.5 ng/mL and 27.8±6.4 ng/mL, respectively) compared to patients with dermatochalasis (86.1±37.2 ng/mL and 29.8±11.1 ng/mL, respectively) and blepharoptosis (90.4±39.3 ng/mL and 43.1±4.2 ng/mL, respectively) (p<0.001). 8-OHdG levels were increased at 1 month after CMMR, while both markers were decreased 1 month postoperatively in the blepharoplasty group (p=0.034). Schirmer 1 and OSDI scores did not change throughout the visits in both patient groups, but a temporary decrease in tear break-up time (TBUT) was observed after CMMR (p=0.017).
    Dermatochalasis and blepharoptosis were associated with higher tear oxidative stress levels. CMMR surgery caused a temporary decrease in TBUT scores and an increase in oxidative stress in the first postoperative month.
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  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    背景:上睑下垂是眼科临床的常见症状,但是眼睑下垂时微笑的眼睑退缩是一种罕见的表现。在这里,我们报告了一种新颖的表现,即单眼先天性上清液患者在微笑过程中眼睑退缩。
    方法:一名10岁女孩,患有孤立和轻度的单侧先天性上睑下垂,当微笑时,眼睛的眼睑退缩,向下凝视时眼睑滞后。除近视和散光外,她没有任何系统性和眼部疾病。微笑时的眼睑缩回为5毫米,导致双侧睑裂高度有显著差异。至于上眼睑,是温和的。与反射距离1的边缘在右眼(上眼睑眼)上为1.0mm,在左眼上为3.0mm。右侧注意到向下凝视的盖子滞后1.0毫米,她睡觉时可以完全闭上眼睛。冰袋测试,甲状腺功能实验室检查,眶神经和眼运动神经的全外显子组测序(WES)和磁共振成像(MRI)结果显示正常.6个月后她的症状有所缓解,微笑时的右上眼睑缩回约3毫米,因此,微笑时的睑裂高度差异小于初始演示时的差异。
    结论:眼睑下垂可能伴有神经支配异常,这种现象可以随着年龄的增长而缓解。应该仔细检查提上睑肌功能测试的结果,以确定它是否是神经支配眼睑受损的下垂。
    BACKGROUND: Blepharoptosis is a common symptom in ophthalmology clinic, but eyelid retraction when smiling in a ptosis eye is a rare manifestation. Here we report a novel manifestation that eyelid retraction during smiling in a patient with monocular congenital ptosis.
    METHODS: A 10-year-old girl with isolated and mild unilateral congenital ptosis showed eyelid retraction in ptotsis eye when smiling together with a lid lag on downgaze. She didn\'t have any systematic and ocular diseases other than myopia and astigmatism.Eyelid retraction during smiling is 5 mm, resulting in a significant difference in the height of bilateral palpebral fissures.As for ptosis, is mild.The margin to reflex distance 1 is 1.0 mm on the right eye(ptosis eye) and 3.0 mm on the left eye. A lid lag of 1.0 mm on downward gaze was noted on the right, she could close her eyes fully while sleeping.The ice pack test, laboratory test for thyroid function, whole-exome sequencing (WES) and magnetic resonance imaging(MRI) of the orbital and ocular motor nerves showed normal results.Her symptoms alleviated after 6 months, with the retraction of the right upper eyelid when smiling was approximately 3 mm, thus the difference in the palpebral fissure height when smiling was smaller than that at the initial presentation.
    CONCLUSIONS: Blepharoptosis may accompanied with abnormal innervation like eyelid retraction, this phenomenon can be alleviated with age.The results of the levator muscle function test should be carefully examined to determine whether it is ptosis in an impaired innervation eyelid.
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  • 文章类型: Case Reports
    我们描述了眼科文献中报道的第一例17个月大男孩患有双侧视力威胁性下垂的手术治疗,tarsomegaly,外翻,和可疑过度生长综合征继发的euryblepharon。我们详细阐述了与手术管理相关的主要挑战,包括超大组织的自然和不对称生长,形成疤痕和形成混乱组织的可能性很高,以及这些可能有损害气道等关键结构的病变的患者频繁插管的风险。最终,如果视力或眼部健康受到威胁,则主要鼓励手术干预,其次是为了获得良好的美容效果。
    We describe the first case reported in ophthalmological literature of the surgical management of a 17-month-old boy with bilateral vision-threatening ptosis, tarsomegaly, ectropion, and euryblepharon secondary to suspected overgrowth syndrome. We elaborate on the major challenges associated with surgical management including the natural and asymmetric growth of oversized tissue, the high likelihood of scarring and formation of disorganized tissue, and risks of frequent intubation in these patients who may have lesions that compromise critical structures such as the airway. Ultimately, surgical intervention is encouraged primarily if vision or ocular health is threatened and secondarily to achieve good cosmesis.
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  • 文章类型: Journal Article
    背景:直接抬升是有用的,但在眉毛上方留下疤痕。我们提出了一种双平面抬升术,以避免面部疤痕,同时有效解决年轻和年轻成年患者的眉头下垂。
    方法:7例面神经麻痹患者在2018年7月至2022年6月期间接受了双平面划伤。术后平均随访时间为31.9个月。发际线的皮肤切除与向下到眉下边缘的皮下解剖相结合,以“抬起”眉头。筋膜条固定在眉毛下方的真皮上,以“握住”眉毛,条通过骨膜下隧道向上悬挂并固定在骨膜上。比较手术前后以及对侧的眉高。
    结果:报告的并发症包括受体部位的轻微血肿,暂时难以闭上眼睛,和筋膜供体部位的血清肿。瘫痪侧在术前期间和术后月(POM)3、6和12之间显示出显着差异,但在POM3和6、6和12或3和12之间的间隔中未显示出差异。瘫痪侧和非瘫痪侧之间的眉毛高度差异在术前是显着的,但在POM3、6或12时则没有。所有的伤疤都成熟了,在前额区域看不到筋膜轮廓。
    结论:双平面抬升可以使用阔筋膜进行刚性悬挂,并切除松弛的皮肤而不会留下面部疤痕,产生优异的化妆品质量和稳定的长期结果。
    BACKGROUND: Direct browlift is useful but leaves a scar above the brow. We proposed a dual-plane browlift to avoid facial scarring while effectively resolving brow ptosis in young and young adult patients.
    METHODS: Seven patients with facial palsy underwent dual-plane browlift between July 2018 and June 2022. The mean postoperative follow-up period was 31.9 months. Skin resection at the hairline was combined with subcutaneous dissection down to the inferior margin of the brow to \"lift\" the brow. Fascia lata strips were fixed to the dermis just inferior to the eyebrow to \"hold\" the brow, and the strips were suspended upward through the subperiosteal tunnel and fixed to the periosteum. Brow height was compared before and after the procedure and with the contralateral side.
    RESULTS: The reported complications included slight hematoma at the recipient site, temporary difficulty in closing the eye, and seroma at the fascia donor site. The paralyzed side showed significant differences between the preoperative period and postoperative months (POM) 3, 6, and 12, but differences were not shown in the intervals between POM 3 and 6, 6 and 12, or 3 and 12. The difference in eyebrow height between the paralyzed and nonparalyzed sides was significant preoperatively but not at POM 3, 6, or 12. All scars matured well, and the fascia silhouette was not visible in the forehead region.
    CONCLUSIONS: Dual-plane browlift enables rigid suspension using the fascia lata and excises flaccid skin without leaving facial scars, yielding excellent cosmetic quality and stable long-term outcomes.
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  • 文章类型: Journal Article
    描述使用聚丁酸酯涂层聚酯缝合线(Ethibond)悬吊后延迟感染的发生率和管理。
    回顾性,150例患者的177只眼的介入病例系列,与埃塞俄比亚邦德(约翰逊和约翰逊,美国),在LV普拉萨德眼科研究所,海得拉巴,印度,2016年1月至2022年2月。评估患者的慢性继发性吊带感染,定义为术后6周以上发生的感染/缝线肉芽肿。所有患者术后均口服抗生素。临床资料,微生物评价,抗生素敏感性模式,并对管理结果进行了分析。
    在13例患者的14只眼(7.9%)中发现了埃塞俄比亚邦德吊带悬吊后的延迟感染。其中,8例(61.5%)为女性。从手术到就诊的平均时间间隔为7.5个月(范围:2.5个月至2.5年)。11只眼睛接受了吊带摘除。在接受初始抗生素疗程的三个人中,两个最终需要拆除吊带。7只眼睛(50%)可进行微生物学评估,以金黄色葡萄球菌为最常见的生物。在六种积极文化中,5例(83.3%)对氟喹诺酮类药物(FQs)耐药。
    用埃塞俄比亚邦德悬吊术的延迟感染发生率为8%,以金黄色葡萄球菌为最常见的生物。作者建议所有感染患者早期去除吊带,并建议在将来进行翻修手术时考虑使用替代材料。
    UNASSIGNED: To describe the incidence and management of delayed infections following frontalis sling suspension with polybutylate-coated polyester suture (Ethibond).
    UNASSIGNED: Retrospective, interventional case series of 177 eyes of 150 patients, who underwent frontalis suspension surgery with Ethibond (Johnson and Johnson, USA), at L V Prasad Eye Institute, Hyderabad, India, between January 2016 and February 2022. Patients were assessed for chronic secondary sling infection, defined as infection/suture granuloma occurring beyond 6 weeks post-surgery. All patients received postoperative oral antibiotics. The clinical profile, microbiological evaluation, antibiotic sensitivity patterns, and management outcomes were analyzed.
    UNASSIGNED: Delayed infection following Ethibond sling suspension was noted in 14 eyes of 13 patients (7.9%). Of these, eight cases (61.5%) were females. The average time interval from surgery to presentation was 7.5 months (range: 2.5 months to 2.5 years). Eleven eyes underwent sling removal. Of the three who received initial antibiotic course, two eventually needed sling removal. Microbiological evaluation was available in seven eyes (50%), with Staphylococcus aureus as the most common organism. Of the six positive cultures, five (83.3%) were resistant to fluoroquinolones (FQs).
    UNASSIGNED: Frontalis suspension with Ethibond has an 8% incidence of delayed infections, with Staphylococcus aureus as the most common organism. The authors recommend early sling removal in all patients with infection and recommend consideration of an alternative material in the event of future revision surgery.
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  • 文章类型: Journal Article
    背景:ChatGPT是由OpenAI在2022年末开发和发布的免费人工智能(AI)语言模型。这项研究旨在评估ChatGPT的性能,以准确回答2022年由美国整形外科医师协会(ASPS)发布的《眼睑下垂管理指南》中的临床问题(CQ)。
    方法:指南中的CQs被用作英语和日语的问题来源。对于每个问题,ChatGPT为CQ提供了答案,证据质量,推荐力度,引用匹配,回答单词数。我们比较了英语和日语查询中每个组件中ChatGPT的性能。
    结果:最终分析共包含11个问题,ChatGPT正确回答了61.3%的问题。与CQ的日语答案相比,ChatGPT在CQ的英语答案中具有更高的准确率(76.4%对46.4%;p=0.004)和字数(123个单词对35.9个单词;p=0.004)。证据质量无统计学差异,推荐力度,和参考匹配。总共提出了697个参考文献,但其中只有216个(31.0%)存在。
    结论:ChatGPT显示出作为治疗上睑下垂的辅助工具的潜力。然而,重要的是要认识到现有的人工智能模型有明显的局限性,其主要作用应该是补充医疗专业人员的专业知识。
    方法:在受尊重的权威下进行观察性研究。该期刊要求作者为每篇文章分配一定程度的证据。对于这些循证医学评级的完整描述,请参阅目录或在线作者说明www。springer.com/00266.
    BACKGROUND: ChatGPT is a free artificial intelligence (AI) language model developed and released by OpenAI in late 2022. This study aimed to evaluate the performance of ChatGPT to accurately answer clinical questions (CQs) on the Guideline for the Management of Blepharoptosis published by the American Society of Plastic Surgeons (ASPS) in 2022.
    METHODS: CQs in the guideline were used as question sources in both English and Japanese. For each question, ChatGPT provided answers for CQs, evidence quality, recommendation strength, reference match, and answered word counts. We compared the performance of ChatGPT in each component between English and Japanese queries.
    RESULTS: A total of 11 questions were included in the final analysis, and ChatGPT answered 61.3% of these correctly. ChatGPT demonstrated a higher accuracy rate in English answers for CQs compared to Japanese answers for CQs (76.4% versus 46.4%; p = 0.004) and word counts (123 words versus 35.9 words; p = 0.004). No statistical differences were noted for evidence quality, recommendation strength, and reference match. A total of 697 references were proposed, but only 216 of them (31.0%) existed.
    CONCLUSIONS: ChatGPT demonstrates potential as an adjunctive tool in the management of blepharoptosis. However, it is crucial to recognize that the existing AI model has distinct limitations, and its primary role should be to complement the expertise of medical professionals.
    METHODS: Observational study under respected authorities. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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