■生物粘附是材料粘附到生物表面的能力。生物粘合剂是诱导或促进生物粘附的物质。近年来,生物粘合剂的内部应用越来越受欢迎,并且越来越多地用于玻璃体视网膜手术。这篇综述的目的是讨论各种生物粘合剂及其在玻璃体视网膜手术中的应用。
■PubMed,谷歌学者,使用ePub和Cochrane库数据库进行文献选择。关键词如玻璃体视网膜手术,生物粘合剂,眼内生物粘合剂,胶水,纤维蛋白胶,分别使用氰基丙烯酸酯胶和转化生长因子,并以不同的组合进行全面的系统文献检索。
■共检索到47篇论文,并纳入这篇综述。1976年,氰基丙烯酸酯胶是第一种用于人眼玻璃体视网膜手术的生物粘合剂。使用生物粘附剂的最常见适应症是视盘凹陷黄斑病变,黄斑裂孔和孔源性视网膜脱离。
■在玻璃体视网膜手术中使用眼内生物粘附剂代表了眼科研究中重要且不断发展的兴趣领域。虽然率先使用氰基丙烯酸酯胶,纤维蛋白胶和转化生长因子β证明了眼内粘合剂的可能用途,纤维蛋白胶是玻璃体视网膜手术中使用最广泛的眼内生物粘合剂。
UNASSIGNED: Bioadhesion is the ability of materials to adhere to biological surfaces.
Bioadhesives are substances which induce or promote bioadhesion. The internal application of
bioadhesives is gaining popularity in recent years and is being increasingly utilized in vitreoretinal surgeries. The aim of this review is to discuss the various
bioadhesives and their applications in vitreoretinal surgeries.
UNASSIGNED: PubMed, Google Scholar, ePub and Cochrane library database were used for literature selection. Keywords such as vitreoretinal surgery,
bioadhesives, intraocular
bioadhesives, glue, fibrin glue, cyanoacrylate glue and transforming growth factor were used individually and in differing combinations to perform a comprehensive systematic literature search.
UNASSIGNED: A total of 47 papers were retrieved and included in this review. Cyanoacrylate glue was the first bioadhesive to be utilized for vitreoretinal surgery in human eyes in 1976. The most common indications for the use of
bioadhesives were in optic disc pit maculopathy, macular holes and rhegmatogenous retinal detachments.
UNASSIGNED: The use of intraocular bioadhesives in vitreoretinal surgery represents a significant and evolving area of interest within ophthalmic research. While the pioneering use of cyanoacrylate glue, fibrin glue and transforming growth factor beta demonstrated the possible use of intraocular adhesives, fibrin glue is the most widely used intraocular bioadhesive in vitreoretinal surgery.