未经评估:结核病是艾滋病毒感染者的主要传染病之一。因此,这项研究的目的是调查在阿姆哈拉地区政府医院接受治疗的HIV阳性成人中影响结核病发展的因素,埃塞俄比亚。
UNASSIGNED:一项以医院为基础的回顾性研究设计,在阿姆哈拉地区17家政府医院的700名接受HAART治疗的HIV阳性成人中进行,埃塞俄比亚。
未经证实:患者的年龄(AOR=1.122,95%CI:1.013,2.234),基线CD4细胞计数(AOR=0.888,95%CI:0.714,0.945),没有伴侣的患者(AOR=1.212,95%CI:1.051,1.123),接受治疗的女性(AOR=0.786,95%CI;0.564,0.845),非机会性疾病(AOR=0.865,95%CI:0.731,0.938),患者未披露其HIV状况(AOR=1.241,95%CI:1.087,2.341),农村患者(AOR=1.135,95%CI:1.032,1.353,未受过教育的患者(AOR=1.125,95%CI:1.056,1.546),低依从性患者(AOR=1.225,95%CI:1.191,2.453),卧床不起的患者(AOR=1.223,95%CI:1.131,1.521),非卧床患者(AOR=1.156,95%CI:1.091,1.267),非吸烟者患者(AOR=0.854,95%CI:0.686,0.935)显着影响感兴趣的变量。同样,酒精摄入量,药物毒性和WHO基线临床分期显著影响了接受治疗的HIV阳性患者的结核病发展。
未经批准:在这项研究中,基线CD4细胞计数,女性患者,非机会性疾病,非吸烟状况与结核病的发展呈负相关,而患者的年龄,没有伴侣的生活,没有受过教育的病人,依从性低的患者,卧床和非卧床患者与HIV患者的结核病发展呈正相关。这项研究中获得的发现对服务提供者和患者都很重要。应更多地注意那些与响应变量呈正相关的变量。地区卫生局应在每家医院开设结核病/艾滋病毒合并感染小节,例如ART小节。
UNASSIGNED: Tuberculosis is one of the leading infectious diseases for people living with HIV. Therefore, the purpose of this study was to investigate factors affecting the development of TB among HIV-positive adults under treatment in government hospitals of Amhara Region, Ethiopia.
UNASSIGNED: A hospital-based retrospective study design was conducted among 700 HIV-positive adults under HAART in 17 government hospitals in the Amhara region, Ethiopia.
UNASSIGNED: Age of the patients (AOR = 1.122, 95% CI:1.013, 2.234), baseline CD4 cell count (AOR = 0.888, 95% CI: 0.714, 0.945), patients living without their partner (AOR = 1.212, 95% CI: 1.051, 1.123), females under treatment (AOR = 0.786, 95% CI; 0.564, 0.845), non-opportunistic diseases (AOR = 0.865, 95% CI: 0.731, 0.938), patients not disclosed their HIV status (AOR = 1.241, 95% CI: 1.087, 2.341), rural patients (AOR = 1.135, 95% CI: 1.032, 1.453, patient with no education (AOR = 1.125, 95% CI: 1.056, 1.546), low adherence patients (AOR = 1.225, 95% CI: 1.191, 2.453), bedridden patients (AOR = 1.223, 95% CI: 1.131, 1.521), ambulatory patients (AOR = 1.156, 95% CI:1.091, 1.267), non-smoker patients (AOR = 0.854, 95% CI: 0.686, 0.935) significantly affected on the variable of interest. Similarly, alcohol intake, drug toxicity and baseline clinical WHO stages significantly affected for the development of tuberculosis in HIV-positive patients under treatment.
UNASSIGNED: In this study, baseline CD4 cell count, female patients, non-opportunistic diseases, and non-smoking status were negatively associated with the development of TB, whereas age of patients, living without partners, patients with no education, patients with low adherence, bedridden and ambulatory patients were positively associated to the development of TB in HIV patients. The findings obtained in this study are important for both service providers and patients. More attention should be given to those positively associated variables to response variables. The regional health bureau should open TB/HIV co-infection subsections like ART sections in each hospital.