背景：肝外胆管非霍奇金淋巴瘤（EBNHL）很少见，胆道恶性肿瘤的患病率为0.6%。原发性胆道非霍奇金淋巴瘤占结外非霍奇金淋巴瘤（NHL）的0.4%，约占所有NHL病例的0.016%。患者表现为典型的胆管消失综合征。后期表现是嗜血综合征。
方法：该患者因间歇性发热入院，腹痛19天。”相关实验室检查显示严重感染。患者根据腹腔感染进行治疗,然后进行腹腔镜胆囊切除术。手术后,患者的病情没有缓解，进一步恶化。术后患者表现不是基于术前估计，并且手术没有达到预期的效果。术后病理诊断为胆囊非霍奇金淋巴瘤。患者最终死亡。
结论：非结石性炎症更常见于胆囊。非结石感染一般是由胆汁淤滞和缺血引起的,导致细菌繁殖和血液供应减少，坏疽和胆囊穿孔更容易发生。该患者也根据该想法进行诊断和治疗。手术后的发展完全超出了我们的预期。胆囊非霍奇金淋巴瘤非常罕见,这个病例还包括噬血细胞综合征和胆管消失综合征,这是罕见的。
结论：肝外胆道系统恶性淋巴瘤极为罕见，临床表现易误诊。同时,非结石性胆囊炎伴发热，应考虑黄疸和肝脾肿大。
BACKGROUND: Extrahepatic biliary non-Hodgkin\'s lymphoma (EBNHL) is rare, with a prevalence of 0.6% of malignant biliary tumors. Primary biliary non-Hodgkin\'s lymphoma accounts for 0.4% of extranodal non-Hodgkin\'s lymphoma (NHL), accounting for approximately 0.016% of all NHL cases. The patient presented with typical bile duct disappearance syndrome. The late performance is a bloodthirsty syndrome.
METHODS: This patient was admitted to the hospital with \"intermittent fever, abdominal pain for 19 days\". The relevant laboratory tests showed severe infection. The patients were treated according to abdominal infection, and then laparoscopic cholecystectomy was performed. After the operation, the patient\'s condition did not relieve and further deteriorated. Postoperative patient performance was not based on preoperative estimates, and surgery did not achieve the desired results. Postoperative pathological diagnosis confirmed gallbladder non-Hodgkin\'s lymphoma. The patient eventually died.
CONCLUSIONS: Non-calculus inflammation occurs more frequently in the gallbladder. Non-calculus infections are generally caused by bile stasis and ischemia, resulting in bacterial reproduction and reduced blood supply, and gangrene and perforation of the gallbladder are more likely to occur. This patient is also diagnosed and treated according to this idea. The development after surgery completely exceeded our expectations. Gallbladder non-Hodgkin\'s lymphoma is very rare, and this case also includes hemophagocytic syndrome and bile duct disappearance syndrome, which is rare.
CONCLUSIONS: Malignant lymphoma of the extrahepatic biliary system is extremely rare, and its clinical manifestations are easily misdiagnosed. At the same time, non-calculous cholecystitis with fever, jaundice and hepatosplenomegaly should be considered.
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