Bilateral calcifications

  • 文章类型: Case Reports
    我们提出了一个病例报告硬化脉络膜钙化(SCC),在一名70岁的患者中,这是一种罕见的疾病,涉及焦磷酸钙沉积在眼后极。我们介绍了临床表现及其在多模态图像中的外观,使用彩色眼底摄影,扫频源光学相干层析成像(SS-OCT),眼超声,和新颖的后向模式成像(RMI)技术。右眼(OD)视力为20/25,左眼(OS)视力为20/20。彩色眼底照相显示,两只眼睛的上颞区都有淡黄色的沉积物。SS-OCT显示巩膜源性肿块。眼部超声证实了这些肿块的钙化。RMI检测到具有明显表面高度的高反射图像。系统实验室检查结果未发现任何异常,导致双侧特发性SCC的诊断。
    We present a case report on sclerochoroidal calcification (SCC), a rare condition involving calcium pyrophosphate deposits in the posterior pole of the eye in a 70-year-old patient. We provide an account of the clinical presentation and its appearance in multimodal images, using color fundus photography, swept-source optical coherence tomography (SS-OCT), ocular ultrasound, and the novel retro-mode imaging (RMI) technique. Visual acuity was 20/25 in the right eye (OD) and 20/20 in the left eye (OS). Color fundus photography revealed yellowish deposits located in the upper temporal arcade of both eyes. SS-OCT demonstrated masses of scleral origin. Ocular ultrasounds confirmed the calcification of these masses. RMI detected hyper-reflective images with marked superficial elevation. Systemic laboratory results did not detect any abnormalities, leading to the diagnosis of bilateral idiopathic SCC.
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  • 文章类型: Case Reports
    背景:由于巩膜和脉络膜中钙和磷酸盐的沉积,硬化脉络膜钙化是一种罕见的与老年斑相对应的疾病。这是一个老年患者的病理。在大多数情况下,它是特发性的。然而,一些患者患有系统性疾病,导致磷酸盐代谢紊乱,这是这种疾病的根源。因此需要检查以检测它们。
    方法:我们报告了一例65岁的患者,该患者入院眼科进行光学矫正。已知患者在服用抗炎药后患有关节软骨钙质沉着症。眼底检查显示双眼有多个白色黄斑上脉络膜病变,呈肿瘤样外观。超声检查显示病变的钙化性质。荧光素和吲哚菁绿血管造影没有显示新血管活动或存在的迹象。一个完整的代谢检查,主要是磷钙,再次订购,并保留了关节软骨钙质沉着症的全身诊断。
    结论:Shields等人。首先描述,1997年,一名患有软骨钙质沉着症和正常代谢特征的患者出现硬化脉络膜钙化。很少有更多的文献被添加到文献中。通常认为主要是双侧的,最常视为淡黄色病变。迄今为止,已经描述了两种类型的钙化,斑块类型和假瘤类型。鉴于无症状的表现,软骨钙质沉着症患者应进行眼底检查。一般来说,不需要治疗。
    结论:在无症状的老年患者中,脉络膜钙化通常表现为多发性离散黄色胎盘病变。硬化脉络膜分类的视觉预后良好,因为病变倾向于远离黄斑。不应将其与需要更广泛治疗的脉络膜转移或无色黑色素瘤相混淆。
    BACKGROUND: Sclerochoroidal calcifications is a rare condition corresponding to senile plaques due to the deposition of calcium and phosphate in the sclera and choroid. It is an elderly patient\'s pathology. In most cases, it is idiopathic. However, some patients have systemic disorders leading to disturbances in phosphocalcic metabolism, which are at the origin of this disorder. A check-up is therefore necessary to detect them.
    METHODS: We report the case of a 65 year old patient admitted to the ophthalmology department for a renewal of optical correction. The patient is known to have articular chondrocalcinosis on anti-inflammatory medication. Fundus examination revealed multiple white supra macular choroidal lesions with tumour-like appearance in both eyes. The ultrasound perfomed showed the calcic nature of the lesions. Fluorescein and indocyanine green angiograms showed no sign of activity or presence of neovessels.A complete metabolic work-up, mainly phosphocalcic, was ordered again and the systemic diagnosis of articular chondrocalcinosis was retained.
    CONCLUSIONS: Shields et al. first described, in 1997, a case of sclerochoroidal calcification in a patient with chondrocalcinosis and a normal metabolic profile. Few more have been added to the literature. It is generally considered to be predominantly bilateral and is most often seen as yellowish lesions. Two types of calcifications have been described to date, the plaque type and the pseudotumor type. Given the asymptomatic presentation, a fundus examination should be performed in patients with chondrocalcinosis. Generally, no treatment is necessary.
    CONCLUSIONS: Sclerochoroidal calcifications usually manifests as multiple discrete yellow placoid lesions in elderly asymptomatic patients. Visual prognosis for sclerochoroidal classification is good since the lesions tend to be away from the macula. They should not be confused with choroidal metastasis or achromic melanoma which require more extensive treatment.
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  • 文章类型: Case Reports
    BACKGROUND: Sclerochoroidal calcification (SCC) is a rare and benign condition found mostly in middle-aged and elderly Caucasian men, characterized by multiple yellow-white lesions seen most commonly in the temporal regions of the fundus. While they may be concerning for benign tumors, primary neoplasias or metastases, SCCs most commonly present as asymptomatic findings during routine ophthalmologic testing and have a very good prognosis as they rarely cause visual deficits.
    OBJECTIVE: To report and describe the findings in a case of bilateral idiopathic sclerochoroidal calcifications.
    METHODS: A retrospective case report.
    RESULTS: Repeated ophthalmological exams, including fundoscopic examination, ultrasonography, optical coherence tomography and fluorescein angiography, were all consistent bilateral idiopathic sclerochoroidal calcifications.
    CONCLUSIONS: While most cases of idiopathic sclerochoroidal calcifications represent a benign ophthalmological condition, there are known associations with other systemic conditions, such as hyperthyroidism, hyperparathyroidism, Bartter\'s syndrome and Gitelman\'s syndrome. It is for this reason that these patients warrant a full systemic work-up in addition to careful ophthalmological monitoring.
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