Best practices

最佳做法
  • 文章类型: Editorial
    用于研究的医学图像的去识别是数据共享计划的核心要求,特别是随着人工智能(AI)应用程序对数据的需求增长。美国国家癌症研究所(NCI)的生物医学信息学和信息技术中心(CBIIT)召开了一个虚拟研讨会,旨在总结去识别技术和过程的最新技术,并探索该主题的有趣方面。本文总结了研讨会第一天的亮点,录音,以及可公开查阅的介绍。涵盖的主题包括医学影像去识别倡议(MIDI)工作组关于最佳实践和建议的报告,传统方法去识别的工具,去身份识别的国际方法,和一个行业小组。
    De-identification of medical images intended for research is a core requirement for data-sharing initiatives, particularly as the demand for data for artificial intelligence (AI) applications grows. The Center for Biomedical Informatics and Information Technology (CBIIT) of the US National Cancer Institute (NCI) convened a virtual workshop with the intent of summarizing the state of the art in de-identification technology and processes and exploring interesting aspects of the subject. This paper summarizes the highlights of the first day of the workshop, the recordings, and presentations of which are publicly available for review. The topics covered included the report of the Medical Image De-Identification Initiative (MIDI) Task Group on best practices and recommendations, tools for conventional approaches to de-identification, international approaches to de-identification, and an industry panel.
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  • 文章类型: Journal Article
    2023年9月,美国食品和药物管理局(FDA)发布了指南草案,以就如何获得伴侣动物临床试验的知情客户同意发表评论。本指南有可能大幅改变兽医社区知情同意书的编写和提交给客户的方式。它不仅提供了有关如何获得所有者的知情同意的细节,而且还提供了应获得同意的时间表,同意书中的格式和语言,以及这些同意书中所需要素的详细信息。这些变化将涉及调查人员的额外努力,以确保合规性,但可能导致所有者依从性增加,并增加临床研究的入学率,并为所有人带来后续益处。
    In September 2023 the United States Food and Drug Administration (FDA) released draft guidance for comment about how informed client consent for companion animal clinical trials should be obtained. This guidance has the potential to substantially change how informed consent documents are written and presented to clients in the veterinary community. It provides specifics not only about how to obtain informed consent from owners but also the timeframe within which consent should be obtained, the formatting and language in the consent forms, and details on elements that are required to be in these consent forms. These changes will involve additional efforts by investigators to ensure compliance yet might lead to increased owner compliance and higher enrollment in clinical studies with subsequent benefits for all.
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  • 文章类型: Journal Article
    物质使用与亲密伴侣暴力(IPV)密切相关,并且是IPV的可修改风险因素。然而,缺乏对同时发生的IPV和物质使用的全面筛查和转诊,以及他们的精神后遗症,限制了与物质相关的IPV的有效干预措施的识别和实施。这篇叙述性综述(1)调查了IPV筛查和转诊实践的文献,如果这些包括筛查物质使用或其他精神病合并症,(2)为当前的最佳实践提供建议,(3)提出了旨在识别和减少与物质相关的IPV的研究和实践的未来方向。
    一篇叙述性文献综述审查了在诊所中调查IPV筛查和转诊计划的研究。部分研究进行了回顾:(1)有效性,(2)实施和可持续性的障碍,和(3)对精神病共病的反应,包括物质使用和物质使用障碍(SUD)。
    研究结果表明,已经制定了有效的IPV筛查和转诊计划,但是IPV筛查存在差异,许多程序仅筛查IPV受害情况。IPV筛查计划的实施和可持续性的障碍包括缺乏持续的提供者培训,资金或机构支持,并直接连接到转介服务。Further,许多IPV筛查计划缺乏共患精神病的评估和转诊,包括物质使用,并且往往不在SUD诊所常规实施。
    需要开展额外的系统性工作,以制定与物质相关的IPV的普遍和全面的筛查和转诊计划,并解决长期可持续性问题。特别是在SUD治疗设置内。
    UNASSIGNED: Substance use is strongly associated with intimate partner violence (IPV) and is a modifiable risk factor for IPV. However, lack of comprehensive screening and referral for co-occurring IPV and substance use, along with their psychiatric sequalae, limits the identification and implementation of effective interventions for substance-related IPV. This narrative review (1) investigates the literature on screening and referral practices for IPV, and if these include screening for substance use or other psychiatric comorbidities, (2) provides recommendations for current best practices, and (3) suggests future directions for research and practice aimed at identifying and reducing substance-related IPV.
    UNASSIGNED: A narrative literature review examined studies investigating IPV screening and referral programs in clinics. Selected studies were reviewed for: (1) effectiveness, (2) barriers to implementation and sustainability, and (3) responsivity to psychiatric comorbidity, including substance use and substance use disorders (SUD).
    UNASSIGNED: Findings suggest that effective IPV screening and referral programs have been developed, but disparities in IPV screening exist and many programs only screen for IPV victimization. Barriers to the implementation and sustainability of IPV screening programs include lack of ongoing provider training, funding or institutional support, and direct connection to referral services. Further, many IPV screening programs lack assessment of and referral for comorbid psychiatric conditions, including substance use, and tend not to be routinely implemented in SUD clinics.
    UNASSIGNED: Additional systematic work is needed to develop universal and comprehensive screening and referral programs for substance-related IPV and address issues of long-term sustainability, particularly within SUD treatment settings.
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  • 文章类型: Journal Article
    背景:尊重生育储备,正如世界卫生组织在2018年所强调的那样,以及对积极需求的关注,有尊严的分娩体验已成为尊重产妇护理(RMC)的一个组成部分。众所周知,RMC对于良好的分娩结果至关重要,并有助于提高产妇护理的满意度。缺乏RMC会对妇女和新生儿的权利产生负面影响。该研究旨在探索医疗保健提供者对母亲先前报道的维持RMC行动的看法。
    方法:这项研究是在东部卢旺达省的五家医院进行的,涉及与助产士和护士的5次焦点小组讨论(FGD)。对于采访,我们有目的地选择了5个部门的经理和5名医生.此外,FGD招募了40名助产士和护士。这项研究利用了欣赏调查(AI)的梦想阶段进行访谈和焦点小组。数据收集旨在深入了解医疗保健提供者对如何提供RMC以及如何在卢旺达医疗机构中建立和维持RMC的看法。Nvivo12用于组织代码并创建码本,并应用了专题分析。
    结果:出现了四个带有子主题的主题。即,1)以妇女为中心的护理,在同情的关怀下,隐私和保密维护,决策中的信息提供和自由,有效沟通,家庭参与,清洁度,平等关怀。2)对激励员工的专业遵守,团队合作,持续发展,质量工作规定,社区信任。3)RMC遇到4)RMC寄托。
    结论:卢旺达不断追求高RMC标准涉及通过利用现有资源改善分娩体验,持续改进,和持续的成就。本研究中关于维持RMC的主要建议行动包括促进以妇女为中心的护理,加强医疗保健提供者的态度,确保专业性,建立社区信任,维持有利的卫生设施环境,涉及领导。
    BACKGROUND: Childbirth reserves respect, as emphasized by the World Health Organization in 2018, and the focus towards the need for positive, dignified delivery experiences has become an integral aspect of Respectful Maternity Care (RMC). It is a known fact that RMC is pivotal for favourable birth outcomes and contributes to the satisfaction of maternity care. The absence of RMC negatively affects women\'s and newborns\' rights. The study aimed to explore healthcare providers\' perspectives on sustaining RMC actions that mothers previously reported.
    METHODS: This study was conducted in five hospitals in the Eastern province of Rwanda, involving 5 Focus Group Discussions (FGDs) with midwives and nurses. For interviews, we purposively selected 5-unit managers and five physicians. Additionally, 40 midwives and nurses were recruited for the FGDs. The research utilized the Dream phase of Appreciative Inquiry (AI) for interviews and Focus Groups. Data collection aimed to gain insights into Healthcare Providers\' perceptions of how RMC is provided and how to establish and sustain RMC in Rwandan health facilities. Nvivo 12 was employed for organizing codes and creating a codebook, and thematic analysis was applied.
    RESULTS: Four themes with sub-themes emerged. Namely, 1) Women-centered care, with Compassionate care, Privacy and confidentiality maintenance, Information provision and Liberty in decision making, Effective communication, Family involvement, Cleanliness, and Equality care. 2) Professionalism compliance with Motivated staff, Teamwork, Continuous development, Quality work provision, and Community trust. 3) RMC encounters 4) RMC sustenance.
    CONCLUSIONS: The continuous pursuit of high RMC standards in Rwanda involves improving childbirth experiences through utilizing existing resources, ongoing improvement, and sustaining achievements. Key recommended actions in this study for sustaining RMC encompass promoting women-centred care, enhancing healthcare provider attitudes, ensuring professionalism, building community trust, maintaining conducive health facility environments, and involving leadership.
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  • 文章类型: Journal Article
    背景:透明度可以在科学过程中建立信任,但是科学发现可能会被不良和晦涩的数据使用和报告实践所破坏。这项工作的目的是报告迄今为止如何使用青少年大脑认知发育(ABCD)研究的数据,并就如何提高调查结果的透明度和可重复性提供切实可行的建议。
    方法:2017年至2023年发表的使用ABCD研究数据的文章使用30多个数据提取项目进行了审查,以收集有关数据使用实践的信息。报告了每个提取项目的总频率,以及表示提取项目总体认可的完整性水平(LOC)分数的计算。使用单变量线性回归模型来检查LOC评分与单个提取项目之间的相关性。事后分析包括检查LOC得分是否与记录的2年期刊影响因子相关。
    结果:主要分析中包含549篇全长文章。分析脚本在30%的完整文章中共享。60%的文章报告了因数据缺失而被排除在外的参与者数量,以及单个变量缺失数据的信息(例如,家庭收入)在38%的文章中提供。83%的文章中包含了描述分析样本的表格。78%的评论文章中包括种族和/或种族变量,而其中只有41%的文章是合理的。LOC评分与缺失数据检查相关的提取项目高度相关。与LOC得分的前10%相比,LOC得分的后10%与较低的日志影响因子显著相关(β=-0.77,95%-1.02,-0.51;p值<0.0001)。
    结论:这些发现强调了在未来的论文中改进的机会,这些论文使用ABCD研究数据来轻松调整分析实践,以实现更好的透明度和可重复性。提供了一系列建议,以促进未来研究的坚持。
    BACKGROUND: Transparency can build trust in the scientific process, but scientific findings can be undermined by poor and obscure data use and reporting practices. The purpose of this work is to report how data from the Adolescent Brain Cognitive Development (ABCD) Study has been used to date, and to provide practical recommendations on how to improve the transparency and reproducibility of findings.
    METHODS: Articles published from 2017 to 2023 that used ABCD Study data were reviewed using more than 30 data extraction items to gather information on data use practices. Total frequencies were reported for each extraction item, along with computation of a Level of Completeness (LOC) score that represented overall endorsement of extraction items. Univariate linear regression models were used to examine the correlation between LOC scores and individual extraction items. Post hoc analysis included examination of whether LOC scores were correlated with the logged 2-year journal impact factor.
    RESULTS: There were 549 full-length articles included in the main analysis. Analytic scripts were shared in 30 % of full-length articles. The number of participants excluded due to missing data was reported in 60 % of articles, and information on missing data for individual variables (e.g., household income) was provided in 38 % of articles. A table describing the analytic sample was included in 83 % of articles. A race and/or ethnicity variable was included in 78 % of reviewed articles, while its inclusion was justified in only 41 % of these articles. LOC scores were highly correlated with extraction items related to examination of missing data. A bottom 10 % of LOC score was significantly correlated with a lower logged journal impact factor when compared to the top 10 % of LOC scores (β=-0.77, 95 % -1.02, -0.51; p-value < 0.0001).
    CONCLUSIONS: These findings highlight opportunities for improvement in future papers using ABCD Study data to readily adapt analytic practices for better transparency and reproducibility efforts. A list of recommendations is provided to facilitate adherence in future research.
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  • 文章类型: Journal Article
    背景:自COVID-19大流行以来,远程医疗保健现在是主流医疗保健的关键要素,所有类型的医疗保健提供者都加入了数字革命。作为一个经历医疗保健差距的人口,有发育障碍的成年人及其支持者描述了远程医疗保健的不同经历,这些经历有助于整体护理质量和健康结果.方法:这项e-Delphi研究就美国发育障碍成年人的远程医疗保健最佳实践达成了共识。对44名具有远程保健和发育障碍经验的专家小组成员进行了在线调查和视频会议访谈,包括有发育障碍的成年人,家庭成员,直接支持专业人员,护士,和医疗保健提供者。结果:三轮调查得出了9个指南,包括42个项目。准则解决了1)远程医疗保健的适当情况,2)沟通需求和偏好,3)支持人员协作,4)教育和预期指导,5)提醒,6)协调护理,7)公平和公正的准入,8)隐私和安全,和9)循证实践。结论:医疗保健提供者可以采用这些最佳实践指南,以确保向有发育障碍的成年人公平安全地提供远程医疗保健。需要进行政策宣传,以采纳这些准则,并使卫生保健提供者和有发育障碍的成年人获得安全有效地使用远程卫生保健所需的资源。
    Background: Telehealth care is now a key element of mainstream health care since the COVID-19 pandemic, with all types of health care providers joining the digital revolution. As a population experiencing health care disparities, adults with developmental disabilities and their supporters have described variable experiences with telehealth care that contribute to overall care quality and health outcomes. Methods: This e-Delphi study established consensus on best practices in telehealth care for adults with developmental disabilities in the United States. Online surveys and videoconferencing interviews were conducted with 44 expert panelists with experience with telehealth care and developmental disabilities, including adults with developmental disabilities, family members, direct support professionals, nurses, and health care providers. Results: Three rounds of surveys resulted in a set of 9 guidelines consisting of 42 items. The guidelines addressed 1) appropriate situations for telehealth care, 2) communication needs and preferences, 3) support person collaboration, 4) education and anticipatory guidance, 5) reminders, 6) coordination of care, 7) equitable and fair access, 8) privacy and safety, and 9) evidence-based practice. Conclusion: Health care providers can adopt these best practice guidelines to ensure telehealth care is provided equitably and safely to adults with developmental disabilities. Policy advocacy is needed for the uptake of these guidelines and for health care providers and adults with developmental disabilities to access the resources needed for safe and effective telehealth care use.
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  • 文章类型: Journal Article
    文献中越来越多地记录了对安全气候的积极看法与医护人员行为之间的关系。负面观念的潜在影响尚未得到充分研究,尚未就标准预防措施的依从性进行专门检查。我们使用作为多站点的一部分收集的数据来解决这一差距,横断面研究,包括来自43个医疗外科医院单位的452名护士的回应。这份简短的报告描述了对患者安全气候的负面看法与医院护士的标准预防措施依从性之间的关联。
    The relationships among positive perceptions of safety climate and better healthcare worker behaviors have been increasingly documented in the literature. The potential influence of negative perceptions is underexplored and has not been examined in relationship to infection prevention practices. We begin to address this gap using data collected as part of a multi-site, cross-sectional study. This brief report describes associations identified between negative perceptions of patient safety climate and standard precaution adherence of hospital-based nurses.
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  • 文章类型: Journal Article
    背景:国际神经调节学会(INS)已经认识到有必要建立最佳实践,以优化可植入设备并在未实现理想结果时进行救助。该小组成立了神经刺激适当性共识委员会(NACC)®,为我们的成员和受神经调节设备影响的更广泛的社区所需的事项提供指导。
    方法:INS执行委员会根据专业知识提名了该NACC®出版物的教师,出版物,和职业工作在这个问题上。此外,选择教师是考虑到多样性和不同的职业道路和人口类别的包容性。一旦被选中,教师被要求对当前证据进行评分,并与专家意见一起制定共识建议,以解决有关该主题的信息中的失误。
    结果:NACC®小组为使用留置装置的患者提供了有关抢救和优化护理的信息和权威建议。这些建议基于证据和专家意见,随着每个主题的新数据生成,预计将不断发展。
    结论:NACC®指导应考虑植入刺激装置治疗慢性疼痛的任何患者。应考虑这些共识点,以在外植体之前挽救可能发生故障的设备。
    BACKGROUND: The International Neuromodulation Society (INS) has recognized a need to establish best practices for optimizing implantable devices and salvage when ideal outcomes are not realized. This group has established the Neurostimulation Appropriateness Consensus Committee (NACC)® to offer guidance on matters needed for both our members and the broader community of those affected by neuromodulation devices.
    METHODS: The executive committee of the INS nominated faculty for this NACC® publication on the basis of expertise, publications, and career work on the issue. In addition, the faculty was chosen in consideration of diversity and inclusion of different career paths and demographic categories. Once chosen, the faculty was asked to grade current evidence and along with expert opinion create consensus recommendations to address the lapses in information on this topic.
    RESULTS: The NACC® group established informative and authoritative recommendations on the salvage and optimization of care for those with indwelling devices. The recommendations are based on evidence and expert opinion and will be expected to evolve as new data are generated for each topic.
    CONCLUSIONS: NACC® guidance should be considered for any patient with less-than-optimal outcomes with a stimulation device implanted for treating chronic pain. Consideration should be given to these consensus points to salvage a potentially failed device before explant.
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  • 文章类型: Journal Article
    背景:国际神经调节学会召集了一个基于专业知识和国际代表的多专业医师小组,以建立缓解神经调节并发症的循证指导。该神经刺激适当性共识委员会(NACC)®项目旨在更新循证指南,并提供专家意见,以提高疗效和安全性。
    方法:根据作者的临床专业知识选择作者,熟悉同行评审的文献,研究生产力,以及对神经调节文献的贡献。科领导监督MEDLINE的文献检索,BioMedCentral,当前内容连接,Embase,国际医药文摘,WebofScience,谷歌学者,和PubMed从2017年(NACC上次发布指南时)到2023年10月。使用美国预防服务工作组标准对确定的研究进行了分级,以证明净收益的证据和确定性。建议基于证据的强度或证据不足时的共识。
    结果:NACC审查了已发表的文献,并建立了基于证据和共识的建议,以指导最佳实践。在此过程的未来迭代中,随着新证据的发展,将出现其他指导。
    结论:NACC推荐关于缓解与神经刺激相关的并发症的最佳实践,以提高安全性和疗效。基于证据和共识的建议应用作指导,以在临床上适当时协助决策。
    BACKGROUND: The International Neuromodulation Society convened a multispecialty group of physicians based on expertise and international representation to establish evidence-based guidance on the mitigation of neuromodulation complications. This Neurostimulation Appropriateness Consensus Committee (NACC)® project intends to update evidence-based guidance and offer expert opinion that will improve efficacy and safety.
    METHODS: Authors were chosen on the basis of their clinical expertise, familiarity with the peer-reviewed literature, research productivity, and contributions to the neuromodulation literature. Section leaders supervised literature searches of MEDLINE, BioMed Central, Current Contents Connect, Embase, International Pharmaceutical Abstracts, Web of Science, Google Scholar, and PubMed from 2017 (when NACC last published guidelines) to October 2023. Identified studies were graded using the United States Preventive Services Task Force criteria for evidence and certainty of net benefit. Recommendations are based on the strength of evidence or consensus when evidence was scant.
    RESULTS: The NACC examined the published literature and established evidence- and consensus-based recommendations to guide best practices. Additional guidance will occur as new evidence is developed in future iterations of this process.
    CONCLUSIONS: The NACC recommends best practices regarding the mitigation of complications associated with neurostimulation to improve safety and efficacy. The evidence- and consensus-based recommendations should be used as a guide to assist decision-making when clinically appropriate.
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  • 文章类型: Journal Article
    目的:躁动是一种常见的院前问题,并且经常在没有明确病因的情况下出现。鉴于院前设置的动态环境,从历史上看,严重依赖肠胃外药物治疗躁动的方法多种多样。较新的最佳实践指南建议使用口服药物来治疗躁动患者。因此,我们评估了方案发生变化后,在单一系统中口服利培酮的使用情况.方法:这是针对8个月内的城市/郊区急诊医疗服务系统进行的回顾性图表审查。包括在整个服务中实施该药物的第一天。如果它们包括利培酮口服溶解片剂(ODT)作为图表药物,则包括用于选择的图表。主要结果是给予其他药物治疗躁动。探索性结果测量包括接受药物,有记录的护理人员受伤,记录患者受伤情况,场景时间,以及可能与药物有关的不良事件。结果:共筛选552条记录纳入。利培酮被提供给530名患者,并被512名(96.6%)接受。在这512名患者中,纳入患者的中位年龄为39岁(IQR29~52岁),范围为18~89岁.9例(1.8%)需要抢救或额外的躁动药物。服用利培酮后,共有4例(0.8%)潜在并发症。本研究中没有报告院前人员随后受伤或患者受伤的袭击。结论:在大型城市和郊区EMS系统中,发现利培酮ODT是治疗轻度躁动的安全有效药物。很少需要额外的药物来治疗躁动,并且没有记录到患者或护理人员受伤。
    UNASSIGNED: Agitation is a common prehospital problem and frequently presents without a clear etiology. Given the dynamic environment of the prehospital setting, there has historically been a varied approach to treating agitation with a heavy reliance on parenteral medications. Newer best practice guidelines recommend the incorporation of oral medications to treat patients experiencing agitation. Therefore, we evaluated the use of oral risperidone in a single system after a change in protocol occurred.
    UNASSIGNED: This was conducted as a retrospective chart review of an urban/suburban Emergency Medical Services system over the period of 8 months. The first day this medication was implemented throughout the service was included. Charts were included for selection if they included risperidone oral dissolving tablet (ODT) as a charted medication. The primary outcome was administration of additional medications to treat agitation. Exploratory outcome measures included acceptance of medication, documented injury to paramedics, documented injuries to patients, scene times, and adverse events that could possibly be linked to the medication.
    UNASSIGNED: A total of 552 records were screened for inclusion. Risperidone was offered to 530 patients and accepted by 512 (96.6%). Of these 512 patients, the median age of included patients was 39 years old (IQR 29-52 years old) with a range of 18-89 years old. Rescue or additional medications for agitation were required in 9 (1.8%) cases. There were a total of 4 (0.8%) potential complications following administration of risperidone. There were no reported assaults with subsequent injuries to prehospital personnel or injuries sustained by patients reported in this study.
    UNASSIGNED: Risperidone ODT was found to be a safe and effective medication to treat mild agitation in a large urban and suburban EMS system. The need for additional medications to treat agitation was rare, and there were no documented injuries to either patients or paramedics.
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