Barrier Methods

屏障方法
  • 文章类型: Journal Article
    背景:选择避孕方法是患者的关键决定,而卫生保健专业人员(HCPs)在提供合适的建议方面面临挑战。不良的性影响往往导致不满意和停止避孕,强调在HCP和患者之间进行彻底咨询和共同决策的重要性。目的:通过对现有文献的全面回顾,探讨避孕方法与女性性功能的关系,强调在避孕处方和管理中考虑性健康的重要性。方法:对现有文献进行系统分析,结合利用有效的性健康问卷的研究,旨在阐明避孕药具与女性性功能之间的复杂相互作用。结果:该综述涵盖了各种避孕方法,包括联合激素避孕药,只含孕激素的药片,醋酸甲羟孕酮,皮下避孕植入物,荷尔蒙宫内节育器,永久灭菌,和屏障方法。从分析中收集到的见解揭示了这些方法对女性性健康的影响。结论:全面了解避孕药对女性性功能的影响对HCPs和患者都至关重要。通过将性健康考虑纳入避孕监测,合规性可以提高,避孕功效优化,并将意外怀孕的风险降至最低。这篇综述强调了定制咨询和共享决策在避孕管理中的重要性。特别是顺式女性。
    Background: Choosing a contraceptive method is a pivotal decision for patients, whereas health care professionals (HCPs) face challenges in providing suitable recommendations. Adverse sexual effects often lead to dissatisfaction and discontinuation of contraceptives, underscoring the importance of thorough counseling and shared decision making between HCPs and patients. Objective: This article aims to investigate the relationship between contraceptive methods and female sexual function through a comprehensive review of available literature, emphasizing the importance of considering sexual health in contraceptive prescription and management. Methods: A systematic analysis of existing literature, incorporating studies utilizing validated sexual health questionnaires, was conducted to elucidate the intricate interplay between contraceptives and female sexual function. Results: The review encompasses various contraceptive methods, including combined hormonal contraceptives, progestin-only pills, depot medroxyprogesterone acetate, subdermal contraceptive implants, hormonal intrauterine devices, permanent sterilization, and barrier methods. Insights gleaned from the analysis shed light on the impact of these methods on female sexual health. Conclusion: Comprehensive understanding of the effects of contraceptives on female sexual function is crucial for both HCPs and patients. By integrating sexual health considerations into contraceptive surveillance, compliance can be improved, contraceptive efficacy optimized, and the risk of unwanted pregnancies minimized. This review underscores the significance of tailored counseling and shared decision making in contraceptive management, particularly for cisgender women.
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  • 文章类型: Journal Article
    背景:在撒哈拉以南非洲地区,由于生育率持续居高不下,避孕药具的使用动态仍然是优先事项。本文重点介绍了在撒哈拉以南非洲使用屏障和使用非屏障避孕药具的情况,并假设该地区的艾滋病毒大流行将导致屏障方法的使用随着时间的推移而增加。
    方法:本文使用来自32个国家的人口与健康调查(DHS)数据,对避孕药具的使用趋势和方法组合进行了广泛分析,这些趋势涉及避孕方法在性活跃人群中的分布。本文使用交叉表格研究了避孕方法的混合动态随时间的变化以及趋势是否因婚姻状况和性别而异。它使用逻辑回归进一步检验了方法选择的决定因素。
    结果:研究结果表明,使用屏障方法,对未婚男女最明显的是,在1980年代后期至2000年代后期,该地区与艾滋病毒流行趋势同步大幅上升。结果进一步显示,不同性别的方法组合存在显着差异,男性比女性更有可能报告使用障碍方法。
    结论:研究结果表明避孕选择的偏好发生了变化。时间趋势分析强调了在这种情况下将避孕药具使用研究的重点扩大到女性以外的重要性,因为研究发现男性的趋势不同。
    BACKGROUND: Contraceptive use dynamics continue to be of priority in sub-Saharan Africa because of persistently high levels of fertility. This paper focuses on the use of barrier versus non-barrier contraceptive use in sub-Saharan Africa hypothesizing that the HIV pandemic in the region would be responsible for increases in the use of barrier methods over time.
    METHODS: This paper uses Demographic and Heath Survey (DHS) data from 32 countries to conduct extensive analysis of trends in contraceptive use and method mix that refers to the distribution of contraceptive methods use among the sexually active population. The paper examines how contraceptive method mix dynamics have changed over time and whether the trends differ by marital status and gender using cross-tabulations. It furthers examines the determinants of method choice using logistic regressions.
    RESULTS: The findings indicate that the use of barrier methods, most markedly for unmarried women and men, rose substantially between the late 1980s and late 2000s in the region in tandem with trends in HIV prevalence. The results further show marked differences in method mix by gender with men being more likely to report barrier method use than women.
    CONCLUSIONS: The findings indicate shifting preferences in contraceptive choice. The time trend analyses highlight the importance of expanding the focus of contraceptive use studies beyond women in this context as the study finds differing trends for men.
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  • 文章类型: Journal Article
    背景:尽管妇女避孕方法广泛,意外怀孕率仍然很高(美国为45%),50%导致流产。目前,全球20%的避孕药具使用是男性主导的,由于可用性有限和缺乏疗效,各国之间差异很大。全球研究表明,>50%的男性会选择使用可逆的方法,90%的女性会依靠她们的伴侣使用避孕药具。新型男性避孕方法可用的其他原因包括预期寿命延长,在伴侣之间分担生殖风险,社会问题,缺乏制药行业的参与,也缺乏倡导男性避孕的舆论制造者。
    目的:本指南旨在回顾男性避孕的现状,支持临床实践的最新技术,建议对新的男性避孕药具发展的最低要求,并提供和等级更新,欧洲男科学会(EAA)和美国男科学会(ASA)的循证建议。
    方法:由EAA和ASA任命的院士专家小组根据等级(建议的等级,评估,开发和评估)系统。
    结果:以夫妻为中心的交流产生了60项基于证据和分级的建议,行为,屏障方法,精液分析和避孕功效,物理代理,手术方法,在开始男性避孕之前的行动,荷尔蒙的方法,非荷尔蒙的方法,疫苗,以及社会和道德方面的考虑。
    结论:随着性别角色的转变和性别平等在人际关系中的确立,必须促进男性对计划生育的贡献。必须评估有效和安全的男性导向方法,并将其引入临床实践。最好是可逆的,荷尔蒙或非荷尔蒙。从未来的角度来看,识别新的荷尔蒙组合,合适的睾丸目标,和新出现的血管闭塞方法将产生新的分子和产品的男性避孕。
    BACKGROUND: Despite a wide spectrum of contraceptive methods for women, the unintended pregnancy rate remains high (45% in the US), with 50% resulting in abortion. Currently, 20% of global contraceptive use is male-directed, with a wide variation among countries due to limited availability and lack of efficacy. Worldwide studies indicate that >50% of men would opt to use a reversible method, and 90% of women would rely on their partner to use a contraceptive. Additional reasons for novel male contraceptive methods to be available include the increased life expectancy, sharing the reproductive risks among partners, social issues, the lack of pharma industry involvement and the lack of opinion makers advocating for male contraception.
    OBJECTIVE: The present guidelines aim to review the status regarding male contraception, the current state of the art to support the clinical practice, recommend minimal requirements for new male contraceptive development and provide and grade updated, evidence-based recommendations from the European Society of Andrology (EAA) and the American Society of Andrology (ASA).
    METHODS: An expert panel of academicians appointed by the EAA and the ASA generated a consensus guideline according to the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) system.
    RESULTS: Sixty evidence-based and graded recommendations were produced on couple-centered communication, behaviors, barrier methods, semen analysis and contraceptive efficacy, physical agents, surgical methods, actions before initiating male contraception, hormonal methods, non-hormonal methods, vaccines, and social and ethical considerations.
    CONCLUSIONS: As gender roles transform and gender equity is established in relationships, the male contribution to family planning must be facilitated. Efficient and safe male-directed methods must be evaluated and introduced into clinical practice, preferably reversible, either hormonal or non-hormonal. From a future perspective, identifying new hormonal combinations, suitable testicular targets, and emerging vas occlusion methods will produce novel molecules and products for male contraception.
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  • 文章类型: Randomized Controlled Trial
    背景:希望申请联合国人口基金/世界卫生组织(UNFPA/WHO)资格预审的新女性避孕套(FC)产品需要进行随机分组,对照临床研究将新的FC与上市的FC进行比较,以符合人口基金/世卫组织和国际标准化组织(ISO)的规范。我们的目标是评估功能性能,与对照FC2女性避孕套相比,Wondaleaf女性避孕套的可接受性和安全性。
    方法:这项随机临床试验在一个南非研究中心招募了220名女性。该研究的主要结果是女性避孕套(FC)的失败率。参与者被要求使用每种FC类型中的五种,并在家中收集避孕套日记中的使用信息,并在使用每种FC类型后进行了访谈。
    结果:证明了Wondaleaf相对于所有避孕套功能的参考FC2的非劣效性。Wondaleaf被发现优于FC2参考避孕套的内陷(p>.000),误导(p>.000)和临床失败(p>.000)。一系列特征的可接受性等级在两个FC之间是相似的。报告的任何一种设备的安全事件很少。
    结论:Wondaleaf的表现与FC2一样好,同样可以接受。这项研究的结果将进一步完善该FC设计。试用注册:ClinicalTrials.gov标识符:NCT04076774https://clinicaltrials.gov/。南非国家临床试验数据库(SANCTR)编号DOH-27-0319-6020。
    New female condom (FC) products wishing to apply for United Nations Population Fund/World Health Organisation (UNFPA/WHO) prequalification are required to conduct a randomized, controlled clinical investigation comparing the new FC to the marketed FC, in order to comply with UNFPA/WHO and International Organization for Standardization (ISO) specifications. We aimed to assess the functional performance, acceptability and safety of the Wondaleaf female condom compared to the control FC2 female condom.
    This randomized clinical trial enrolled 220 women in one South African site. The primary outcome of the study was the rate of female condom (FC) failure. Participants were asked to use five of each FC type and to collect information on use in a condom diary at home, and were interviewed after use of each FC type.
    Noninferiority was demonstrated for the Wondaleaf with respect to the reference FC2 for all condom functions. The Wondaleaf was found to be superior to the FC2 reference condom for invagination (p > .000), misdirection (p > .000) and clinical failure (p > .000). Acceptability ratings for a range of features were similar between the two FCs. Few safety events were reported for either device.
    The Wondaleaf performs as well as the FC2, and is equally acceptable. Results from this study will inform further refinement of this FC design. Trial registrations: ClinicalTrials.gov Identifier: NCT04076774 https://clinicaltrials.gov/. South African National Clinical Trials Database (SANCTR) number DOH-27-0319-6020.
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  • 文章类型: Journal Article
    UNASSIGNED: Family planning is a voluntary practice that individuals engage in to control the number of children for promoting the health and development of countries. The aim is to evaluate the level of contraceptive knowledge in Saudi males and females in Riyadh at King Abdul-Aziz Medical City (KAMC) and King Abdullah Specialist Children\'s Hospital (KASCH).
    UNASSIGNED: A cross-sectional questionnaire-based study conducted among educated, under educated, single, married Saudi males and females (n = 385), and aged (20 to 65) years old. Healthcare providers and participants underwent permanent sterilization were excluded.
    UNASSIGNED: Approximately half of the participants were aware about contraceptive methods. More males (n = 132, 70%) were significantly aware compared to females (n = 110, 56%) (P-value <0.001). The most commonly used contraceptive methods were oral contraceptive pills, male condom, and intrauterine device (69%, 34%, 22%, respectively). A significant difference was noted for the used and preferred contraceptive method, which was condom for male and oral contraceptive pills in female (P-value < 0.001). Healthcare provider was the main source of information and women significantly consult healthcare provider more than men 47% vs 32%, (χ2 = 9.23, P value = 0.002). Side effects were reported as a main reason for discontinuation 61% (n = 120) of females and 52% (n = 98) in males, respectively. Logistic regression indicated a significant association of contraceptive knowledge with age and parity.
    UNASSIGNED: Regardless of educational level, high levels of awareness were identified in both genders. Oral contraceptive pills were reported as the most used, safest, and preferred method.
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  • 文章类型: Journal Article
    Our primary objective was to evaluate whether new types of single-size diaphragms or cervical caps differ in prevention of pregnancy compared with older types of diaphragms, and whether different types of gels differ in their ability to prevent pregnancy. A secondary aim was to evaluate method discontinuation and complications.
    A comprehensive search was conducted in PubMed, Embase and the Cochrane Library. The certainty of evidence was assessed according to the GRADE system.
    Four randomised controlled studies were included in the assessment. When comparing the new and old types of female barrier contraceptives the 6-month pregnancy rate varied between 11%-15% and 8%-12%, respectively. More women reported inability to insert or remove the FemCap device (1.1%) compared with the Ortho All-Flex diaphragm (0%) (p<0.0306). Urinary tract infections were lower when using the single-size Caya, a difference of -6.4% (95% CI -8.9 to -4.09) compared with the Ortho All-Flex diaphragm. The 6-month pregnancy rate for acid-buffering gel and spermicidal nonoxynol-9 gel varied between 10% and 12%. The discontinuation rate was lower in women who used acid-buffering gel compared with nonoxynol-9 gel (risk ratio (RR) 0.77, 95% CI 0.68 to 0.97).
    Pregnancy rates were generally high in women using female barrier contraceptives. There was no difference in the efficacy for pregnancy prevention between the new types of diaphragms and cervical caps and the older diaphragms. The new types of diaphragms and cervical caps resulted in fewer urinary tract infections. Acid-buffering gels did not differ from spermicidal nonoxynol-9 gels regarding pregnancies but seemed to be better tolerated.
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  • 文章类型: Journal Article
    This study aimed to survey US servicewomen on their contraceptive access and use during deployment.
    Between June 2016 and July 2017, we conducted a cross-sectional online survey among a convenience sample of current and former members of the US Military, National Guard and Reserves who had a deployment ending in 2010 or later. Participants were asked open-ended and closed-ended questions about their demographics and contraceptive use and access before and during their last deployment. Descriptive statistics were run on closed-ended questions and responses to open-ended questions were inductively coded.
    A total of 353 participants were included. Sixty-five per cent reported using contraception during all or part of their last deployment. Nearly half (49.3%) did not have or remember having a discussion with a military care provider about contraception prior to deployment. Both prior to and during deployment, the free or low cost of birth control and ability to get a full supply for deployment facilitated contraceptive use. Difficulty obtaining an appointment and the inability to get a full supply of birth control were barriers to contraception access both before and during deployment. Half (49.1%) of respondents who had to start or refill contraception during deployment said it was somewhat or very difficult to do so.
    For at least some servicewomen, there are barriers to contraceptive access and use prior to and during overseas deployment. Programmes to increase contraceptive access should be expanded and monitoring systems should be implemented to ensure all servicemembers receive predeployment contraceptive counselling.
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  • 文章类型: Journal Article
    Even though fertility is reduced, conception and delivery are possible in all stages of CKD. While successful planned pregnancies are increasing, an unwanted pregnancy may have long-lasting deleterious effects, hence the importance of birth control, an issue often disregarded in clinical practice. The evidence summarized in this position statement is mainly derived from the overall population, or other patient categories, in the lack of guidelines specifically addressed to CKD. Oestroprogestagents can be used in early, non-proteinuric CKD, excluding SLE and immunologic disorders, at high risk of thromboembolism and hypertension. Conversely, progestin only is generally safe and its main side effect is intramestrual spotting. Non-medicated intrauterine devices are a good alternative; their use needs to be carefully evaluated in patients at a high risk of pelvic infection, even though the degree of risk remains controversial. Barrier methods, relatively efficacious when correctly used, have few risks, and condoms are the only contraceptives that protect against sexually transmitted diseases. Surgical sterilization is rarely used also because of the risks surgery involves; it is not definitely contraindicated, and may be considered in selected cases. Emergency contraception with high-dose progestins or intrauterine devices is not contraindicated but should be avoided whenever possible, even if far preferable to abortion. Surgical abortion is invasive, but experience with medical abortion in CKD is still limited, especially in the late stages of the disease. In summary, personalized contraception is feasible, safe and should be offered to all CKD women of childbearing age who do not want to get pregnant.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Comparative Study
    Objectives: We aimed to assess the functional performance and safety of a modified Woman\'s Condom (WC2) against the existing FC2 female condom. Study design: This randomized clinical trial enrolled 287 women in one South African site. The primary outcome of the study was the rate of female condom failure. Participants were asked to use five of each female condom type and to collect information on use in a condom log at home and were interviewed after use of each FC type. Results: Noninferiority was demonstrated for the WC2 with respect to the reference condom FC2 for all condom functions. The WC2 was found to be superior to the FC2 reference condom for clinical failure (p = .000), total female condom failure (p = .001), misdirection (p = .000) and slippage (p = .004). Conclusion: The WC2 female condom performs as well as the FC2 female condom and offers good stability during use. Implications: Results from this study will inform further refinement of this female condom design, resulting in a new and potentially less expensive Woman\'s Condom.
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