老年人身体活动量表(PASE)是评估老年人身体活动的有效测试。它还没有被调查,如果身体活动,根据PASE,与骨折风险相关,独立于FRAX中的临床风险因素(CRF),骨矿物质密度(BMD),合并症,如果这种关联是由于物理性能或骨骼参数的差异。这项研究的目的是评估PASE评分是否与骨骼特征相关,物理功能,从基于人群的横断面SUPERB研究中独立预测3014名75-80岁女性的骨折事件。在基线参与者回答问卷时,并接受了身体功能测试,用双x线吸收法进行详细的骨表型分析,和高分辨率外周定量计算机断层扫描。X线检查证实发生骨折。Cox回归模型用于评估PASE评分与骨折事件之间的关联。随着CRF的调整,FNBMD和Charlson合并症指数。根据PASE评分将女性分为四分位数。骨参数的四分位数差异(皮质体积BMD为1.56%,皮质面积为4.08%,Q4vs.Q1,分别为p=0.007和p=0.022)小于物理性能的四分位数差异(定时和去测试时间缩短了27%,一条腿站立时间延长52%,Q4vs.Q1)。在8年内(中位数,随访范围0.20-9.9),1077名妇女有骨折,806a主要骨质疏松性骨折(MOF;脊柱,臀部,前臂,肱骨),236例髋部骨折.第四季度的女性骨折风险降低了30%,MOF风险降低32%,髋部骨折的风险降低54%,与Q1的女性相比。这些关联仍然处于完全调整的模型中。总之,高体力活动与更好的身体机能和更低的骨折风险相关,MOF和髋部骨折,独立于FRAX中使用的风险因素,FNBMD和合并症。
老年人身体活动量表(PASE)是一种评估老年人身体活动的测试。这项研究的目的是评估身体活动,根据PASE,与骨骼参数相关联,物理功能,从基于人群的SUPERB研究中独立预测3014名75-80岁女性的未来骨折。在基线参与者回答问卷时,进行了身体功能测试和双X线吸收法。随后的骨折经X线证实。根据PASE评分将女性分为四分位数(Q1最少,Q4最活跃)。与第一季度相比,第四季度的女性计时和参加测试的时间缩短了27%,单腿站立时间延长了52%。在8年的随访中,1077名妇女有骨折,806a主要骨质疏松性骨折(MOF;脊柱,臀部,前臂,肱骨),236例髋部骨折.第四季度的女性骨折风险降低了30%,MOF风险降低32%,髋部骨折的风险降低54%,与Q1的女性相比。这些关联仍然存在于考虑合并症的模型中,骨密度和临床危险因素。总之,高体力活动与较好的身体机能和较低的骨折风险独立相关.
The Physical Activity Scale for the Elderly (PASE) is a validated test to assess physical activity in older people. It has not been investigated if physical activity, according to PASE, is associated with fracture risk independently from the clinical risk factors (CRFs) in FRAX, bone mineral density (BMD), comorbidity, and if such an association is due to differences in physical performance or bone parameters. The purpose of this study was to evaluate if PASE score is associated with bone characteristics, physical function, and independently predicts incident fracture in 3014 75-80-yr-old women from the population-based cross-sectional SUPERB study. At baseline, participants answered questionnaires and underwent physical function tests, detailed bone phenotyping with DXA, and high-resolution peripheral quantitative CT. Incident fractures were X-ray verified. Cox regression models were used to assess the association between PASE score and incident fractures, with adjustments for CRFs, femoral neck (FN) BMD, and Charlson comorbidity index. Women were divided into quartiles according to PASE score. Quartile differences in bone parameters (1.56% for cortical volumetric BMD and 4.08% for cortical area, Q4 vs Q1, p = .007 and p = .022, respectively) were smaller than quartile differences in physical performance (27% shorter timed up and go test, 52% longer one leg standing time, Q4 vs Q1). During 8 yr (median, range 0.20-9.9) of follow-up, 1077 women had any fracture, 806 a major osteoporotic fracture (MOF; spine, hip, forearm, humerus), and 236 a hip fracture. Women in Q4 vs. Q1 had 30% lower risk of any fracture, 32% lower risk of MOF, and 54% lower risk of hip fracture. These associations remained in fully adjusted models. In conclusion, high physical activity was associated with substantially better physical function and a lower risk of any fracture, MOF and hip fracture, independently of risk factors used in FRAX, FN BMD, and comorbidity.
The Physical Activity Scale for the Elderly (PASE) is a test to assess physical activity in older people. The purpose of this study was to evaluate if physical activity, according to PASE, is associated with bone parameters, physical function, and independently predicts future fracture in 3014 75–80-yr-old women from the population-based SUPERB study. At baseline, participants answered questionnaires, underwent physical function tests, and DXA. Subsequent fractures were X-ray verified. Women were divided into quartiles according to PASE score (Q1 least and Q4 most physically active). Women in Q4 had 27% shorter timed up and go test and 52% longer one leg standing time compared with Q1. During 8 yr of follow-up, 1077 women had any fracture, 806 a major osteoporotic fracture (MOF; spine, hip, forearm, humerus), and 236 a hip fracture. Women in Q4 vs. Q1 had 30% lower risk of any fracture, 32% lower risk of MOF, and 54% lower risk of hip fracture. These associations remained in models considering comorbidity, BMD, and clinical risk factors. In conclusion, high physical activity was independently associated with better physical function and a lower risk of any fracture.