未经证实:房室传导紊乱,需要永久性起搏器植入(PPI),代表经导管主动脉瓣植入术(TAVI)后的潜在并发症,然而,在这种情况下,人们对PPI后起搏器依赖性知之甚少.这篇系统综述分析了PPI的发病率,短期(1年)起搏依赖性,以及TAVI后这种状态的预测因子。
UNASSIGNED:我们在PUBMED中进行了系统搜索,EMBASE,和MEDLINE,以确定调查TAVI后PPI需求和依赖性的潜在相关文献。研究数据,病人,并提取了程序特征。提取具有95%置信区间的赔率比(OR)。
UNASSIGNED:数据来自23项研究,包括18,610名患者。TAVI后PPI的粗发生率为17%(范围,8.8%-32%)。PPI出现的中位时间为3.2天(范围,0-30天)。1年的起搏依赖性为47.5%(范围,7%-89%)。自膨式假体(合并OR为2.14[1.15-3.96])和基线右束支传导阻滞(合并OR为2.01[1.06-3.83])在TAVI后1年显示维持PPI依赖性的风险增加2倍。
未经评估:尽管PPI代表了TAVI之后相当频繁的事件,在出院后恢复和稳定的病例中,近50%的传导障碍具有暂时性。术前传导异常和TAVI类型与短期内较高的PPI依赖性相关。
UNASSIGNED: Atrioventricular conductions disturbances, requiring permanent pacemaker implantation (PPI), represent a potential complication after transcatheter aortic valve implantation (TAVI), However, little is known about the pacemaker dependency after PPI in this patient setting. This systematic review analyses the incidence of PPI, the short-term (1-year) pacing dependency, and predictors for such a state after TAVI.
UNASSIGNED: We performed a systematic search in PUBMED, EMBASE, and MEDLINE to identify potentially relevant literature investigating PPI requirement and dependency after TAVI. Study data, patients, and procedural characteristics were extracted. Odds ratio (OR) with 95% confidence intervals were extracted.
UNASSIGNED: Data from 23 studies were obtained that included 18,610 patients. The crude incidence of PPI after TAVI was 17% (range, 8.8%-32%). PPI occurred at a median time of 3.2 days (range, 0-30 days). Pacing dependency at 1-year was 47.5% (range, 7%-89%). Self-expandable prosthesis (pooled OR was 2.14 [1.15-3.96]) and baseline right bundle branch block (pooled OR was 2.01 [1.06-3.83]) showed 2-fold greater risk to maintain PPI dependency at 1 year after TAVI.
UNASSIGNED: Although PPI represents a rather frequent event after TAVI, conduction disorders have a temporary nature in almost 50% of the cases with recovery and stabilization after discharge. Preoperative conduction abnormality and type of TAVI are associated with higher PPI dependency at short term.