Autologous fat transfer

  • 文章类型: Journal Article
    背景:基于植入物的乳房重建是乳房重建的最普遍形式。自体脂肪移植(AFG)被概念化为基于植入物的乳房重建的替代方案,并被发现是一种可靠的重建方式。然而,通常,需要几轮移植来产生所需的乳房形状和大小。当前文献描述了AFG作为基于植入物的乳房重建以改善外观的辅助手段的丰富经验。然而,初始AFG后乳房植入物的使用很少描述。这项研究的主要优点是创造了新的脂肪组织作为乳房丘。然后通过将植入物插入该新土墩中来结束重建。这种方法减少了实现预期结果所需的脂肪注射的总数。以及植入物的总体积。
    方法:这项IRB批准的回顾性研究于2015年1月至2021年12月进行。在此时间段内接受AFG延迟乳房重建并希望以硅胶植入物作为最后阶段完成乳房重建的所有女性都包括在研究中。
    结果:共有29例患者(33例乳房)接受了以AFG和硅胶植入物为最后阶段的延迟乳房重建。在所有情况下,结果令人满意,无任何重大并发症.在一名患者中观察到次要并发症,包括感染。
    结论:这项研究的结果证明了该程序的有效性以及患者的满意度。从而突出了这种方法提供的潜在优势。
    方法:本期刊要求作者为每篇文章分配一定程度的证据。对于这些循证医学评级的完整描述,请参阅目录或在线作者说明www。springer.com/00266.
    BACKGROUND: Implant-based breast reconstruction is the most prevalent form of breast reconstruction. Autologous fat grafting (AFG) was conceptualized as an alternative to implant-based breast reconstruction and was found to be a reliable reconstruction modality. However, usually, a few grafting rounds are required to create the desired shape and size of the breast. Current literature describes ample experience with AFG as an adjunct to implant-based breast reconstruction for improving appearance. However, the utilization of breast implants following initial AFG has been sparingly described. The primary advantage of this study is the creation of new fat tissue as a breast mound. The reconstruction is then concluded by inserting an implant into this new mound. This approach reduces the overall number of fat injections needed to achieve the desired outcome, as well as the total volume of the implant.
    METHODS: This IRB-approved retrospective study was conducted between January 2015 and December 2021. All women who underwent delayed breast reconstruction with AFG during this timeframe and wanted to complete it with a silicone implant as a last stage were included in the study.
    RESULTS: A total of 29 patients (33 breasts) underwent delayed breast reconstruction with AFG and a silicone implant as the final stage. In all cases, the results were satisfying without any major complications. Minor complications were observed with one patient and included an infection.
    CONCLUSIONS: The findings of this study have demonstrated the effectiveness of this procedure together with patient satisfaction, thus highlighting the potential advantages that this approach offers.
    METHODS: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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  • 文章类型: Journal Article
    背景:巴西屁股提升(BBL)是一种安全的技术,需要通过自体脂肪转移通过臀部增强进行身体重塑。
    方法:在2018年至2022年之间,3000例患者接受了手术。每次手术都是从患者仰卧位开始的,从腹部抽脂开始,然后脂肪转移到臀部。随后,患者被重新定位为俯卧姿势。背部和腰部的吸脂术随之而来,结束脂肪转移到臀部的手术。实施严格的预防措施以确保患者在整个过程中的安全。
    结果:86%的患者对其结果表示满意,而百分之七十的转移脂肪在臀部存活。遇到了一个严重的并发症和一些次要的并发症,并通过保守措施得到了有效的管理。
    结论:BBL被证明是一种安全和令人满意的手术,由有经验的外科医生坚持基本原则。证据级别3:本期刊要求作者为每篇文章指定一个级别的证据。对于这些循证医学评级的完整描述,请参阅目录或在线作者说明www。springer.com/00266.
    BACKGROUND: The Brazilian Butt Lift (BBL) is a safe technique that entails body reshaping through buttock augmentation using autologous fat transfer.
    METHODS: Between 2018 and 2022, 3000 patients underwent surgery. Each procedure commenced with the patient in supine position, starting with abdominal liposuction, followed by fat transfer to hips. Subsequently, the patient was repositioned to a prone stance. Liposuction of the back and waist ensued, concluding the surgery with fat transfer to the buttocks. Stringent precautions were implemented to ensure the safety of the patient throughout the procedure.
    RESULTS: Eighty-six percent of patients express satisfaction with their outcomes, while seventy percent of the transferred fat calls survive in the buttocks. One serious complication and some minor complications have been encountered and effectively managed through conservative measures.
    CONCLUSIONS: BBL proves to be a safe and satisfactory surgery when performed by experienced surgeons who adhere to fundamental principles. LEVEL OF EVIDENCE 3: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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  • 文章类型: Systematic Review
    脂肪转移越来越多地用作我们重建医疗设备的一部分,以解决烧伤伤口和重建手术中遇到的挑战。本系统评价旨在评估自体脂肪转移在急性烧伤创面处理中的有效性。对美国国家医学图书馆的系统评价,科克伦图书馆,WebofScience,Embase于2022年10月15日进行(注册号为CDR42022369726)。进行数据库监视,直到提交手稿。审查的重点是伤口愈合。包括所有报告患有深2度烧伤伤口的成年患者(至少报告了5名患者)的脂肪转移的研究。数据库搜索共产生720条记录,包括3项研究中的367名患者。疤痕质地有统计学意义的改善,疤痕外观,与对照组相比,一项研究报告了脂肪转移组的愈合时间(P<0.001)。同样,疤痕颜色的分数,疤痕厚度,疤痕硬度,瘢痕规律性明显增加。纳入的研究数量少,异质性不允许进行荟萃回归。本系统评价强调了目前关于使用自体脂肪转移改善成年患者烧伤伤口愈合的有限证据。尽管看起来很有希望。未来的研究应该集中在有更多参与者的随机对照试验上。
    Fat transfer is increasingly used as part of our reconstructive armamentarium to address the challenges encountered in burn wounds and reconstructive surgery. The present systematic review aimed to evaluate the effectiveness of autologous fat transfer for acute burn wound management. A systematic review of the US National Library of Medicine, Cochrane Library, Web of Science, and Embase was conducted on October 15, 2022 (registration number CDR42022369726). A database watch was performed until submission of the manuscript. The review focused on wound healing. All studies reporting fat transfer in adult patients (at least 5 patients reported) with deep 2nd degree burn wounds were included. The database search yielded a total of 720 records and 367 patients were included from 3 studies. A statistically significant improvement in scar texture, scar appearance, and time to healing was reported in one study in the fat transfer group versus control (P<0.001). Similarly, scores for scar color, scar thickness, scar stiffness, and scar regularity increased significantly. The small number of included studies and their heterogeneity did not allow a meta-regression to be performed. This systematic review emphasizes the limited evidence currently available regarding the use of autologous fat transfer to improve burn wound healing in adult patients, even though it seems promising. Future search should focus on randomized controlled trials with a larger number of participants.
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  • 文章类型: Systematic Review
    自成立以来,臀肌增强已成为一种流行的美学程序。主要方法是使用植入物或自体脂肪移植来增强,也就是采集和移植病人自己的脂肪组织。上次比较这些方法的安全性的评论是7年前写的,这就需要写一个新的。PubMed,科克伦,和Medline进行了搜索,以关注先前列出的臀肌增强方法。使用了五个搜索词,15项研究符合标准。根据描述的方法对数据进行分类,并比较结果。七篇文章聚焦于臀肌植入物,另外七篇评估了自体脂肪移植,而一个详细说明了两者。524例植入手术中最常见的并发症是伤口裂开(9.16%),种植体触诊过度(5.92%),和血清肿(3.82%),总并发症发生率为25%。1788年臀位脂肪增加术中最常见的并发症是血清肿(6.9%),感染(3.0%),短暂性坐骨神经感觉异常(1.0%),总并发症发生率为13%。几篇文章列出了满意度数字,但未对这些结果进行评估,因为本文没有能力评估这一结果.总的来说,与植入物相比,使用自体脂肪移植进行臀部增强可减少术后并发症,并使臀部和周围区域的轮廓更大。然而,如果不遵循某些建议,这也可能是一个更加危险的程序。
    Gluteal augmentation has become a popular esthetic procedure since its inception. The main methods are augmentation using implants or autologous fat grafting, which is the harvesting and grafting of patients\' own fat tissue. The last review comparing the safety of these methods was written 7 years ago, which warrants the writing of a new one. PubMed, Cochrane, and Medline were searched for studies focusing on the methods of gluteal augmentation listed previously. Five search terms were used and 15 studies fulfilled the criteria. The data were cataloged according to the method described and outcomes compared. Seven articles focused on gluteal implants and another seven assessed autologous fat grafting, whereas one detailed both. The most common complications in 524 implant procedures were wound dehiscence (9.16%), excessive implant palpability (5.92%), and seroma (3.82%), with an overall complication rate of 25%. The most common complications in 1788 gluteal fat augmentation procedures were seroma (6.9%), infection (3.0%), and transient sciatic paresthesia (1.0%), with an overall complication rate of 13%. Several articles listed satisfaction figures, but these were not assessed because this article was not powered to assess this outcome. Overall, gluteal augmentation using autologous fat grafting leads to fewer postoperative complications than implants and allows greater contouring of the buttocks and the surrounding areas. However, it can also be a far more dangerous procedure if certain recommendations are not followed.
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  • 文章类型: Case Reports
    一名52岁的女性患者在通过腹部自体脂肪移植进行最小的颅骨悬吊(MACS)抬起后三周出现面部脂肪坏死,并伴有皮肤硬结。鉴于患者在手术后一周接受了ModernaSARS-CoV-2疫苗,我们假设前者易导致组织缺血导致脂肪坏死。活检后的组织学结果与脂肪坏死一致,其中包括明显的皮肤纤维化和局灶性脂肪坏死区域,噬菌体,多核巨细胞,和铁皮噬菌体。我们希望在文献中记录这种罕见的发展可以鼓励SARS-CoV-2疫苗施用后的不良反应报告,并可以通过监管机构加强对其他健康后果的检查和监测。
    A 52-year-old female patient developed facial fat necrosis presenting with cutaneous induration three weeks after minimal access cranial suspension (MACS) lift with autologous fat grafting from the abdomen. Given that the patient received the Moderna SARS-CoV-2 vaccine one week after surgery, we hypothesize that the former predisposed her to tissue ischemia leading to fat necrosis. Histological findings after biopsy were consistent with fat necrosis, which included marked dermal fibrosis with areas of focal fat necrosis, lipophages, multinucleated giant cells, and siderophages. It is our hope that documenting this rare development in literature may serve as encouragement for adverse effect reporting after the SARS-CoV-2 vaccine administration and may boost inspection and monitoring of other health consequences by regulating agencies.
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  • 文章类型: Case Reports
    我们介绍了一名23岁的男性患者,患有严重的PS,以明显的左胸壁畸形为特征。使用脂肪增强背阔肌皮瓣进行重建,固定在胸壁上,与胸大肌缺失的地方相对应。患者对最终的美学和功能结果感到满意。
    We present a 23-year-old male patient with severe PS, characterized by marked left thoracic wall deformity. Reconstruction was performed using the Fat-Augmented Latissimus Dorsi flap, which was fixed to the chest wall hollowing corresponding to where the pectoralis major muscle was missing. Patient was satisfied with final aesthetic and functional result.
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  • 文章类型: Case Reports
    暂无摘要。
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  • 文章类型: Journal Article
    狼疮性脂膜炎(LP)通常表现为触痛结节和间歇性溃疡,然后伴随瘢痕和脂肪萎缩而愈合。目前的治疗主要是医疗。关于用自体脂肪移植治疗LP脂肪萎缩的研究是有限的。我们想分享我们在这种罕见情况下的经验,用自体脂肪转移治疗。一名48岁女性出现红斑,嫩结节,以及左颞区病变凹陷后的溃疡。患者的左脸颊也有硬结红斑。两种病变均因阳光照射而加重。经过多次调查,她被诊断为LP,在她的左颞叶和左脸颊患有继发性脂肪萎缩和肿瘤性红斑狼疮,分别。她接受了抗疟药和局部类固醇。患者接受了两次自体脂肪转移。注射8和3.7mL脂肪后,她对疤痕的体积和轮廓改善感到满意。此外,该患者报告自第一次脂肪移植注射以来,结节和溃疡的疼痛缓解。总之,自体脂肪转移是一种简单有效的治疗LP继发脂肪萎缩和瘢痕的方法,效果良好.
    Lupus panniculitis (LP) often presents with tender nodules and intermittent ulcers that then heal with scarring and lipoatrophy. The current mainstay of treatment is medical treatment. Research regarding the treatment of lipoatrophy from LP with autologous fat grafting is limited. We would like to share our experience in this rare case, which was treated with autologous fat transfer. A 48-year-old female presented with erythematous plaque, tender nodules, and ulcers following by a depression of the lesion at the left temporal area. The patient also had indurated erythematous plaque at her left cheek. Both lesions were aggravated by sunlight exposure. After several investigations, she was diagnosed as LP with secondary lipoatrophy and tumid lupus erythematosus at her left temporal and left cheek, respectively. She received antimalarial drug and topical steroids. The patient underwent two sessions of autologous fat transfer. She was satisfied with the volume and contour improvement in the scar following the injection of 8 and 3.7 mL of fat. Furthermore, the patient reported the remission of tender nodules and ulcers since the first fat graft injection. In conclusion, the autologous fat transfer is a simple and effective treatment for lipoatrophy and scar secondary to LP with promising results.
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  • 文章类型: Journal Article
    自体脂肪移植在隆胸或乳房重建中很常见。然而,尚未仔细研究用于脂肪移植的乳房中的AFG受体部位。
    40名需要隆胸脂肪移植的女性患者被随机分为两组。乳腺后组接受2/3的脂肪进入乳腺后间隙,其他1/3的脂肪进入皮下和胸后平面。胸后组接受2/3脂肪进入胸后平面,其他1/3脂肪进入皮下和乳腺后平面。通过3D激光表面扫描然后超声评估6个月时的脂肪移植结果。随访期间记录所有并发症。从接受脂肪移植6个月的患者获得样品并进行组织学检查。
    两组在6个月后的保留率没有显着差异(乳后组:35.9%±6.6;胸后组:39.3%±5.1,p=0.1076)。乳后组的油囊肿形成发生率高于胸后组。组织学检查显示,乳腺后组脂肪细胞中有较多的油囊肿和mac2阳性巨噬细胞浸润,而胸后组的小脂肪细胞较多。
    尽管将脂肪移植到胸后平面并没有提供优越的脂肪移植保留率,它确实降低了并发症的发生率。胸后空间显示出很大的潜力,成为一个有利的接收地点。
    UNASSIGNED: Autologous fat transfer is common in breast augmentationor reconstruction. However, AFG recipient site in the breast for fat grafting has not been carefully investigated.
    UNASSIGNED: Forty female patients requiring breast augmentation with fat grafting were randomly assigned into two groups. The retromammary group received 2/3 fat into the retromammary space and the other 1/3 into the subcutaneous and retropectoral planes. The retropectoral group received 2/3 fat into the retropectoral plane and the other 1/3 into the subcutaneous and retromammary planes. The fat grafting result at 6 months was assessed by 3D laser surface scanning and then ultrasound. Any complications were recorded during follow-up. Samples from a patient who underwent fat grafting for 6 months was obtained and histological examination was conducted.
    UNASSIGNED: No significant difference in the retention rate after 6 months was observed between the two groups (retromammary group: 35.9% ± 6.6; retropectoral group: 39.3% ± 5.1, p = 0.1076). The retromammary grouphad a higher incidence of oil cyst formation than the retropectoral group. Histological examination showed that there were more oil cysts and mac2 positive macrophage infiltration in the fat cells in retromammary group, while retropectoral group had more small-size adipocytes.
    UNASSIGNED: Although fat grafting into the retropectoral plane did not provide a superior fat graft retention rate, it did lower the incidence of complications. The retropectoral space show great potential to become a favorable recipient site.
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  • 文章类型: Case Reports
    一名59岁的女性,之前有双侧下眼睑自体脂肪转移,皮下微针和部分射频皮肤表面置换表现为延迟的左侧前板蜂窝织炎,小的多结节脓肿对口服门诊抗生素方案和住院静脉抗生素无反应。伤口培养显示,用克拉霉素和替地唑胺4个月的方案成功治疗了龟分枝杆菌感染,没有复发。该病例强调(1)需要警惕和广泛差异延迟的术后伤口感染,包括非结核性分枝杆菌感染,(2)应用克拉霉素和新型替迪唑胺口服抗生素治疗,和(3)当进行联合自体脂肪转移与皮下微针刺程序时,应谨慎行事,因为皮肤完整性的破坏可能会加剧感染。
    A 59-year-old woman with prior bilateral lower eyelid autologous fat transfer, subdermal micro-needling and fractional radiofrequency skin resurfacing presented with delayed left-sided preseptal cellulitis with small multinodular abscesses unresponsive to oral outpatient antibiotic regimens and inpatient intravenous antibiotics. Wound culture revealed Mycobacterium chelonae infection treated successfully with a 4-month regimen of clarithromycin and tedizolid without recurrence. This case highlights (1) the need for vigilance and a broad differential in delayed post-operative wound infections including non-tuberculous mycobacterial infections, (2) resolution of infection without recurrence on clarithromycin and novel tedizolid oral antibiotic therapy, and (3) that caution should be exercised when performing combination autologous fat transfers with subdermal micro-needling procedures as the breakdown in skin integrity may potentiate infection.
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