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  • 文章类型: Journal Article
    背景:植入物的体积是乳房重建的最关键要素,因此,有必要准确评估健康和受影响的乳房的术前体积,并选择合适的植入物进行放置。用于定量评估乳房体积的准确和自动化方法可以优化乳房重建手术并帮助医生进行临床决策。这项研究的目的是开发一种人工智能模型,用于自动分割乳房和测量体积。
    方法:本研究共纳入249名接受乳房再造手术的受试者。受试者术前接受乳腺MRI检查,并且由成像医师手动勾勒出的乳房区域作为通过自动分割模型进行体积测量的金标准。在这项研究中,我们开发了三种自动分割乳房区域的自动算法,包括一个简单的对齐模型,对齐动态编码模型,和深度学习模型。通过计算均方误差(MSE)和组内相关系数(ICC)来评估三种自动分割算法与影像医师手动分割的乳房区域之间的体积一致性。并且通过测试-重测步骤评估乳房区域自动分割的可重复性。
    结果:本研究开发的三种乳房自动分割模型(简单配准模型,动态规划模型,和深度学习模型)显示出强大的ICC,手动分割乳腺区域,MSEs为1.124、0.693和0.781,ICC为0.975(95%CI,0.869-0.991),0.986(95%CI,0.967-0.996),和0.983(95%CI,0.961-0.992),分别。关于乳房体积的重测结果,动态规划模型表现最好,MSE为0.370,ICC为0.993(95%CI,0.982-0.997),其次是深度学习算法,MSE为0.741,ICC为0.983(95%CI,0.956-0.993),和简单的配准算法,MSE为0.763,ICC为0.982(95%CI,0.949-0.993)。三种自动算法分割的乳房区域的再现性高于不同放射科医师的手动分割。
    结论:本研究中开发的三种自动乳房分割算法可生成准确可靠的乳房区域,实现高度可重复的乳房区域分割和自动体积测量,并为手术选择合适的假体提供了有价值的工具。
    方法:本期刊要求作者为每个提交的证据分配一个级别,该级别的证据适用于循证医学排名。这不包括评论文章,书评,和有关基础科学的手稿,动物研究,尸体研究,和实验研究。对于这些循证医学评级的完整描述,请参阅目录或在线作者说明www。springer.com/00266.
    BACKGROUND: The volume of the implant is the most critical element of breast reconstruction, so it is necessary to accurately assess the preoperative volume of the healthy and affected breasts and select the appropriate implant for placement. Accurate and automated methods for quantitative assessment of breast volume can optimize breast reconstruction surgery and assist physicians in clinical decision making. The aim of this study was to develop an artificial intelligence model for automated segmentation of the breast and measurement of volume.
    METHODS: A total of 249 subjects undergoing breast reconstruction surgery were enrolled in this study. Subjects underwent preoperative breast MRI, and the breast region manually outlined by the imaging physician served as the gold standard for volume measurement by the automated segmentation model. In this study, we developed three automated algorithms for automatic segmentation of breast regions, including a simple alignment model, an alignment dynamic encoding model, and a deep learning model. The volumetric agreement between the three automated segmentation algorithms and the breast regions manually segmented by imaging physicians was evaluated by calculating the mean square error (MSE) and intragroup correlation coefficient (ICC), and the reproducibility of the automated segmentation of the breast regions was assessed by the test-retest step.
    RESULTS: The three breast automated segmentation models developed in this study (simple registration model, dynamic programming model, and deep learning model) showed strong ICC with manual segmentation of the breast region, with MSEs of 1.124, 0.693, and 0.781, and ICCs of 0.975 (95% CI, 0.869-0.991), 0.986 (95% CI, 0.967-0.996), and 0.983 (95% CI, 0.961-0.992), respectively. Regarding the test-retest results of breast volume, the dynamic programming model performed the best with an MSE of 0.370 and an ICC of 0.993 (95% CI, 0.982-0.997), followed by the deep learning algorithm with an MSE of 0.741 and an ICC of 0.983 (95% CI, 0.956-0.993), and the simple registration algorithm with an MSE of 0.763 and an ICC of 0.982 (95% CI, 0.949-0.993). The reproducibility of the breast region segmented by the three automated algorithms was higher than that of manual segmentation by different radiologists.
    CONCLUSIONS: The three automated breast segmentation algorithms developed in this study generate accurate and reliable breast regions, enable highly reproducible breast region segmentation and automated volume measurements, and provide a valuable tool for surgical selection of appropriate prostheses.
    METHODS: This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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  • 文章类型: Journal Article
    生成对抗网(GAN)是一种变革性的深度学习框架,已被频繁地应用于与图像处理相关的各种应用程序,视频,演讲,和文本。然而,GAN仍然遭受诸如模式崩溃和训练不稳定的缺点。为了应对这些挑战,本文提出了一种自动编码GAN,它由一组发电机组成,一个鉴别器,编码器,还有一个解码器.一组发电机负责学习各种模式,鉴别器用于区分真实样本和生成样本。编码器将生成的样本和真实样本映射到嵌入空间,以编码可区分的特征,并且解码器确定生成的样本来自哪个生成器以及真实样本来自哪个模式。它们在训练中被联合优化以增强特征表示。此外,采用聚类算法来感知真实样本和生成样本的分布,并相应地构造了聚类中心匹配的算法,以保持分布的一致性,从而防止多个发电机覆盖某一模式。对两类数据集进行了广泛的实验,结果直观和定量地证明了所提出的模型在减少模式崩溃和增强特征表示方面的良好能力。
    Generative Adversarial Nets (GANs) are a kind of transformative deep learning framework that has been frequently applied to a large variety of applications related to the processing of images, video, speech, and text. However, GANs still suffer from drawbacks such as mode collapse and training instability. To address these challenges, this paper proposes an Auto-Encoding GAN, which is composed of a set of generators, a discriminator, an encoder, and a decoder. The set of generators is responsible for learning diverse modes, and the discriminator is used to distinguish between real samples and generated ones. The encoder maps generated and real samples to the embedding space to encode distinguishable features, and the decoder determines from which generator the generated samples come and from which mode the real samples come. They are jointly optimized in training to enhance the feature representation. Moreover, a clustering algorithm is employed to perceive the distribution of real and generated samples, and an algorithm for cluster center matching is accordingly constructed to maintain the consistency of the distribution, thus preventing multiple generators from covering a certain mode. Extensive experiments are conducted on two classes of datasets, and the results visually and quantitatively demonstrate the preferable capability of the proposed model for reducing mode collapse and enhancing feature representation.
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  • 文章类型: Journal Article
    为了防止新冠肺炎感染在不同国家的爆发,许多组织和政府广泛研究和应用了各种隔离检疫政策,医疗以及为18岁以上公民组织的大规模/快速疫苗接种策略。在这场Covid-19战役中,不同国家取得了一些宝贵的经验教训。这些研究提出了在测试中迅速行动的有用性,通过数据驱动的预测,从社区隔离确诊的感染病例以及社会资源规划/优化。最近,许多研究已经证明了短期/长期预测对时间序列数据形式的新Covid-19病例数量的有效性。这些预测直接支持有效优化可用的医疗资源,并实施合适的政策来减缓新冠肺炎的传播,特别是在人口稠密的城市/地区/国家。深度神经架构有几个进展,例如递归神经网络(RNN)在分析和学习时间序列数据集以进行更好的预测方面已经证明了显着的改进。然而,大多数最新的基于RNN的技术被认为无法处理混沌/非平滑的序列数据集。来自混沌时间序列数据集的连续干扰和滞后观察,如常规新冠肺炎确诊病例,导致最近基于RNN的模型在时间特征学习过程中的性能低下。为了迎接这一挑战,在本文中,我们提出了一种新颖的基于双注意力的顺序自动编码架构,称为:DAttAE。我们提出的模型支持以混沌和非平稳时间序列数据集的形式有效地学习和预测新的Covid-19案例。具体来说,在我们提出的模型中,基于给定Bi-LSTM的自动编码器中的双重自注意机制之间的集成支持将模型直接聚焦在特定的时间范围序列上,以实现更好的预测。我们通过与多种传统和最先进的基于深度学习的技术进行比较,评估了我们提出的DAttAE模型的性能,这些技术用于不同现实世界数据集上的时间序列预测任务。实验结果证明了我们提出的基于注意力的深度神经方法与最先进的基于RNN的架构相比的有效性,用于基于时间序列的新冠肺炎疫情预测任务。
    For preventing the outbreaks of Covid-19 infection in different countries, many organizations and governments have extensively studied and applied different kinds of quarantine isolation policies, medical treatments as well as organized massive/fast vaccination strategy for over-18 citizens. There are several valuable lessons have been achieved in different countries this Covid-19 battle. These studies have presented the usefulness of prompt actions in testing, isolating confirmed infectious cases from community as well as social resource planning/optimization through data-driven anticipation. In recent times, many studies have demonstrated the effectiveness of short/long-term forecasting in number of new Covid-19 cases in forms of time-series data. These predictions have directly supported to effectively optimize the available healthcare resources as well as imposing suitable policies for slowing down the Covid-19 spreads, especially in high-populated cities/regions/nations. There are several progresses of deep neural architectures, such as recurrent neural network (RNN) have demonstrated significant improvements in analyzing and learning the time-series datasets for conducting better predictions. However, most of recent RNN-based techniques are considered as unable to handle chaotic/non-smooth sequential datasets. The consecutive disturbances and lagged observations from chaotic time-series dataset like as routine Covid-19 confirmed cases have led to the low performance in temporal feature learning process through recent RNN-based models. To meet this challenge, in this paper, we proposed a novel dual attention-based sequential auto-encoding architecture, called as: DAttAE. Our proposed model supports to effectively learn and predict the new Covid-19 cases in forms of chaotic and non-smooth time series dataset. Specifically, the integration between dual self-attention mechanism in a given Bi-LSTM based auto-encoder in our proposed model supports to directly focus the model on a specific time-range sequence in order to achieve better prediction. We evaluated the performance of our proposed DAttAE model by comparing with multiple traditional and state-of-the-art deep learning-based techniques for time-series prediction task upon different real-world datasets. Experimental outputs demonstrated the effectiveness of our proposed attention-based deep neural approach in comparing with state-of-the-art RNN-based architectures for time series based Covid-19 outbreak prediction task.
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  • 文章类型: Journal Article
    本文重点研究了一种基于目标辐射噪声的水声目标识别方法。水声目标识别的难点主要是有效分类特征的提取和模式分类。传统的基于低频分析记录(LOFAR)的特征提取方法,梅尔频率倒谱系数(MFCC),Gammatone频率倒谱系数(GFCC),等。本质上是根据某个预先设定的模型压缩数据,人为丢弃数据中的部分信息,并且经常丢失有助于分类的信息。提出了一种基于特征自动编码的目标识别方法。该方法以信号的归一化频谱为输入,使用受限玻尔兹曼机执行数据的无监督自动编码,逐层提取深层数据结构,并通过BP神经网络对获取的特征进行分类。利用实际舰船辐射噪声数据库对该方法进行了测试,结果表明,与基于手工特征提取的方法相比,本文提出的分类系统具有更好的识别精度和适应性。
    This article focuses on an underwater acoustic target recognition method based on target radiated noise. The difficulty of underwater acoustic target recognition is mainly the extraction of effective classification features and pattern classification. Traditional feature extraction methods based on Low Frequency Analysis Recording (LOFAR), Mel-Frequency Cepstral Coefficients (MFCC), Gammatone-Frequency Cepstral Coefficients (GFCC), etc. essentially compress data according to a certain pre-set model, artificially discarding part of the information in the data, and often losing information helpful for classification. This paper presents a target recognition method based on feature auto-encoding. This method takes the normalized frequency spectrum of the signal as input, uses a restricted Boltzmann machine to perform unsupervised automatic encoding of the data, extracts the deep data structure layer by layer, and classifies the acquired features through the BP neural network. This method was tested using actual ship radiated noise database, and the results show that proposed classification system has better recognition accuracy and adaptability than the hand-crafted feature extraction based method.
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