目的:本加榕树(FB)是印度医学系统中描述的一种流行植物。传统上,它用于治疗糖尿病等疾病,痢疾,白带,月经过多,皮肤病,风湿病,炎症性疾病,血液疾病。本文根据抗凝血剂等特性,强调了FB的抗血栓作用。血小板抗聚集,抗动脉粥样硬化降压,降血脂,抗氧化剂,抗炎和免疫调节。
方法:已在科学数据库中搜索了与FB有关的所有可用数据,包括PubMed,谷歌学者,ScienceDirect和Scopus。
结果:FB是丰富的有机化合物,例如酚类,黄酮类化合物,生物碱,单宁,萜类和类固醇。各种研究表明,这些植物化学成分表现出广泛的抗血栓作用,如抗凝剂,血小板抗聚集,抗动脉粥样硬化,降血脂,低血压,抗炎,和抗氧化剂。
结论:各种研究(体外和体内)证实了FB的潜在抗血栓形成益处,这是由于已经证明在血栓栓塞情况下有效的化学结构的存在。这些证据可能有益于新药开发以治疗各种血栓栓塞疾病,这不仅具有成本效益,而且可以减轻对副作用的恐惧。
Ficus benghalensis L. (FB) is a popular plant described in the Indian system of medicine. Traditionally, it is indicated in the treatment of diseases like diabetes mellitus, dysentery, leucorrhoea, menorrhagia, skin disease, rheumatism, inflammatory diseases, blood disorders. This paper accentuates the anti-thrombotic action of FB based on the properties like anti-coagulant, platelet-antiaggregatory, anti-atherogenic hypotensive, hypolipidemic, anti-oxidant, anti-inflammatory and immunomodulatory. All the available data pertaining to FB has been searched in the scientific databases, including PubMed, Google Scholar, ScienceDirect and Scopus. FB is a rich lode of organic compounds such as phenols, flavonoids, alkaloids, tannins, terpenoids and steroids. The various studies show that these phytochemical constituents exhibit wide range of anti-thrombotic actions such as anticoagulant, platelet anti-aggregatory, anti-atherogenic, hypolipidemic, hypotensive, anti-inflammatory, and antioxidant. Various studies (in vitro and in vivo) confirm the potential anti-thrombotic benefit of FB due to the presence of chemical structures that have proven to be effective in thromboembolic conditions. These evidences may benefit in new drug development to treat varied thromboembolic conditions which will not only be cost effective but may allay the fear of side effects.