■黄花蒿(AA),用作家禽的生长促进剂,降低饲料成本,提高经济效益。本研究旨在评估不同AA浓度对肉鸡生长的影响,基因表达,和盈利能力。
■将200只1日龄的Cobb雄性小鸡随机分为四个治疗组,每个包含5个重复和10只鸟。实验组由G1(基础饮食)组成,G2(含0.3%AA的基础饮食),G3(含0.6%AA的基础饮食),和G4(含0.9%AA的基础饮食)。在整个研究过程中,鸟类可以连续获取饲料和水。实验持续了42天。我们测量了生长性能(饲料摄入量,Lifeweight),屠体性状(屠宰后的体重,穿着的尸体,心,Gizzard,脾,脾内脏和胸腺重量),肝脏和脾脏抗氧化剂(CAT,GSH,SOD),以及抗炎和免疫相关基因的基因表达。
■主要发现表明,与对照组和其他组相比,添加0.6%AA对所有调查变量都有积极影响(p<0.05)。膳食补充0.6%AA导致乳房增加,giblet,骷髅,和总产量,和净收益率与对照组相比。补充AA表现出抗氧化剂,抗炎,通过提高抗氧化超氧化物歧化酶(SOD)的水平,过氧化氢酶(CAT),肝脏和脾脏组织匀浆中的谷胱甘肽过氧化物酶(GSH-Px)。它还上调了抗炎白细胞介素(IL)-10,SOD的相对信使RNA水平,CAT,和GSH-Px,而IL-1β和肿瘤坏死因子-α下调。
■研究发现,AA是家禽养殖中抗生素的有希望的替代品,可作为鸡的生长促进剂。0.6%AA在肉鸡日粮中产生了最好的结果,在卓越的性能和强大的经济效益之间取得平衡。
UNASSIGNED: Artemisia annua (AA), used as a growth promoter in poultry, lowers feed costs and enhances economic efficiency. This study aimed to assess the impact of varying AA concentrations on broiler chicken growth, gene expression, and profitability.
UNASSIGNED: Two hundred 1-day-old male Cobb chicks were randomly allocated into four treatment groups, each containing five replicates and 10 birds. The experimental groups consisted of G1 (basal diet), G2 (basal diet with 0.3% AA), G3 (basal diet with 0.6% AA), and G4 (basal diet with 0.9% AA). The birds had continuous access to feed and water throughout the study. The experiment lasted for 42 days. We measured the growth performance (Feed intake, Life weight), carcass traits (weight after slaughter, dressed carcass, heart, gizzard, spleen, giblet and thymus weight), liver and spleen antioxidants (CAT, GSH, SOD), and gene expression of anti-inflammatory and immune- related genes.
UNASSIGNED: The primary findings revealed that the addition of 0.6% AA had a positive impact (p < 0.05) on all investigated variables compared with the control and other groups. Dietary supplementation with 0.6% AA led to increased breast, giblet, skeleton, and total yield, and net return compared with the control group. Supplementation with AA exhibited antioxidant, anti-inflammatory, and immunological effects through improved levels of antioxidant superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) in tissue homogenates of the liver and spleen. It also upregulated the relative messenger RNA levels of anti-inflammatory interleukin (IL)-10, SOD, CAT, and GSH-Px, whereas IL-1β and tumor necrosis factor-alpha were downregulated.
UNASSIGNED: The study found that AA is a promising replacement for antibiotics in poultry farming as a growth promoter for chickens. 0.6% AA in the broiler diet yielded the best results, striking a balance between superior performance and robust economic benefits.