神经鞘瘤,也被称为神经鞘瘤,是良性的,生长缓慢,由周围神经鞘的施万细胞产生的包囊肿瘤。虽然极为罕见,它影响头部和颈部区域在大约25-45%的所有病例。口头,舌头是最常见的部位,很少累及前庭粘膜。这里,我们报道了一例罕见的13岁女孩的前庭粘膜神经鞘瘤病例,并对目前的文献进行了综述。临床上,根据年龄,site,和外观,良性肿瘤如脂肪瘤的诊断,纤维瘤,神经纤维瘤,并制作了唾液腺良性病变。切除活检仅显示AntoniA型组织,中央脱细胞嗜酸性Verocay体被纺锤形神经膜细胞包围,呈波浪状,以栅栏状排列的扭曲核。患者6个月后无复发。因此,这个案子很有趣,因为它的年龄很少,site,和组织病理学(AntoniA型神经鞘瘤)的初步诊断。这里,我们还对早期诊断病例的生长模式进行了假设.
Neurilemmoma, also known as Schwannoma, is a benign, slow-growing, encapsulated neoplasm that arises from Schwann cells of the peripheral nerve sheath. Although it is extremely rare, it affects the head and neck region in roughly 25-45% of all cases. Intraorally, the tongue is the most common site and is rarely involves vestibular mucosa. Here, we report a rare case of Schwannoma of vestibular mucosa in a 13-year-old girl and contribute a review to the current literature. Clinically, based on age, site, and appearance, a diagnosis of a benign tumour such as lipoma, fibroma, neurofibroma, and benign lesions of salivary glands was made. An excisional biopsy showed solely Antoni type A tissue with central acellular eosinophilic Verocay bodies surrounded by spindle-shaped neurilemma cells arranged compactly with wavy, twisted nuclei arranged in a palisaded manner. The patient was recurrence-free after 6 months. Hence, this case is of interest due to its rarity in terms of age, site, and histopathology (Antoni type A neurilemmoma) for a presumed initial diagnosis. Here, we also hypothesize regarding the type of growth pattern in the earlier diagnosed cases.