已对已发表的科学证据进行了非系统的审查,内容涉及在有效控制下进行手术腹腔内感染(IIA)的经验性抗生素治疗的持续时间。鉴于抗生素耐药性的逐渐增加,迫切需要制定策略来减轻微生物群的压力。Mazuski等人制定的美国指南。20171年,作为重点控制的腹腔内感染经验性抗生素治疗持续时间的建议的中心轴,并添加了包含Pubmed和GoogleScholar中关键字的所有文章的书目搜索。收集了21篇文章,这些文章涉及腹腔内感染中经验性抗生素治疗的持续时间,并控制了重点。有了美国的指导方针和这些文章,在24至72h之间没有危险因素的患者中,为经验性抗生素治疗的持续时间准备了建议。它应该是个性化的积极监测每24小时发烧,麻痹性肠梗阻和白细胞增多症(FIL),在早期发现并发症或需要改变抗生素治疗之前。短期治疗与持续时间较长的治疗一样有效,并且不良反应较少。因此,每日调整和重新评估经验性抗生素治疗的持续时间对于更好的实践至关重要.
A non-systematic review of the published scientific evidence has been carried out on the duration of empirical antibiotic treatment in surgical intra-abdominal infections (IIA) with effective focus control. Given the progressive increase in antibiotic resistance, it is urgent to have strategies to reduce the pressure on the microbiota. The American guidelines made by Mazuski et al. of 20171, as the central axis in the recommendations of the duration of empirical antibiotic treatment in intra-abdominal infections with control of the focus and a bibliographic search of all the articles that contained the keywords in Pubmed and Google Scholar is added. 21 articles referring to the duration of empirical antibiotic treatment in intra-abdominal infection with control of the focus are collected. With the American guidelines and these articles, a proposal is prepared for the duration of empirical antibiotic treatment in patients without risk factors between 24 and 72 h. And in those who present risk factors, it should be individualized with active monitoring every 24 h of fever, paralytic ileus and leukocytosis (FIL), before an early detection of complications or the need for changes in antibiotic treatment. Short treatments are just as effective as those of longer durations and are associated with fewer adverse effects, therefore, daily adjusting and reassessing the duration of empirical antibiotic treatment is essential for better practice.