■高收入和低收入国家的抗生素消费率都很高,但解决中低收入国家(LMICs)的抗生素使用问题对于对抗抗生素耐药性(AR)至关重要.
■这篇社论探讨了LMIC抗生素实践的现状,调查推动这种趋势的因素,包括缺乏资源公平和共同的全球责任,并探索(AR)的全球影响,特别强调迅速采取措施打击其传播。
■LMICs面临三个加剧AR的关键障碍:WASH服务不足,气候因素,滥用抗生素。缺乏卫生设施和清洁水会导致感染,而不良的卫生条件会加剧抗药性病原体的传播。全球战略应该不仅仅是简单地对LMICs进行抗生素滥用教育;他们还必须了解其影响,如长期的疾病和耐药细菌,如MRSA。应对这一挑战需要多方面的战略,包括改善WASH服务,承认气候影响,和收紧法规。确定讲卫生运动的优先顺序需要大量资金,社区参与,技术解决方案,与非政府组织的伙伴关系。利用社交媒体影响者可以提高AR意识。抗生素法规改革,制造质量,寻找抗生素替代品至关重要。抗菌药物管理计划和AI在管理耐药感染方面的潜力是值得注意的。
Antibiotic consumption rates are high in both high and low-income countries, but addressing antibiotic practices in low- and middle-income countries (LMICs) is crucial to combatting antibiotic resistance (AR).
This editorial examines the current landscape of antibiotic practices in LMICs, investigate the factors driving such trends including lack of resource equity and shared global responsibility, and explore (AR) global implications, with particular emphasis placed on swift measures to combat its spread.
LMICs face three key obstacles that exacerbate AR: inadequate WASH services, climate factors, and misuse of antibiotics. A lack of sanitation and clean water promotes infections, while poor hygiene exacerbates resistant pathogen spread. Global strategies should go beyond simply educating LMICs about antibiotic misuse; they must also understand its repercussions, such as prolonged illnesses and drug-resistant bacteria like MRSA. Addressing this challenge requires multifaceted strategies, including improving WASH services, acknowledging climate impacts, and tightening regulations. Prioritizing WASH requires significant funding, community participation, technology solutions, and partnerships with NGOs. Utilizing social media influencers can boost AR awareness. Antibiotic regulation reforms, manufacturing quality, and seeking antibiotic alternatives are vital. Antimicrobial Stewardship Programs and AI\'s potential in managing resistant infections are notable.