小型哺乳动物是非常受欢迎的伴侣动物,这些动物中特定肿瘤类型的发生率是广泛研究的主题。我们对103只宠物兔的生殖道和乳腺肿瘤以及肿瘤样病变的发生率进行了回顾性和比较分析,75只宠物老鼠,71只豚鼠,12只老鼠,11只仓鼠,八只非洲侏儒刺猬,四个雪貂和两个龙猫.结果表明,子宫肿瘤和肿瘤样病变在宠物兔中很常见,豚鼠和非洲侏儒刺猬。在宠物兔子中,最常见的子宫肿瘤是子宫内膜腺癌,而在豚鼠中,良性病变占主导地位(即,平滑肌瘤,子宫内膜腺瘤,囊性子宫内膜增生和蜕膜瘤)。非洲侏儒刺猬的子宫肿瘤包括腺肉瘤和子宫内膜息肉。仅在豚鼠中发现卵巢病变(卵巢腺瘤,网状囊肿)和非洲侏儒刺猬(主要是颗粒细胞肿瘤),而睾丸肿瘤被诊断为宠物兔,一只宠物老鼠和一只豚鼠.乳腺肿瘤在宠物兔中很常见,宠物老鼠,豚鼠,老鼠,仓鼠和非洲侏儒刺猬。在宠物老鼠中,最常见的乳腺肿瘤是纤维腺瘤,而在其他动物中,癌症占主导地位。在豚鼠身上,在较小程度上,在宠物老鼠中,相当比例的乳腺肿瘤发生在男性。豚鼠似乎易患导管起源的乳腺肿瘤。这项研究首次描述了宠物兔的子宫血管平滑肌瘤和Djungarian仓鼠和龙鼠的乳腺梭形细胞癌。
Small mammals are very popular companion animals, and the incidence of particular tumour types in these animals is the subject of extensive research. We carried out a retrospective and comparative analysis of the incidence of reproductive tract and mammary tumours and tumour-like lesions collected from 103 pet rabbits, 75 pet rats, 71 guinea pigs, 12 mice, 11 hamsters, eight African pygmy hedgehogs, four ferrets and two chinchillas. The results indicate that uterine tumours and tumour-like lesions are common in pet rabbits, guinea pigs and African pygmy hedgehogs. In pet rabbits, the most common uterine tumour was endometrial adenocarcinoma, while in guinea pigs benign lesions predominated (ie, leiomyoma, endometrial adenoma, cystic endometrial hyperplasia and deciduoma). Uterine tumours in African pygmy hedgehogs included adenosarcomas and endometrial polyps. Ovarian lesions were found only in guinea pigs (ovarian rete adenomas, rete cysts) and African pygmy hedgehogs (mostly granulosa cell tumours), while testicular tumours were diagnosed in pet rabbits, one pet rat and one guinea pig. Mammary tumours were common in pet rabbits, pet rats, guinea pigs, mice, hamsters and African pygmy hedgehogs. In pet rats, the most common mammary tumour was fibroadenoma, while in other animals carcinomas predominated. In guinea pigs and, to a lesser extent, in pet rats, a significant percentage of mammary tumours occurred in males. Guinea pigs seem to be predisposed to mammary tumours of ductal origin. This study describes for the first time uterine
angioleiomyoma in the pet rabbit and mammary spindle cell carcinoma in the Djungarian hamster and chinchilla.